Results 101 to 110 of about 11,638,573 (298)

Designing of Promising VEGFR‐2 Inhibitors by Using QSAR Modeling, Molecular Docking, and Molecular Dynamic Simulation: Implications Toward the Treatment of Cancer

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Background The vascular endothelial growth factor receptor 2 (VEGFR‐2) is considered one of the most studied therapeutic targets for the treatment of various cancers. Among many heterocyclic compounds, the oxadiazole derivatives have been reported to exhibit significant anticancer activities. Therefore, exploring these derivatives against VEGFR‐2 could
Aisha A. Alsfouk, Pervaiz Ali Channar, Muhammad Sajjad Bilal, Syeda Abida Ejaz, Song J. A. Kim, Sohini Basu Roy   +5 more
wiley   +1 more source

Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties. [PDF]

, 2007
A series of new benzenesulfonamides, most of which are chiral, incorporating 1, 3, 4-oxadiazole and amino acid moieties have been synthesized. Some of these compounds were screened for antimalarial activity and also evaluated for their ability to inhibit
Claudiu T. Supuran, Javid H. Zaidi, Juan Rodrigues, Muhammad Arfan, Muhammad Zareef, Neira Gamboa de Domínguez, Rashid Iqbal   +6 more
core   +2 more sources

Synthetic Strategies to Access Fluorinated Azoles

European Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber, Mario Djugovski, Tzu‐Yu Huang, Sweta Adhikari, Sudeshna Roy   +4 more
wiley   +1 more source

Sy nthesis of Some New Schifrs-Bases Derived From 2-(4-m ethoxy phenyl)-5- (4-amino phenyl)-1,3,4-0xadiazole

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
A new compound  2-(4-methoxyphcnyl)-5-(4-aminophenyl)-1,3,4- oxadiazole (VI) was prepared by intramol ecular condensation reaction followed  by elimination  of some simple  moieties such  as IhO  and HCI by using  POCI3 with acid hydrazide.
J. H Tomma
doaj  

3,3′-(Diazene-1,2-diyl)bis[4-(nitroamino)-1,2,5-oxadiazole 2-oxide]

Molbank, 2018
The nitramino derivatives of furoxans are of specific interest as precursors for the preparation of high energy salts with nitrogen-rich cations. In this communication, the 3,3′-(diazene-1,2-diyl)bis[4-(nitroamino)-1,2,5-oxadiazole 2-oxide] was prepared ...
Alexander Larin, Igor Ovchinnikov, Leonid Fershtat, Nina Makhova   +3 more
doaj   +1 more source

Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives

Molecules, 2009
New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate ...
Abdul Jabar Kh. Atia
doaj   +1 more source

Studies on Potential Pesticides Part-XII [PDF]

, 2014
Fifteen N/sup 1/-(4-Nitrophenoxyacetyl)N/sup 4/-aryl/cryclohexyl-3-thiosemicarbazide, eleven 3-(4-Nitrophenoxymethyl)-4-aryl/cyclohexyl-5-mercapto1,2,4-triazoles and four 2-Arylamino-5-(4-Nitrophenoxymethyl)-1,3,4-oxadiazole derivatives were prepared and
Misra, Hemant K., Sen, Anil K.
core   +2 more sources

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

Pharmaceuticals
Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies.
Tatiana V. Zinevich, Ivan O. Maslov, Olga G. Kirichenko, Sergey V. Shorshnev, Maxim A. Gureev, Fedor M. Dolgushin, Yuri B. Porozov, Vladimir M. Trukhan   +7 more
doaj   +1 more source

Polymers Containing 1, 3, 4-Oxadiazole Rings for Advanced Materials

Memoirs of the Scientific Sections of the Romanian Academy, 2011
This paper presents the synthesis, properties and potential applications of new polymers containing 1, 3, 4-oxadiazole rings, tacking into account the requirements of the modern technologies. Two classes of polymers containing oxadiazole rings were approached: polyamides and polyimides.
Mariana-Dana Damaceanu, Radu-Dan Rusu, Maria Bruma   +2 more
openaire   +1 more source

Synthesis and anti-tubercular evaluation of some novel (E)-5-(4-(benzylidene amino) phenyl)-1,3,4-oxadiazole-2-thiol derivatives

, 2023
Kuntal Das, Paramita Das, Raha Orfali, A. R. Ramya, Alex Joseph, Mohd Imran, Syed Mohammed Basheeruddin Asdaq, Sultan Alshehri, Ali A. Rabaan, Mohammed Aljeldah, Bashayer M. AlShehail, Mohammed Alissa, Nawal Al Kaabi, Ameen S. S. Alwashmi, Mashael Alhajri, Mustafa A. Najim, Farhana Yasmin   +16 more
openalex   +1 more source