Results 71 to 80 of about 11,679,551 (275)

Reaction of aryne with aza-Morita–Baylis–Hillman adducts: Synthesis of 4-quinolones and N-arylation products

Journal of Saudi Chemical Society, 2017
The reaction of aryne with aza-Morita–Baylis–Hillman (aza-MBH) adducts has been studied. Aryne reacts with aza-MBH adducts through a cascade insertion–cyclization–ene reaction to produce 4-quinolones in 18–44% yields; meanwhile, aza-MBH adducts undergo N-
Li-Li Liu, Zhi-Juan Li, Cheng-Zhi Gu, Lin He, Bin Dai   +4 more
doaj   +1 more source

Discovery of N -quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents [PDF]

, 2022
Wenjie Xue, Yaling Wang, Xu Lian, Xueyao Li, Jing Pang, Johannes Kirchmair, Kebin Wu, Zunsheng Han, Xuefu You, Hongmin Zhang, Jie Xia, Song Wu   +11 more
openalex   +1 more source

Molecular Layer Deposition for Surface Modification of Emerging Battery Systems

EcoEnergy, EarlyView.
This review provides a timely and comprehensive survey on the applications of molecular layer deposition (MLD) in surface modifications of emerging battery systems, including lithium‐ion batteries (LIBs), lithium metal batteries (LMBs), sodium‐based batteries (NBs), and solid‐state batteries (SSBs).
Xiangbo Meng
wiley   +1 more source

Development of Silver Nanoparticles-Based Sensor for Detection of Quinolones by Surface-Enhanced Raman Spectroscopy: a Case-Study Using Levofloxacin

Chemical Engineering Transactions, 2016
Numerous studies have shown that a variety of pharmaceuticals such as quinolones have been detected in the vicinity of municipal wastewater discharges and livestock agricultural facilities.
N.V. Madalossi, I.O. Mazali, F.C.A. Corbi, F.A. Sigoli, E. Santos   +4 more
doaj   +1 more source

Efficient synthesis of novel N-substituted 2-carboxy-4-quinolones via lithium bis(trimethylsilyl)amide (LiHMDS)-induced in situ cyclocondensation reaction

, 2017
A different approach for the synthesis of N-substituted 2-carboxy-4-quinolones using direct reductive amination followed by LiHMDS-induced cyclocondensation has been developed.
Phool Hasan, Babita Aneja, M. M. Masood, Md. Belal Ahmad, U. Yadava, C. Daniliuc, M. Abid   +6 more
semanticscholar   +1 more source

Medicare Part D and Hospital Admissions due to Antimicrobial Resistance

Health Economics, EarlyView.
ABSTRACT Antimicrobial resistance (AMR) has been increasing rapidly in the United States despite government efforts to contain its spread. Both under‐utilization and overuse of prescribed antimicrobials contribute to rising resistance. The introduction of Medicare Part D in 2006 expanded prescription drug coverage for the elderly, including coverage ...
Ricardo B. Ang III
wiley   +1 more source

Engineered Biosynthesis of Fungal 4-Quinolone Natural Products

Organic Letters, 2020
Quinolone-containing natural products are widely found in bacteria, fungi, and plants. The fungal quinolactacins, which are N-methyl-4-quinolones, display a wide spectrum of biological activities. Here we uncovered a concise nonribosomal peptide synthetase pathway involved in quinolactacin A biosynthesis from Penicillium by using heterologous ...
Mengting Liu, Masao Ohashi, Yi Tang
openaire   +3 more sources

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Potentials of N-(2, 4-dinitro-1-naphthyl)-p-toluenesulphonamide and 2, 4-dinitro-1-naphthol as novel charge transfer acceptors in pharmaceutical analysis of some quinolones and cephalosporins

Future Journal of Pharmaceutical Sciences, 2022
Background Quinolones and cephalosporins are antibiotic agents with activity against Gram-positive and Gram-negative bacteria. They contain chromophores and amine groups which are electron-rich centres capable of donating electrons to electron-deficient ...
O. E. Umoh, O. A. Adegoke, D. E. Effiong
doaj   +1 more source

Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide [PDF]

, 2011
BACKGROUND: "Nubiotics" are synthetic oligonucleotides and nucleotides with nuclease-resistant backbones, and are fully protonated for enhanced ability to be taken up by bacterial cells.
Lun-Quan Sun, Ming Wang, Shanping Cao
core   +2 more sources