Results 71 to 80 of about 61,740 (193)

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis [PDF]

, 2015
Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for pulmonary exacerbations,
Alan J. Knox, Alan R. Smyth, Andrew Clayton, Andrew W. Fogarty, David A. Barrett, David Honeybourne, Douglas L. Forrester, Edward F. Nash, Helen L. Barr, Jaffar-Bandjee, Jane Dewar, Joanna L. Whitehouse, Miguel Cámara, Nigel Halliday, Paul Williams, Rebecca Simms   +15 more
core   +2 more sources

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

Laboratory Survey of Fluoroquinolone Activity [PDF]

, 2017
Fluoroquinolones are active against a wide variety of bacteria. The antibacterial spectra of fluoroquinolones encompass staphylococci, Bacillus species, and Corynebacterium species implicated in infections of the immunocompromised host ...
Bellido, Francis, Pechère, Jean-Claude
core  

Quinolone tolerance in Escherichia coli due to defects in the adenosine ribonucleotides de novo biosynthesis pathway

mLife, EarlyView.
Abstract Central carbon metabolism is thought to link reactive oxygen species (ROS) with antibiotic‐mediated bacterial death. During enrichment screening of Escherichia coli with the first‐generation quinolone oxolinic acid, unstable antibiotic‐tolerant mutants containing deficiencies in purB were obtained.
Weiwei Zhu, Yuejuan Nong, Jie Su, Jingwen Yang, Lina Ma, Yunxin Xue, Dai Wang, Jianjun Niu, Karl Drlica, Xilin Zhao   +9 more
wiley   +1 more source

Fleroxacin (Ro 23-6240): activity in virtro against 355 enteropathogenic and non-fermentative Gram-negative bacilli and Legionella pneumophila [PDF]

, 2017
The antibacterial activity of fleroxacin (Ro 23-6240, AM-833), a new 6-fluoroquinolone, was determined against 149 strains of enteropathogenic bacteria (17 species) and 191 strains (28 species) of glucose non-fermentative Gram-negative rods (excluding ...
Graevenitz, A. von, Hohi, P., Zollinger-Iten, J.   +2 more
core  

Proliferation of antibiotic resistance genes in coastal recirculating mariculture system [PDF]

, 2019
The abuse of antibiotics has caused the propagation of antibiotic resistance genes (ARGs) in aquaculture systems. Although the recirculating systems have been considered as a promising approach for preventing the coastal water pollution of antibiotics ...
Jianhua Wang, Lu J(吕剑)
core   +1 more source

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

mLife, EarlyView.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei, Yawen Cai, Jianfeng Huang, Kedong Zhao, Zuqin Zhang, Dandan Yu, Shiyan Lu, Zeying Lai, Thomas K. Wood, Xinmiao Fu   +9 more
wiley   +1 more source

Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia

Antimicrobial Resistance and Infection Control, 2017
Background Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance to these classes of antimicrobials has increased significantly in the recent years.
Tadesse Eguale, Josephine Birungi, Daniel Asrat, Moses N. Njahira, Joyce Njuguna, Wondwossen A. Gebreyes, John S. Gunn, Appolinaire Djikeng, Ephrem Engidawork   +8 more
doaj   +1 more source

Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids

Acta Chimica Slovenica, 2020
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate
David Milićević, Roman Kimmel, Damijana Urankar, Andrej Pevec, Janez Košmrlj, Stanislav Kafka   +5 more
doaj   +1 more source

Quorum sensing communication between bacteria and human cells: signals, targets, and functions [PDF]

, 2014
Both direct and long-range interactions between pathogenic Pseudomonas aeruginosa bacteria and their eukaryotic hosts are important in the outcome of infections. For cell-to-cell communication, these bacteria employ the quorum sensing (QS) system to pass
Angelika Holm, Elena Vikström
core   +2 more sources