Synthesis and Diuretic Activity of Substituted 1,3,4-Thiadiazoles
Scientifica, 2022 1,3,4-Thiadiazole nuclease, a 5-membered heterocyclic ring system containing two nitrogen and one sulfur atoms in addition to carbon atoms, is compound that showed promising results in the process of searching new diuretic agents. In this study, seven 5-
Asrat Ergena +2 more
doaj +2 more sources
A Convenient route for the synthesis of antimicrobial 1, 3, 4- thiadiazole derivatives
Bibechana, 2012 Thiosemicarbazide of 6-chloro-2- aminobenzothiazole on cyclization with different aromatic carboxylic acids in Phosphorus oxychloride provided the corresponding 2-aryl-5-(6’-chloro-1’,3’-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles 4a-j. The compounds
AD Mishra
doaj +5 more sources
NOVEL HETEROCYCLES BASED ON 1, 3, 4-THIADIAZOLE SCAFFOLD AS INSECTICIDES [PDF]
Journal of Environmental Science, 2017 The crop plants are the major source of human nutrition, but insects and pests cause huge economic losses every year. The authors were interested in developing novel insecticidal agents with low toxicity and an acceptable impact on the environment. Thus,
Madkour, H. F +3 more
doaj +2 more sources
Synthesis and Biological Evaluation of Some Newer 1H-Benzo[b][1,5]diazepin-2(3H)-one Derivatives as Potential Anticonvulsant Agents [PDF]
Pharmaceutical Sciences, 2022 Background: Regardless of the availability of all novel and earlier treatments, seizure control is notoriously complicated. In the hopes of discovering the latest and ultimate therapy, medicinal chemists will keep on to hunt for new antiepileptic ...
Dinesh D Rishipathak +2 more
doaj +1 more source
Фармацевтичний журнал, 2021 One of the promising methods of creating antitumor drugs is the screening of potential antitumor agents among synthesized compounds. Nitrogen-based heterocycle analogues are an extremely important class of organic substances that are widely used in ...
I. І. Myrko +4 more
doaj +1 more source
Molecules, 2023 Palladium-catalyzed direct (het)arylation reactions of strongly electron-withdrawing tricyclic benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) and its 4,8-dibromo derivative were studied; the conditions for the selective formation of mono- and bis-aryl ...
Timofey N. Chmovzh +3 more
doaj +1 more source
SYNTHESIS AND ANTIBACTERIAL TESTING OF SOME NEW SELENADIAZOLE AND THIADIAZOLE CONTAINING AMINO ACID MOIETIES [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1986 Several 4-{4-(substitutedglycylamino)-phenyl}-1,2,3-selenadiazols (IV) and 4{4-(substitutedglycylamino)phenyl}-1,2,3-thiadiazoles (V) were prepared for evaluation of their antimicrobial activity.
A. Ahmed, M. Abd-Alla, B. Bayoumi
doaj +1 more source
PHARMACOLOGICAL ACTIVITY OF 5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1538), 2‐AMINO‐5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1460) AND 2‐AMINO‐5‐(2‐THIENYL)‐1: 3: 4‐THIADIAZOLE (L 1458) [PDF]
British Journal of Pharmacology and Chemotherapy, 1958 The pharmacological actions of 5‐phenyl‐1: 3: 4‐thiadiazole (L 1538), 2‐amino‐5‐phenyl‐1: 3: 4‐thiadiazole (L 1460) and 2‐amino‐5‐(2′‐thienyl)‐1: 3: 4‐thiadiazole (L 1458) have been studied and compared with those of other muscular relaxant drugs. The three compounds have paralysing effects in mice, rats, cats, and dogs.
G, MAFFII, E, SONCIN
openaire +2 more sources
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW N-ETHYL-N-METHYL BENZENE SULFONAMIDE DERIVATIVES [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2014 This article describes the synthesis of some novel sulfonamide having the biologically active hydrazones 1,3,4-thiadiazoles and 4-oxothiazolidines moieties 2-4, 7 and 10-13 respectively. Starting with 4-acetyl-N-ethyl-N-methyl benzene sulfonamide (
Ahmed El-Morsy
doaj +1 more source
Synthesis of Some Substituted 1,3,4-Oxadiazoles, Thiadiazoles and 1,2,4-Triazoles from Acid Chlorides [PDF]
مجلة التربية والعلم, 2013 The conversion of some acid chlorides to substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. Benzoyl chloride and 4- nitrobenzoyl chloride were treated with hydrazine hydrate in ethanol to give acid hydrazides (1,2), The ...
E. Q. Mahmood, O. Th. Ali, K. M. Daoud
doaj +1 more source