Results 81 to 90 of about 3,474 (171)

TLR4 promotes ESCC progression by driving inflammation and metabolic reprogramming through SLC39A10-mediated zinc homeostasis

Journal of Translational Medicine
Background Toll-like receptor 4 (TLR4), a key pattern recognition receptor in innate immunity, is frequently overexpressed in various malignancies including esophageal squamous cell carcinoma (ESCC). While TLR4’s oncogenic potential has been established,
Ziqi Zhu, Mingyang Zhang, Meng Zhang, Xin Tao, Jiang Gu, Hongping Chen, Bentong Yu   +6 more
doaj   +1 more source

Metabolism of 4-nitroquinoline 1-oxide. IV. Quantitative determination of in vivo conversion of 4-nitroquinoline 1-oxide in subcutaneous tissue of rat.

Gan, 1968
MATSUSHIMA, Taijiro, KOBUNA, Ikuko, FUKUOKA, Fumiko, SUGIMURA, Takashi   +3 more
openaire   +2 more sources

Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer. [PDF]

Oncol Rep, 2018
Wu JS, Li L, Wang SS, Pang X, Wu JB, Sheng SR, Tang YJ, Tang YL, Zheng M, Liang XH.   +9 more
europepmc   +1 more source

Carcinogenicity of 4-nitroquinoline 1-oxide analogs: pyridine series.

Gan, 1971
ARAKI, Misako, KOGA, Chieko, KAWAZOE, Yutaka   +2 more
openaire   +2 more sources

Sex-Related Differences in Histone Acetylation and Tumor Development in a 4-Nitroquinoline 1-Oxide and Ethanol-Induced Oral Squamous Cell Carcinoma Mouse Model. [PDF]

J Oral Pathol Med
Nazário WR, Costa ARGF, de Oliveira Santos D, Del Nero NRD, Rodrigues TS, Borges LDF, Ueira-Vieira C, Cardoso SV, Loyola AM, de Faria PR.   +9 more
europepmc   +1 more source

4-Nitroquinoline 1-Oxide-Induced Tongue and Esophagus Carcinogenesis in Obese and Diabetic TSOD Mice. [PDF]

World J Oncol, 2017
Tanaka T, Kawabata K, Sugie S.
europepmc   +1 more source

The metabolism of 4-nitroquinoline 1-oxide. I. Conversion of 4-nitroquinoline 1-oxide to 4-aminoquinoline 1-oxide by rat liver enzymes.

Gan, 1965
SUGIMURA, Takashi, OKABE, Kazuko, ENDO, Hideya   +2 more
openaire   +2 more sources

Adverse Outcome Pathway-Informed Integrated Testing to Identify Chemicals Causing Genotoxicity Through Oxidative DNA Damage: Case Study on 4-Nitroquinoline 1-Oxide. [PDF]

Environ Mol Mutagen
Huliganga E, Cho E, Swartz CD, Williams A, Recio L, Salk JJ, Marchetti F, Yauk CL.   +7 more
europepmc   +1 more source

4-nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis. [PDF]

Melanoma Res, 2016
Wang LE, Li C, Xiong P, Gershenwald JE, Prieto VG, Duvic M, Lee JE, Grimm EA, Hsu TC, Wei Q.   +9 more
europepmc   +1 more source

Action of 4-nitroquinoline 1-oxide on mitochondrial DNA in yeast.

Gan, 1974
MORITA, Tamotsu, MIFUCHI, Ichiji
openaire   +2 more sources