INSILICO DESIGN, SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL BENZOTHIAZOLE DERIVATIVES AS ANTI-CANCER AGENTS [PDF]
, 2017 Objectives: Cancer is a disease characterized by uncontrollable, irreversible, independent, autonomous, uncoordinated and relatively unlimited and abnormal over growth of tissues.
Chandran, Deepthy +2 more
core +1 more source
EX VIVO ANTICOAGULANT ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES [PDF]
, 2015 Objective: The present medication for the management of arterial thromboembolism (ATE) disorders by anticoagulant therapy highlights its lacunae due to recurrent ATE episodes and indicates the need for better anticoagulant agents with clinical advantage ...
Gurupadayya, B. M., Vishwanathan, B.
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Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies. [PDF]
Pharmaceuticals (Basel), 2020 Alam MM +5 more
europepmc +1 more source
SYNTHESIS OF QUINOLINYL-OXADIAZOLE AS A POTENT ANTIBACTERIAL AGENT AND SA-FABI INHIBITOR [PDF]
, 2015 Objective: Microbial resistance to currently marketed drugs is a serious problem worldwide and there is a vital need to develop novel antibiotics. Enoyl-ACP reductase (FabI) is essential for fatty acid biosynthesis and hence serves as an appealing target
D’almeida, Laveeta +3 more
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New charge-transport materials for OLED applications [PDF]
, 2006 Novel fluorene-1 ,3,4-oxadiazole and spirobifluorene-1 ,3,4-oxadiazole compounds 202 and 211, respectively, have been synthesised. Compound 202 was blended with MEHPPV in various ratios and incorporated into organic light-emitting diodes (OLEDs).The ...
Kamtekar, Kiran
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Sensitization of an oxadiazole derivative as an organic photoconductor [PDF]
, 1982 The sensitization and the spectral sensitization of the photoconductivity of an organic derivative, 2,5-bis (p-diethyl-aminophenyl) - 1,3, 4-oxadiazole, was studied once an electrostatic sensitometer had been built.
Ceintrey, Claude G.
core +1 more source
Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo. [PDF]
Int J Mol Sci, 2020 Markov AV +8 more
europepmc +1 more source
Synthesis, Characterization & Biological Evaluation of Some Novel 1, 3, 4-Oxadiazole Derivatives [PDF]
, 2019 Substituted oxadiazole, 5-(2-hydroxyphenyl)-1, 3, 4-oxadiazole-2(3H)-thione was synthesized from salicylic acid. The titled oxadiazole derivatives were synthesized by making substitution at free N-(3H) position of 5-(2-hydroxyphenyl)-1, 3, 4 ...
Abirami, A V
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Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties [PDF]
DNA gyrase and topoisomerase IV show great potential as targets for antibacterial medicines. In recent decades, various categories of small molecule inhibitors have been identified; however, none have been effective in the market. For the
Abou-Zied, Hesham A. +7 more
core +2 more sources
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2019 Condensation of 4-methoxybenzoyl hydrazine with 4- aminobenzoic acid in the presence of POCl3 gave the oxadiazole derivative [III] .This compound was demethylated with aluminium chloride to give series of 2- (4-hydroxy phenyl)-5-(4-amino phenyl) 1,3 ...
J. H. Tomma, A. H. Raheema, I. H. Rouil
doaj