Results 91 to 100 of about 32,766 (293)
(E)-1-(2-Aminophenyl)-3-(4-chlorophenyl)prop-2-en-1-one [PDF]
, 2016 The title chalcone (E)-1-(2-aminophenyl)-3-(4-chlorophenyl)prop-2-en-1-one was prepared with an excellent yield from a Claisen–Schmidt condensation reaction between o-aminoacetophenone and p-chlorobenzaldehyde.
Abonia, Rodrigo +5 more
core +2 more sources
Medicinal Research Reviews, EarlyView.ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra +3 more
wiley +1 more source
Synthesis and Anticancer Activity of 3,4-Diaryl-1,2-dihydro- and 1,2,3,4-Tetrahydroquinolines
MoleculesTetrahydroquinolines are key structures in a variety of natural products with diverse pharmacological utilities and other applications. A series of 3,4-diaryl-5,7-dimethoxy-1,2,3,4-tetrahydroquinolines were synthesized in good yield by reacting 3-aryl-5 ...
Santosh Rajput +4 more
doaj +1 more source
Highly Enantioselective Catalytic Addition of Grignard Reagents to N-Heterocyclic Acceptors [PDF]
, 2019 General methods to prepare chiral N-heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2- and 4 ...
Guo, Yafei, Harutyunyan, Syuzanna R.
core +2 more sources
ChemistryOpen, EarlyView.Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas +4 more
wiley +1 more source
E-Journal of Chemistry, 2011 Quinolone are a class of potent broad-spectrum antibacterial drugs that target the bacterial type II DNA topoisomerases (DNA gyrase) and topoisomerase IV.
Eskandar Alipour +6 more
doaj +1 more source
Laboratory Survey of Fluoroquinolone Activity [PDF]
, 2017 Fluoroquinolones are active against a wide variety of bacteria. The antibacterial spectra of fluoroquinolones encompass staphylococci, Bacillus species, and Corynebacterium species implicated in infections of the immunocompromised host ...
Bellido, Francis, Pechère, Jean-Claude
core
Mitochondrial dynamics in autoimmune diseases
Rheumatology &Autoimmunity, EarlyView.Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma +5 more
wiley +1 more source
Quinolone-resistant Escherichia coli [PDF]
, 2008 Quinolones (nalidixic acid - NAL, norfloxacin - NOR, ciprofloxacin - CIP and gatifloxacin - GAT) were tested against Escherichia coli isolated from urine (385 patient samples) by disk diffusion (DD) and agar dilution (AD) methods. Fifty-three samples (13.
Dalla Costa, Libera Maria +4 more
core +2 more sources
Small, EarlyView.This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales +10 more
wiley +1 more source