Results 81 to 90 of about 61,740 (193)

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Simultaneous Quantification of Limonin, Two Indolequinazoline Alkaloids, and Four Quinolone Alkaloids in Evodia rutaecarpa (Juss.) Benth by HPLC-DAD Method

Journal of Analytical Methods in Chemistry, 2013
A simple and efficient HPLC-DAD (225 nm) method was developed and validated for the simultaneous determination of limonin and six key alkaloids (evodiamine, rutaecarpine, 1-methyl-2-undecyl-4(1H)-quinolone, evocarpine, 1-methy-2-[(6Z,9Z)]-6,9 ...
Pei-ting Zhang, Bi-yan Pan, Qiong-feng Liao, Mei-cun Yao, Xin-jun Xu, Jin-zhi Wan, Dan Liu, Zhi-yong Xie   +7 more
doaj   +1 more source

Acceleration of pro-caspase-3 maturation and cell migration inhibition in human breast cancer cells by phytoconstituents of Rheum emodi rhizome extracts [PDF]

, 2013
The aggressive nature of estrogen receptor (ER)-negative breast cancer subtype obligates for innovative targeted therapies. The present study aimed to investigate the phytoconstituents and specific anticancer activities of Rheum emodi rhizome, a known ...
Cijo George, V., Kumar, R. Ashok, Naveen Kumar, D. R., Suresh, P. K.   +3 more
core  

A genomic island integrated into recA of Vibrio cholerae contains a divergent recA and provides multi-pathway protection from DNA damage [PDF]

, 2014
© 2015 Society for Applied Microbiology and John Wiley & Sons Ltd. Lateral gene transfer (LGT) has been crucial in the evolution of the cholera pathogen, Vibrio cholerae.
Charles, IG, Islam, A, Labbate, M, Monahan, LG, Mutreja, A, Rapa, RA, Stokes, HW, Thomson, N   +7 more
core   +2 more sources

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

Veterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker, Dan O'Neill, Huw Stacey, Dave Brodbelt   +3 more
wiley   +1 more source

Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels [PDF]

, 2018
As one of the major pathogens in wound infections, Pseudomonas aeruginosa produces several virulence factors and forms biofilms; these processes are under the regulation of various quorum sensing (QS) systems.
Coenye, Tom, Crabbé, Aurélie, Kaever, Volkhard, Sass, Andrea, Van Acker, Heleen, Van Nieuwerburgh, Filip, Verhasselt, Bruno, Wille, Jasper, Zhang, Yunhui   +8 more
core   +3 more sources

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

Veterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth, Patricia Mayer, Annemarie Käsbohrer, Tanja Tripolt, Klemens Fuchs   +4 more
wiley   +1 more source

Detection and molecular characterization of multiresistant Enterobacteriaceae carried by houseflies in the city of Bobo-Dioulasso, Burkina Faso [PDF]

International Journal of One Health
Background and Aim: Houseflies (Musca domestica) are synanthropic insects that are vectors of a wide range of multidrug-resistant pathogens responsible for infectious diseases.
Sanou D. M. Soufiane, Yerbanga R. Serge, Bangre Tinlé, N’Do Sévérin, Kaboré N. Firmin, Traoré Isidore, Zoungrana Jacques, Yaméogo Inès, Nikiéma Félicité, Fofana Aminata, Batiéné Naomi, Ouédraogo Jean-Bosco, Sangaré Ibrahim, Sanou Mahamoudou   +13 more
doaj   +1 more source

Comparative in-vitro activity of new quinolones against clinical isolates and resistant mutants [PDF]

, 2017
The in-vitro activity of five new fluoroquinolones, WIN 57273, sparfloxacin, flerox-acin, temafloxacin and tiprofloxacin was determined against 543 recent clinical isolates and eight quinolone resistant strains derived by mutation and their five parent ...
Auckenthaler, R., Lew, D. P., Pechère, J.-C, Peebo, M., Rohner, P.   +4 more
core  

Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population‐Based Registry Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill, Marleen M. H. J. van Gelder, Hilde M. Engjom, Hedvig M. E. Nordeng   +3 more
wiley   +1 more source