Results 61 to 70 of about 61,740 (193)
Food Safety and Health, EarlyView.ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei +4 more
wiley +1 more source
Synthesis and Antimicrobial Activity of Novel 4-Hydroxy-2-quinolone Analogs
Molecules, 2020 Alkyl quinolone has been proven to be a privileged scaffold in the antimicrobial drug discovery pipeline. In this study, a series of new 4-hydroxy-2-quinolinone analogs containing a long alkyl side chain at C-3 and a broad range of substituents on the C ...
Thitiphong Khamkhenshorngphanuch +7 more
doaj +1 more source
Argentine plant extracts active against polymerase and ribonuclease H activities of HIV-1 reverse transcriptase [PDF]
, 1999 Lipophilic and hydrophilic extracts of four Argentine plants (Gamochaeta simplicaulis Cabr. 1, Achyrocline flaccida Wein. D. C. 2, Eupatorium buniifolium H. et A. 3, and Phyllanthus sellowianus Muell. Arg.
Broussalis, A. (Adriana) +13 more
core
Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target [PDF]
, 2014 YesN-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases offers non-antibiotics-based therapeutic potentials against QS-mediated bacterial
A Dürig +46 more
core +2 more sources
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
Interdisciplinary Medicine, EarlyView.A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
ミカン科Xanthoxylum属植物のアルカロイド研究 [PDF]
, 1961 京都大学0048新制・課程博士薬学博士薬博第18号新制||薬||8(附属図書館)271京都大学大学院薬学研究科薬学専攻(主査)教授 富田 真雄, 教授 上尾 庄次郎, 教授 井上 博之学位規則第5条第1項該当Kyoto ...
石井, 永
core
Journal of Clinical Laboratory Analysis, EarlyView.The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou +8 more
wiley +1 more source
Metabolites, 2020 Pseudomonas aeruginosa is a ubiquitous environmental bacterium that causes chronic infections of burn wounds and in the lungs of cystic fibrosis (CF) patients.
Andrew C. Lybbert +4 more
doaj +1 more source
Determination of liposome/water partition coefficients of organic acids and bases by solid-phase microextraction [PDF]
, 2002 The extraction of two methylated anilines and three chlorinated phenols by solid-phase microextraction (SPME) fibers coated with polyacrylate was investigated as a function of pH.
Berg, M +6 more
core +2 more sources
Journal of Hospital Medicine, EarlyView.Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi +4 more
wiley +1 more source