Results 31 to 40 of about 9,296,901 (229)

2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses

Acta Pharmaceutica, 2020
Parasitic diseases are a serious public health problem affecting hundreds of millions of people worldwide. African trypanosomiasis, American trypanosomiasis, leishmaniasis, malaria and toxoplasmosis are the main parasitic infections caused by protozoan ...
Serban Georgeta
doaj   +1 more source

4-Bromobenzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)

Molbank, 2022
Bromoderivatives of benzofused 1,2,5-thiadiazoles are important precursors for the synthesis of dyes, which are widely used to design effective photovoltaic materials.
Timofey N. Chmovzh, Daria A. Alekhina, Timofey A. Kudryashev, Oleg A. Rakitin   +3 more
doaj   +1 more source

The Acid and/or Thermal Mediated Ring Contraction of 4H‑1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazoles

, 2016
A near-quantitative acid and/or thermal mediated ring contraction of 3′,5′-diarylspiro­(benzo­[d]­[1,3]­dioxole-2,4′-[1,2,6]­thiadiazines) affords 3-aryl-4-(2-arylbenzo­[d]­[1,3]­dioxol-2-yl)-1,2,5-thiadiazoles.
Andreas Kourtellaris (1693780), Panayiotis A. Koutentis (1278807), Andreas S. Kalogirou (1546180)   +2 more
core   +1 more source

A convenient, rapid microwave assisted synthesis of some novel 3-[(4-chloro-3-methylphenoxy)methyl]-6-aryl-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles using acidic alumina

Journal of Saudi Chemical Society, 2010
A facile synthesis of 3-[(4-chloro-3-methylphenoxy)methyl]-6-aryl-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 3a–n has been achieved by microwave promoted condensation of 3-mercapto-4-amino-5-[(4-chloro-3-methylphenoxy)methyl]-4H-1,2,4-triazole
Jignesh P. Raval, Hemul V. Patel, Pradip S. Patel, Kishor R. Desai   +3 more
doaj   +1 more source

Synthesis of New 4-Vinyl-1,2,3-Thiadiazoles

, 2021
Simple and convenient methods for the synthesis of a range of new 1,2,3-thiadiazole derivatives, including ethyl esters, alcohols, and aldehydes, were developed.
Sinead T Keaveney (20250621), Marina A Tokareva (20250615), Tatiana V Glukhareva (20250618), Barbara A Messerle (20251236), Indrek Pernik (1353273)   +4 more
core  

Synthesis under Microwave Irradiation of [1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazoles and Other Diazoles Bearing Indole Moieties and Their Antimicrobial Evaluation

Molecules, 2011
Microwave-assisted synthesis of some novel compounds, namely, 3-(2-methyl-1H-indol-3-yl)-6-aryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 5a,b was accomplished via bromination of 2-methyl-3-[4-(arylideneamino)-5-mercapto-4H-[1,2,4]triazol-3-yl]-1H ...
Sobhi M. Gomha, Sayed M. Riyadh
doaj   +1 more source

I2/DMSO-Catalyzed Transformation of N-tosylhydrazones to 1,2,3-thiadiazoles

Frontiers in Chemistry, 2020
An iodine/DMSO catalyzed selective cyclization of N-tosylhydrazones with sulfur without adding external oxidant was developed for the synthesis of 4-aryl-1,2,3-thiadiazoles.
Weiwei Li, Jun Zhang, Jing He, Liang Xu, Luigi Vaccaro, Ping Liu, Yanlong Gu   +6 more
doaj   +1 more source

Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
A novel series of 12 antipyrine derivatives containing 1,3,4-oxadiazoles (4a-d), 1,3,4-thiadiazoles (6a-d), and pyrimidines (8a-d), was preparedand assessed for its potential in vitro COX-2 inhibitors.
Mohammad M. Al-Sanea, Abdelrahman Hamdi, Simone Brogi, Samar S. Tawfik, Dina I. A. Othman, Mahmoud Elshal, Hidayat Ur Rahman, Della G. T. Parambi, Rehab M. Elbargisy, Samy Selim, Ehab M. Mostafa, Ahmed A. B. Mohamed   +11 more
doaj   +1 more source

A Proline‐Integrated Donor–Acceptor Fluorophore: Water‐Vapor‐Responsive Mechanochromic Luminescence and Latent Fingerprint Visualization

Advanced Optical Materials, EarlyView.
A proline‐integrated donor–acceptor fluorophore enables multifunctional luminescence through rational molecular design. Water‐vapor‐responsive mechanochromic luminescence (MCL) with circularly polarized luminescence (CPL) switching and efficient visualization of latent fingerprints (LFPs) are realized from this single small organic molecule.
Hao Chen, Kazuki Kato, Yoshitane Imai, Suguru Ito   +3 more
wiley   +1 more source

Multicomponent Coupling Reactions of Two N‑Tosyl Hydrazones and Elemental Sulfur: Selective Denitrogenation Pathway toward Unsymmetric 2,5-Disubstituted 1,3,4-Thiadiazoles

, 2016
A copper-mediated, three-component reaction between two different N-Ts hydrazones and elemental sulfur was developed, leading to a series of unsymmetric 2,5-disubstituted 1,3,4-thiadiazoles in moderate yields with good functional group compatibility ...
Jiangfei Chen (1446982), En Yao (3182790), Zhen Zhou (184390), Jiang Cheng (1446988), Yang Liu (4829)   +4 more
core   +1 more source