Results 241 to 250 of about 11,638,573 (298)

Design, Synthesis, and Pesticidal Activities of Pyrimidin-4-amine Derivatives Bearing a 5-(Trifluoromethyl)-1,2,4-oxadiazole Moiety.

Journal of Agricultural and Food Chemistry, 2021
It is important to discover new pesticides with new modes of action because of the increasing evolution of pesticide resistance. In this study, a series of novel pyrimidin-4-amine derivatives containing a 5-(trifluoromethyl)-1,2,4-oxadiazole moiety were ...
Xing-Hai Liu, Yong Wen, Long Cheng, Tianming Xu, Ning‐Jie Wu   +4 more
semanticscholar   +1 more source

Antibacterial and Antiviral Activities of 1,3,4-Oxadiazole Thioether 4H-Chromen-4-one Derivatives.

Journal of Agricultural and Food Chemistry, 2021
Various 1,3,4-oxadiazole thioether 4H-chromen-4-one derivatives were conceived. The title compounds demonstrated striking inhibitory effects against Xac, Psa, and Xoo. EC50 data exhibited that A8 (19.7 μg/mL) had better antibacterial activity against Xoo
Feng Peng, Tin-yin Liu, Qifan Wang, Fang Liu, Xiao Cao, Jinsong Yang, Li-wei Liu, C. Xie, Wei Xue   +8 more
semanticscholar   +1 more source

Synthetic Transformation of 4-fluorobenzoic acid to 4-fluorobenzohydrazide Schiff Bases and 1,3,4-Oxadiazole Analogs having DPPH Radical Scavenging Potential

Letters in Drug Design & Discovery, 2022
Synthesis of 4-fluorobenzohydrazide Schiff bases and 1,3,4-oxadiazole analogs has DPPH radical scavenging potential. Synthetic antioxidants are widely used because they are effective and cheaper than natural antioxidants.
Momin Khan, Zala Fazal, Aftab Alam, M. Ibrahim, Tehseen Ali, Mahboob Ali, Hafiz Danyal Khan   +6 more
semanticscholar   +1 more source

An Overview: 1, 3, 4- oxadiazole and its uses

Asian Journal of Research in Chemistry, 2021
Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen.
Anuja S. Patil., Shrinivas K. Mohite
openaire   +1 more source

New quinoxalin‐1,3,4‐oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

Archiv der Pharmazie, 2021
A new series of quinoxalin‐1,3,4‐oxadiazole (10a–l) derivatives was synthesized and evaluated against some metabolic enzymes including human carbonic anhydrase (hCA) isoenzymes I and II (carbonic anhydrases I and II), cholinesterase (acetylcholinesterase
R. Mirzazadeh, M. Asgari, Ebrahim Barzegari, Keyvan Pedrood, M. Mohammadi‐Khanaposhtani, Maedeh Sherafati, B. Larijani, H. Rastegar, H. Rahmani, M. Mahdavi, Parham Taslimi, E. Üç, I. Gulcin   +12 more
semanticscholar   +1 more source

Design, Synthesis and Bio‐Evaluation of Novel Chalcones Bridged with 1,3,4‐Oxadiazole Linkers: ADMET and Docking Analysis

Chemistry and Biodiversity, 2022
In this article, we prepared a novel series of 1,3,4‐oxadiazoles containing chalcone analogs via replacement of phthalazine which had increased antibacterial activity and the final compounds were confirmed by proton, carbon nuclear magnetic resonance ...
G. Gogisetti, U. Kanna, Vishal Sharma, Tejeswara Rao Allaka, Bhaskara Rao Tadiboina   +4 more
semanticscholar   +1 more source

[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Mini-Reviews in Medicinal Chemistry, 2014
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc.
Rajesh O, Bora, Bashir, Dar, Vidya, Pradhan, Mazahar, Farooqui   +3 more
openaire   +2 more sources

Quinazoline clubbed thiazole and 1,3,4-oxadiazole heterocycles: synthesis, characterization, antibacterial evaluation, and molecular docking studies

, 2021
In search of potent antibacterial agents, a series of novel quinazolines, bearing thiazole and 1,3,4-oxadiazole heterocycles 6a–j (3-(4-methyl-5-(4-((arylamino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)thiazol-2-yl)-2-phenylquinazolin-4(3H)-ones)
N. Desai, N. Shihory, A. Khasiya, Unnati Pandit, V. Khedkar   +4 more
semanticscholar   +1 more source

2, 5-Dialkyl-1, 3, 4-oxadiazoles

Chemistry of Heterocyclic Compounds, 1970
A single stage method has been developed for the preparation of 2, 5-dialky-1, 3, 4-oxadiazoles from aliphatic carboxylic acids, by boiling with hydrazine hydrochloride in phosphoryl chloride. A mechanism for the synthesis is suggested. The oxadiazoles are characterized, and the group refractivity of the 1, 3, 4-oxadiazole ring has been determined.
M. S. Skorobogatova, Ya. A. Levin, O. A. Raevskii   +2 more
openaire   +1 more source

Synthesis of 1, 3, 4-Oxadiazole

Asian Journal of Research in Chemistry, 2017
Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized ...
Maqdoom Farooqui, Syed Nazimuddin
openaire   +1 more source