Results 101 to 110 of about 21,834 (203)

Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels

Frontiers in Molecular Neuroscience, 2017
The development of neuroprotective and repair strategies for treating progressive multiple sclerosis (MS) requires new insights into axonal injury. 4-aminopyridine (4-AP), a blocker of voltage-gated K+ (Kv) channels, is used in symptomatic treatment of ...
Peter Jukkola, Yuanzheng Gu, Amy E. Lovett-Racke, Chen Gu, Chen Gu   +4 more
doaj   +1 more source

Exploring the use of dalfampridine (4‐aminopyridine) for treatment of ataxia in cerebellar stroke

PM&R, EarlyView.
Arjun Kotwal, Prashant Yadav, Veyola Rezkalla, Alison Mautner, Gilbert Siu   +4 more
wiley   +1 more source

The toxic sheep collar for control of sheep-killing coyotes: A progress report [PDF]

, 1978
The toxic sheep collar is the most selective method known for killing coyotes that prey on domestic sheep. The concept dates back to the early 1900's and has been studied at the Denver Wildlife Research Center (DWRC) since 1974.
Connolly, Guy E., Griffiths, Richard E., Jr., Savarie, Peter J.   +2 more
core  

Synthesis, Characterization and Antibacterial Properties of Complex [Ag(SCN)(2-NH2py)] [PDF]

E3S Web of Conferences
The reaction of AgSCN with 2-aminopyridine in ammonia solution produces the colorless crystal of catena-poly [Ag(SCN))(C6H5N2)]n. The crystals were characterized by FTIR analysis and single crystal X-Ray diffraction.
Mariyam Dewi, Dasna I. Wayan, Wijaya Husni Wahyu, Danar   +3 more
doaj   +1 more source

Modeling seizure networks in neuron-glia cultures using microelectrode arrays

Frontiers in Network Physiology
Epilepsy is a common neurological disorder, affecting over 65 million people worldwide. Unfortunately, despite resective surgery, over 30% of patients with drug-resistant epilepsy continue to experience seizures.
Ujwal Boddeti, Ujwal Boddeti, Jenna Langbein, Darrian McAfee, Marcelle Altshuler, Muzna Bachani, Hitten P. Zaveri, Dennis Spencer, Kareem A. Zaghloul, Alexander Ksendzovsky   +9 more
doaj   +1 more source

Eficacia de la 4-aminopiridina en el tratamiento de pacientes diagnosticados de ataxia con downbeat nystagmus de causa idiopática [PDF]

, 2012
L'atàxia amb downbeat nystamgus (ADBN) es una síndrome clínica que cursa amb atàxia vestíbulo-cerebel·losa i downbeat nystagmus. Es va valorar la seguretat i eficàcia del bloquejador de canal de potassi 4-aminopiridina (4-AP) pel tractament d'aquesta ...
Latorre Murillo, Pilar, Martínez Fernández, Raül, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
core  

GABA_B receptor outward currents are transiently disclosed by the convulsant 4-aminopyridine in vitro. [PDF]

Curr Res Neurobiol, 2023
Cattani A, Wang S, Lévesque M, Farmer JP, Dudley RWR, Avoli M.   +5 more
europepmc   +1 more source

Osborn Waves: History and Significance [PDF]

, 2004
The Osborn wave is a deflection with a dome or hump configuration occurring at the R-ST junction (J point) on the ECG (Fig. 1). In the historical view, different names have been used for this wave in the medical literature, such as “camel-hump sign ...
Maruyama, Mitsunori, Kobayashi, Yoshinori, Kodani, Eitaroh, Hirayama, Yoshiyuki, Atarashi, Hirotsugu, Katoh, Takao, Takano, Teruo   +6 more
core   +1 more source

In vivo laser speckle contrast imaging of 4-aminopyridine- or pentylenetetrazole-induced seizures. [PDF]

APL Bioeng, 2023
Wang Y, Tsytsarev V, Liao LD.
europepmc   +1 more source

Dual separable feedback systems govern firing rate homeostasis. [PDF]

, 2019
Firing rate homeostasis (FRH) stabilizes neural activity. A pervasive and intuitive theory argues that a single variable, calcium, is detected and stabilized through regulatory feedback.
Davis, Graeme W, Jones, Ryan, Kulik, Yelena, Moughamian, Armen J, Whippen, Jenna   +4 more
core