Novel isochroman-triazoles and thiadiazole hybrids: Design, synthesis and antimicrobial activity
In this study, new isochroman-triazole (6a–e) and thiadiazole (7a–e) conjugates were obtained by heterocyclization of isochromanyl thiosemicarbazides (5a–e) under basic and acidic catalysis respectively.
Aamer Saeed, Amara Mumtaz
doaj +1 more source
Bazı α -lipoik asit türevi 1,3,4-tiyadiazol bileşiklerinin sentezi, karakterizasyonu ve antioksidan aktivitelerinin incelenmesi [PDF]
Bu tez çalışmasında, kimyanın pek çok alanında olduğu gibi, özellikle endüstride, tıp ve eczacılıkta geniş kulanım alanlarına sahip olan 1,3,4-tiyadiazol bileşiklerinden, α-lipoik asit türevi tiyadiazol bileşikleri sentezi, karakterizasyonu ve ...
Mohammed Alı Abraheem, Ashweeqı
core +1 more source
Design of Terpene‐Based Eco‐Friendly Solution Process for High‐Performance Organic Solar Cells
High‐performance, terpene‐processed organic solar cells (OSCs) by designing a new green co‐solvent system consisting of eucalyptol (Eu) and 2‐methyltetrahydrofuran (MeTHF) are developed. The OSCs processed from the optimal ratio of Eu and MeTHF achieve the highest power conversion efficiency (PCE) value of 17.3% reported to date for terpene‐processed ...
Hyerin Jeon +3 more
wiley +1 more source
New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
doaj +1 more source
Synthesis and Invitro Anti-Cancer Evaluation of Disubstituied 1,2,4 Thiadmzole Derivatives [PDF]
INTRODUCTION: Chemistry is a very broad subject, and can justly claim to encompass many aspects of the study of biological molecules. To most researchers in the cancer fields, the term ‘chemistry’ is often used in a much narrower way and is synonymous ...
Shalini, S
core
Recent advances in the development of tissue transglutaminase (TG2) inhibitors [PDF]
Tissue transglutaminase (TG2) is a Ca2+-dependent enzyme and probably the most ubiquitously expressed member of the mammalian transglutaminase family. TG2 plays a number of important roles in a variety of biological processes.
Badarau, Eduard +2 more
core +1 more source
Synthesis, crystal structure, DFT and molecular docking studies of N-acetyl-2,4-[diaryl-3-azabicyclo[3.3.1]nonan-9-yl]-9-spiro-4'-acetyl-2'-(acetylamino)-4',9-dihydro-[1',3',4']-thiadiazoles: A potential SARS-nCoV-2 Mpro (COVID-19) inhibitor. [PDF]
Rajamanickam R +4 more
europepmc +1 more source
Synthesis, Characterization and Biological Activity of Some New 4-Substituted-phenyl-3-chloro-1-{5-[(3, 5-dimethyl-1H-pyrazol-1- yl) methyl]-1, 3, 4-thiadiazol-2-yl} azetidin-2-one [PDF]
A new series of 3,5-dimethyl-1H-pyrazole derivatives (1-15) incorporated into fused to different nitrogen and sulphur containing heterocyclic were prepared from 3,5-dimethyl-1H-pyrazole when treated with ethylchloroacetate in the present of potassium ...
Rafah Fadhil Al-Smaisim
core +2 more sources
A brief review article: Various synthesis and therapeutic importance of 1, 2, 4-triazole and its derivatives. [PDF]
Heterocyclic compounds play an important part in medicinal chemistry. Different derivatives of heterocyclic compounds are useful for the various pharmacological activities.
MAKWANA, ATUL H +2 more
core +2 more sources

