Results 71 to 80 of about 3,474 (171)

Serum metabolite profiling of a 4-Nitroquinoline-1-oxide-induced experimental oral carcinogenesis model using gas chromatography-mass spectrometry. [PDF]

PeerJ, 2021
Ge S, Zhou H, Zhou Z, Liu L, Lou J.
europepmc   +1 more source

Inhibition of TLR4 enhances oxaliplatin chemotherapy sensitivity in esophageal squamous cell carcinoma by suppressing inflammation and glycolysis

BMC Gastroenterology
Background Oxaliplatin (OXA) has become a key chemotherapeutic agent in the treatment of esophageal squamous cell carcinoma (ESCC). Toll-like receptor 4 (TLR4) is frequently upregulated in OXA-treated tumors, yet its role in regulating OXA sensitivity in
Ziqi Zhu, Meng Zhang, Zequn Di, Xin Tao, Yaohui Dai, Zhiqiang Zhan, Hongping Chen   +6 more
doaj   +1 more source

Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

Molecular Systems Biology, 2018
Condition‐dependent genetic interactions can reveal functional relationships between genes that are not evident under standard culture conditions. State‐of‐the‐art yeast genetic interaction mapping, which relies on robotic manipulation of arrays of ...
J Javier Díaz‐Mejía, Albi Celaj, Joseph C Mellor, Atina Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile, Marta Verby, Anna Karkhanina, YiFan Zhang, Cassandra Wong, Justin Rich, D'Arcy Prendergast, Gaurav Gupta, Sedide Öztürk, Daniel Durocher, Grant W Brown, Frederick P Roth   +20 more
doaj   +1 more source

Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells

Genetics and Molecular Biology, 2009
Spearmint leaves (Mentha spicata L.) contain high levels of antioxidants that are known to protect against both exogenous and endogenous DNA damage. In this study, the protective effects of the hexane fraction (HF), chloroform fraction (CF) and ethyl ...
Ponnan Arumugam, Arabandi Ramesh
doaj  

RTN4IP1 Contributes to ESCC via Regulation of Amino Acid Transporters

Advanced Science
Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of esophageal cancer cases. The lack of effective therapeutic targets makes it difficult to improve the overall survival of patients with ESCC.
Huifang Wei, Dengyun Zhao, Yafei Zhi, Qiong Wu, Jing Ma, Jialuo Xu, Tingting Liu, Jing Zhang, Penglei Wang, Yamei Hu, Xinyu He, Fangqin Guo, Ming Jiang, Dandan Zhang, Wenna Nie, Ran Yang, Tongjin Zhao, Zigang Dong, Kangdong Liu   +18 more
doaj   +1 more source

4-Nitroquinoline-1-Oxide [PDF]

, 2020
openaire   +1 more source

Integration of network toxicology and transcriptomics reveals the potential regulatory role of the 'Arecoline/4-NQO-AKT1-m6A factor' axis in the development of OSCC

Frontiers in Oncology
ObjectiveThe synergistic carcinogenic effect of areca nut chewing and tobacco exposure is a major risk factor for oral squamous cell carcinoma (OSCC).
Yongle Qiu, Yamei Wang, Jiahong Zhao, Yi Cheng, Yang Liu, Hui Xu, Zhizheng Zhuang, Feifei Lv   +7 more
doaj   +1 more source

Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia

Neoplasia: An International Journal for Oncology Research
Oral squamous cell carcinoma (OSCC) is characterized by aggressiveness and a poor prognosis, in part because most patients are diagnosed during the later stages of the disease. B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), part
Jorge Baquero, Xiao-Han Tang, Daniel Galke, Theresa Scognamiglio, Tuo Zhang, Dawson Miller, Qiuying Chen, Steven Gross, Lorraine J. Gudas   +8 more
doaj   +1 more source

The efficiency of propranolol on occurrence and development of 4-nitroquinoline 1-oxide-induced squamous cell carcinoma of the tongue in rats. [PDF]

J Oral Maxillofac Pathol, 2020
Cubuk S, Uckan S, Ozdemir H, Taslica ZF, Bacanli D.   +4 more
europepmc   +1 more source

Free Radical Reaction of 4-Nitroquinoline 1-Oxide

YAKUGAKU ZASSHI, 1965
T, KOSUGE, K, ADACHI, M, YOKOTA, T, NAKAO   +3 more
openaire   +3 more sources