Results 21 to 30 of about 12,533,127 (227)

Synthesis of New 4-Vinyl-1,2,3-Thiadiazoles

, 2021
Simple and convenient methods for the synthesis of a range of new 1,2,3-thiadiazole derivatives, including ethyl esters, alcohols, and aldehydes, were developed.
Sinead T Keaveney (20250621), Marina A Tokareva (20250615), Tatiana V Glukhareva (20250618), Barbara A Messerle (20251236), Indrek Pernik (1353273)   +4 more
core   +1 more source

Biological activity of heterocyclic systems based on functionally substituted 1,3,4-thia(oxa)diazoles (a review)

Фармацевтичний журнал, 2019
1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj   +1 more source

Synthesis and Evaluation of Antimicrobial Activity of 1, 3, 4-Thiadiazole Analogues for Potential Scaffold

Journal of Pharmacopuncture, 2021
Pathogenic microbes are causal agents for various types of severe and even lethal infectious diseases. Despite of development in medication, bacterial and fungal infections still persist to be a vital problem in health care. Bacteria and several fungal species have shown resistance to antibiotics used in treatment to current medications.
Sagar Sahu, Tanesh Sahu, Gunjan Kalyani, Bina Gidwani   +3 more
openaire   +4 more sources

Visible-light-induced intramolecular C–S bond formation for practical synthesis of 2,5-disubstituted 1,3,4-thiadiazoles

, 2022
A general and facile visible-light mediated protocol for the synthesis of 2-arylamino-5-aryl-1,3,4- thiadiazoles via one-pot condensation and intramolecular C–S coupling cascade reaction has been developed.
Ruohan Li (6490004), Shouri Sheng (2880404), Haishan Wei (14195173), Junmin Chen (625300), Wenqing Lan (14195170), Zhaocheng Shi (14195167)   +5 more
core   +1 more source

Synthesis Of 2-Benzamidomethyl-5-Substituted Amino-1,3,4-Thiadiazoles-2,5-Disubstituted 1,3,4-Oxadiazole and 4,5-Disubstituted 1,2,4-Triazole-3-Thiol [PDF]

مجلة التربية والعلم, 2012
In this paper the synthesis of some substituted 1,3,4-oxadiazoles , 1,3,4-thiadiazoles and 1,2,4-triazoles starting from amino acid and benzoyl chloride is reported.
K. M. Daoud, A. N. Ali, A. A. Ahmed
doaj   +1 more source

Synthesis and Antifungal Activity of N-(3-(4-(1,3-dioxolan-2-yl) phenyl)-1,2,4-thiadiazol-5-yl) Benzamide Derivatives: An in-vitro Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Fungal infections are associated with morbidity and mortality globally and immense economic burden. With the emergence of multidrug resistant fungal strains, it is essential to develop new antifungal drugs.
K Dayana, Raja Mohamed Kamil, MR Manasa, Santhosh M Mathews   +3 more
doaj   +1 more source

A Nano-MgO and Ionic Liquid-Catalyzed 'Green' Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51). [PDF]

PLoS ONE, 2015
In this work, we describe the 'green' synthesis of novel 6-(adamantan-1-yl)-2-substituted-imidazo[2,1-b][1,3,4]thiadiazoles (AITs) by ring formation reactions using 1-(adamantan-1-yl)-2-bromoethanone and 5-alkyl/aryl-2-amino1,3,4-thiadiazoles on a nano ...
Sebastian Anusha, Baburajeev Cp, Chakrabhavi Dhananjaya Mohan, Jessin Mathai, Shobith Rangappa, Surender Mohan, Chandra, Shardul Paricharak, Lewis Mervin, Julian E Fuchs, Mahedra M, Andreas Bender, Basappa, Kanchugarakoppal S Rangappa   +13 more
doaj   +1 more source

Extending El Sayed's Rule by 1(n,π*)–3(n,π*) Rotation via Intramolecular Secondary Interaction Enables Room‐Temperature Circularly Polarized Phosphorescence in Solution

Angewandte Chemie, EarlyView.
Weak but skilled: Our results highlight the crucial role of intramolecular secondary interactions to induce an efficient ISC between formally identical 1(n,π*) and 3(n,π*) states in chiral thionated phthalimide derivatives. This unprecedented type of inter‐system crossing (ISC) extends the usual thinking of the El‐Sayed principle and enables the ...
Oscar Charpentier, Marie Guesdon, Catherine Demangeat, Maher Hojorat, Joseph Young, Emrys W. Evans, Vincent Dorcet, Nicolas Galland, Denis Jacquemin, Ludovic Favereau   +9 more
wiley   +2 more sources

Syntheses of Diheterocyclic Compounds Based on 2-Thioacetohydrazide-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine

Molecules, 2008
The syntheses of some diheterocyclic compounds from 2-thioacetohydrazide- 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (1) are described. Compound 1 can be converted into triazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles.
Guang-Fu Yang, Hai-Yang Tu, Chao-Nan Chen, Qiong Chen, Zu-Ming Liu   +4 more
doaj   +1 more source

Electrochemical Oxidative Intramolecular N–S Bond Formation: Synthesis of 3‑Substituted 5‑Amino-1,2,4-Thiadiazoles

, 2020
A facile and efficient protocol for the synthesis of 3-substituted 5-amino-1,2,4-thiadiazoles has been developed through the electro-oxidative intramolecular dehydrogenative N–S bond formation of imidoyl thioureas.
Kun Liu, Kun Liu (148201), Jiaqi Zhang (412762), Tao Yang, Lijun Li (406691), Liping Hu, Liping Hu (172765), Zan Yang, Congshan Zhou, Congshan Zhou (1923325), Zan Yang (5513243), Jiaqi Zhang, Tao Yang (184280), Lijun Li   +13 more
core   +1 more source