Results 101 to 110 of about 24,212 (246)

Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors [PDF]

, 2001
Airway neuroepithelial bodies sense changes in inspired O2, whereas arterial O2 levels are monitored primarily by the carotid body. Both respond to hypoxia by initiating corrective cardiorespiratory reflexes, thereby optimising gas exchange in the face ...
Kemp, P.J., Peers, C.
core   +4 more sources

Proceedings of Abstracts Engineering and Computer Science Research Conference 2019 [PDF]

, 2019
© 2019 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Adams, Roderick, Amafabia, Daerefa-a, Barker, Trevor, Beka, Nathan, Bhavsar, Ronakben, Bonivart, Agnes, Canoville, Paul, Cañamero, Lola, CHEN, Yong Kang, CHEN, Yong Kang, Chrysanthou, Andreas, Counsell, Nathan, Crook, Brian, Davey, Neil, David-West, Opukuro, Denai, Mouloud, Dhakal, Hom, Drix, Damien, Goncharenko, Julia, Grasso, Marzio, Hafner, Verena Vanessa, Hall, Samantha, Haritos, George, Hassan, Eheda, Helian, Na, Herfatmanesh, Mohammad Reza, Ismail, Sikiru O., Johnston, Ian, Johnston, Ian, Kadir, Shabnam, Kaye, Richard, Khan, Imran, Kirner, Raimund, Kirner, Raimund, Klaholz, Ingo, Klusak, Jan, Kourtessis, Pandelis, Lane, Peter, Lekkala, Himayasri Rao, Lilley, Mariana, Mayor, David, McCluskey, Daniel, McCluskey, Daniel, Menon, Catherine, Metzner, Christoph, Miko, Rebecca, Montalvão, Diogo, Mporas, Iosif, Munro, Ian, Nehaniv, Chrystopher, Newman, James, Nwawe, Richard, Panday, Deepak, Partou, Helen, Pissanidis, Georgios, Polani, Daniel, Ren, Guogang, Robinson, Matthew, Rosiello, Vincenzo, Sayers, Paul, Schilstra, Maria, Schirmer, Pascal, Schmuker, Michael, Siadati, Rana, Sinha, Ankur, Skaltsas, Grigorios, Steffert, Tony, Steuber, Volker, Steuber, Volker, Suckow, Bjorn, Sun, Yi, Sun, Yichuang, Sunmola, Funlade, Sutton, Samuel, te Boekhorst, Rene, Toffe, Gilles, Tracey, Mark, Tveretina, Olga, Veneziano, Vito, Verma, Alok, Wang, Yuan, Wernick, Paul   +81 more
core   +2 more sources

Developmental features of 4-aminopyridine induced epileptogenesis

Developmental Brain Research, 1996
4-Aminopyridine (4-AP, 50 microM), perfused in rat hippocampal slices from postnatal days 2-30 (P2-P30), induced in the CA3 area the appearance of spontaneous epileptiform discharges, short (interictal-like) and sustained (ictal-like), as well as slow potential.
Psarropoulou, C., Avoli, M.
openaire   +3 more sources

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan, Anupam Hazra, Ashan Jayasekera, Katherine Huang, Shuna Whyte, Leolie Telford‐Cooke, Kamilah Lakhani, Xiaomeng Li, Rebecca Shields, Angeline Kosim, Darwin Su, Carol Murray, Mark O. Cunningham   +12 more
wiley   +1 more source

On the dilemma of fractal or fractional kinetics in drug release studies: A comparison between Weibull and Mittag-Leffler functions

, 2018
We compare two of the most successful models for the description and analysis of drug release data. The fractal kinetics approach leading to release profiles described by a Weibull function and the fractional kinetics approach leading to release profiles
Kosmidis, Kosmas, Macheras, Panos
core   +1 more source

Exploring the use of dalfampridine (4‐aminopyridine) for treatment of ataxia in cerebellar stroke

PM&R, EarlyView.
Arjun Kotwal, Prashant Yadav, Veyola Rezkalla, Alison Mautner, Gilbert Siu   +4 more
wiley   +1 more source

Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels

Frontiers in Molecular Neuroscience, 2017
The development of neuroprotective and repair strategies for treating progressive multiple sclerosis (MS) requires new insights into axonal injury. 4-aminopyridine (4-AP), a blocker of voltage-gated K+ (Kv) channels, is used in symptomatic treatment of ...
Peter Jukkola, Yuanzheng Gu, Amy E. Lovett-Racke, Chen Gu, Chen Gu   +4 more
doaj   +1 more source

Modulating Electronic Properties of N‐Heterocyclic Carbene Ligands: Effects on the Pd‐Catalyzed Buchwald–Hartwig Amination

European Journal of Inorganic Chemistry, Volume 29, Issue 2, January 12, 2026.
Pd complexes with electronically modified NHCs (NHC = N‐heterocyclic carbene) were analyzed in the Buchwald–Hartwig Amination under both strongly and weakly basic conditions. Investigations into the steric and electronic properties of the ligands are detailed.
Meilin Q. Lim, Cassandra DeFrancesco, Kasandra J. Brick, Sterling Renzoni, Eric Fortin Constant, Alexander A. Glover, Casey A. Lenart, Jesse LeBlanc, Charley Garrard, Eric C. Keske   +9 more
wiley   +1 more source

Modifications to synaptic transmission at group Ia synapses on cat spinal motoneurones by 4‐aminopyridine. [PDF]

, 1981
Julian Jack, Stephen Redman, Ken C. L. Wong   +2 more
openalex   +1 more source

Generalization of seizures parallels the formation of "dark" neurons in the hippocampus and pontine reticular formation after focal-cortical application of 4-aminopyridine (4-AP) in the rat. [PDF]

, 2008
Distribution and time course of the occurrence of "dark" neurons were compared with the EEG activity and behavior of rats during 4-aminopyridine (4-AP) induced epileptic seizures. A crystal of the K(+) channel blocker 4-AP (0.5 mg/kg) was placed onto the
Baracskay, P, Czurkó, A., Juhász, G, ORBAN, Gergely, Szepesi, Z   +4 more
core   +1 more source