Results 31 to 40 of about 235,191 (202)

Investigating the role of EPA and DHA on cellular oxidative stress; profiling antidiabetic and antihypertensive potential

Journal of Pharmacy and Bioallied Sciences, 2022
Background: Polyunsaturated fatty acids (PUFAs) remain part of the diet and are essential for growth and development. Furthermore, omega − 3 fatty acids boost various cardiovascular disease risk factors as well as lower blood pressure and cholesterol ...
Fahad K Aldhafiri
doaj   +1 more source

Oroxylum indicum (L.) Kurz extract inhibits adipogenesis and lipase activity in vitro

BMC Complementary and Alternative Medicine, 2018
Background Oroxylum indicum (L.) Kurz (O. indicum) is found in Thailand. It has been used for the treatment of obesity. This study aimed to investigate the effects of an O.
Tanaporn Hengpratom, Gordon M. Lowe, Kanjana Thumanu, Siriporn Suknasang, Kanokwan Tiamyom, Griangsak Eumkeb   +5 more
doaj   +1 more source

Cistanche tubulosa phenylethanoid glycosides suppressed adipogenesis in 3T3-L1 adipocytes and improved obesity and insulin resistance in high-fat diet induced obese mice

BMC Complementary Medicine and Therapies, 2022
Background Cistanche tubulosa is an editable and medicinal traditional Chinese herb and phenylethanoid glycosides are its major components, which have shown various beneficial effects such as anti-tumor, anti-oxidant and neuroprotective activities ...
Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv, Jinyao Li   +12 more
doaj   +1 more source

Characteristics of 3T3-L1 cells with overexpressed Brd2.

, 2013
3T3-L1 cells transfected with pmBrd2 and control (pcDNA3.1), respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have undergone differentiation ...
Jingyu Wang (292122), Min Yu (120607), Miaofang Dong (475610), Fangnian Wang (475613), Xiaoxia Liu (294088), Kun Zang (475609), Yuxiong Wang (152709), Yimin Li (475612), Ruixin Sun (475611), Yinong Huang (312166)   +9 more
core   +1 more source

Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation

Journal of Lipid Research, 2011
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that exerts insulinotropic and growth and survival effects on pancreatic β-cells.
Su-Jin Kim, Cuilan Nian, Christopher H.S. McIntosh   +2 more
doaj   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Differentiation of 3T3-L1 cells.

, 2016
Lipoprotein lipase (lpl) expression during the differentiation process of 3T3-L1 cells.
Allan Stensballe (293505), Steen B. Pedersen (331604), Toke P. Kroager (3149895), Bjørn Richelsen (844955), Kristian W. Sanggaard (110149), Jan J. Enghild (110183), Anders D. Knudsen (3149898), Mark K. Nøhr (844950), Jens Ølholm (3149892)   +8 more
core   +1 more source

Phosphatidylcholine induces apoptosis of 3T3-L1 adipocytes [PDF]

, 2011
Background Phosphatidylcholine (PPC) formulation is used for lipolytic injection, even though its mechanism of action is not well understood. Methods The viability of 3T3-L1 pre-adipocytes and differentiated 3T3-L1 cells was measured after treatment of ...
Hailan Li, Ji Hoon Jeong, Jong-Hyuk Lee, Kwang Jin Baek, Yoosik Yoon, Kwon Nyoun Soo, Dong-Seok Kim, Yun Hye-Young, Kim Dong-Seok, Nyoun Soo Kwon, Jeong Ji Hoon, Baek Kwang Jin, Su Yeon Kim, Li Hailan, Kim Su Yeon, Yoon Yoosik, Hye-Young Yun, Lee Jong-Hyuk   +17 more
core   +1 more source

Antidiabetic effect of combination of fractionated-extracts of Andrographis paniculata and Centella asiatica: In vitro study

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To examine the effect of combination of Andrographis paniculata herb fraction (AHF) and Centella asiatica herb fraction (CHF) on PPARγ and GLUT4 mRNA expressions in 3T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods:
LOM. Fitrawan, R Ariastuti, R R Tjandrawinata, A E Nugroho, S Pramono   +4 more
doaj   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source