Results 91 to 100 of about 61,740 (193)
Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes [PDF]
, 2013 Bacteria deploy a range of chemistries to regulate their behaviour and respond to their environment. Quorum sensing is one mean by which bacteria use chemical reactions to modulate pre-infection behaviour such as surface attachment.
A Camilli +60 more
core +3 more sources
Addiction, EarlyView.Abstract Background and aims Tobacco‐cannabis co‐use is associated with increased psychosocial and health harms; however, the treatment literature assessing the impact of co‐use has been mixed and suffers from critical limitations. To date, no prospective studies have evaluated the degree to which cannabis co‐use affects tobacco cessation, nor are ...
Erin A. McClure +6 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth +5 more
wiley +1 more source
Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram +5 more
wiley +1 more source
Insights into Cross-Kingdom Plant Pathogenic Bacteria [PDF]
, 2011 Plant and human pathogens have evolved disease factors to successfully exploit their respective hosts. Phytopathogens utilize specific determinants that help to breach reinforced cell walls and manipulate plant physiology to facilitate the disease ...
Alfano +106 more
core +2 more sources
The FEBS Journal, EarlyView.Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Инфекция и иммунитет, 2019 Background: Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial infections and one of the leading causes of many diseases, and become public health concern especially when characterized as multidrug resistance ...
Samer A. MH Al-Hilali +2 more
doaj
"One Pot" Synthesis of 1,5-Diaza-2,3,6,7-Thetrahydro-4-Methyl-Phenanthrene-4,8-Dione From Corresponding Bis-Beta-Amino Acid [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1999 The cyclization of b-anilino propionic acids in the presence of polyphosphoric acid (PPA) afforded the 2,3-Dihydroquinoline-4-(1H)-ones in good yields. N,N'-bis(2-carboxyethyl)-4-methyl-1,2-diaminobenzene (7) is cyclized under this condition to produce ...
Abbas Shokravi +1 more
doaj
Recent advances in the synthesis of pharmaceutically active 4-quinolone and its analogues: a review. [PDF]
RSC Adv, 2023 Dine I, Mulugeta E, Melaku Y, Belete M.
europepmc +1 more source
Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria [PDF]
, 2017 The susceptibility of 11 clinical isolates of Mycobacterium tuberculosis, 3 M. kansasii,3 M. xenopi, 2 M.scrofulaceum, 2 M. marinum, 2 M. malmoense to fleroxacin,ciprofloxacin, norfloxacin, rifampicin, isoniazid, ethambutol, and streptomycin was ...
Hohl, Peter +2 more
core