Antimicrobial activity of 1, 3, 4-thiadiazole derivatives: a recent review [PDF]
Journal of Applied Pharmaceutical Research, 2018 A few five members’ aromatic systems having three hetero-atoms at symmetrical positions, for example, thiadiazoles have been considered broadly attributable to their intriguing pharmacological properties.
Alam, Faruk
core +6 more sources
A Convenient route for the synthesis of antimicrobial 1, 3, 4- thiadiazole derivatives
Bibechana, 2012 Thiosemicarbazide of 6-chloro-2- aminobenzothiazole on cyclization with different aromatic carboxylic acids in Phosphorus oxychloride provided the corresponding 2-aryl-5-(6’-chloro-1’,3’-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles 4a-j. The compounds
AD Mishra
doaj +5 more sources
Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles [PDF]
Journal of Sciences, Islamic Republic of Iran, 2009 A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n)
S.D. Srivastava
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Synthesis and anticancer activity of some novel 3-(1, 3, 4-thiadiazol-2-yl)-quinazolin-4-(3H)-ones [PDF]
Orbital: The Electronic Journal of Chemistry, 2010 Quinazolinone is a versatile lead molecule for designing potential bioactive agents. The compounds that have quinazolin-4-ones moiety are associated with interesting biological activities such as antifungal, antibacterial, antiviral, antitubercular and ...
Alex Joseph +6 more
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Synthesis and Biological Evaluation of Some Newer 1H-Benzo[b][1,5]diazepin-2(3H)-one Derivatives as Potential Anticonvulsant Agents [PDF]
Pharmaceutical Sciences, 2022 Background: Regardless of the availability of all novel and earlier treatments, seizure control is notoriously complicated. In the hopes of discovering the latest and ultimate therapy, medicinal chemists will keep on to hunt for new antiepileptic ...
Dinesh D Rishipathak +2 more
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Фармацевтичний журнал, 2021 One of the promising methods of creating antitumor drugs is the screening of potential antitumor agents among synthesized compounds. Nitrogen-based heterocycle analogues are an extremely important class of organic substances that are widely used in ...
I. І. Myrko +4 more
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Synthesis and Diuretic Activity of Substituted 1,3,4-Thiadiazoles
Scientifica, 2022 1,3,4-Thiadiazole nuclease, a 5-membered heterocyclic ring system containing two nitrogen and one sulfur atoms in addition to carbon atoms, is compound that showed promising results in the process of searching new diuretic agents. In this study, seven 5-
Asrat Ergena +2 more
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PHARMACOLOGICAL ACTIVITY OF 5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1538), 2‐AMINO‐5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1460) AND 2‐AMINO‐5‐(2‐THIENYL)‐1: 3: 4‐THIADIAZOLE (L 1458) [PDF]
British Journal of Pharmacology and Chemotherapy, 1958 The pharmacological actions of 5‐phenyl‐1: 3: 4‐thiadiazole (L 1538), 2‐amino‐5‐phenyl‐1: 3: 4‐thiadiazole (L 1460) and 2‐amino‐5‐(2′‐thienyl)‐1: 3: 4‐thiadiazole (L 1458) have been studied and compared with those of other muscular relaxant drugs. The three compounds have paralysing effects in mice, rats, cats, and dogs.
G, MAFFII, E, SONCIN
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Molecules, 2023 Palladium-catalyzed direct (het)arylation reactions of strongly electron-withdrawing tricyclic benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) and its 4,8-dibromo derivative were studied; the conditions for the selective formation of mono- and bis-aryl ...
Timofey N. Chmovzh +3 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022 Synthesis and structural modification of azoles remains an important area of medical chemistry and allows to obtain new compounds with a wide range of biological activity.
О. V. Kholodniak +2 more
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