Results 71 to 80 of about 12,533,127 (227)

Recent Developments In Chemistry Of 1,3,4-Thiadiazoles [PDF]

, 2014
The methods of preparation, structure and biological activities of 1,3,4-thiadiazoles are ...
Mahmoud Fawzy Ismail, Mahmoud, Mahmoud Refaee, Ismail, Mahmoud Fawzy, Mahmoud Refaee Mahmoud   +3 more
core   +1 more source

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

BMC Cancer, 2017
Background Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer ...
C. P. Baburajeev, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Daniel J. Mason, Julian E. Fuchs, Andreas Bender, Uri Barash, Israel Vlodavsky, Basappa, Kanchugarakoppal S. Rangappa   +9 more
doaj   +1 more source

FXF‐OMe Is a Stable Tripeptide Motif for Ultra‐Short Peptide Coacervates That Establishes Structure‐Property‐Function Relationships

Small, EarlyView.
Ultra‐short peptides with a minimal sticker‐spacer structure undergo liquid‐liquid phase separation, resulting in condensates with microenvironments controlled by the hydrophobicity of the spacers. The condensates provide an easily tunable and exceptionally stable scaffold for photocatalytic microreactors in aqueous media, where catalysis efficiency is
Samuel Hamroff, Lucas Caire da Silva
wiley   +1 more source

Substituent Effect on the Absorption Spectra of Mesoionic 1, 3, 4-Thiadiazoles

, 1969
Substituent Effect on the Absorption Spectra of Mesoionic 1, 3, 4 ...
P. B. Talukdar, S. K. Sengupta
openaire   +1 more source

Smart molecular design of NIR‐II organic fluorophores through self‐driven iterative evolution, deep learning, and fragment‐based assembly

Smart Molecules, EarlyView.
A smart design strategy for NIR‐II organic fluorophores is proposed by combining self‐driven Iterative evolution, deep Learning, and fragment‐based assembly. This work establishes a broadly applicable approach for molecular design, accelerating the discovery of NIR‐II fluorophores and extending to optoelectronic materials and therapeutic compounds ...
Yu Zhang, Zhubin Hu, Xinyuan Wang, Zhenrong Sun, Yongye Liang, Cheng Zhong, Haitao Sun   +6 more
wiley   +1 more source

Estudo da síntese espectros I.V. e atividade farmacobiológica de 1-acil-4-aril-tiosemicarbazidas e triazóis 3,4,5-trissubstituídos [PDF]

, 1987
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Curso de Pós-Graduação em Físico ...
Peres, Marize Terezinha Lopes Pereira
core  

Mass spectral studies of 3,5-Diamino-1,2,4-thiadiazoles

, 1977
The mass spectra and fragmentation mechanisms of some 5-alkyl(or aryl)amino-3-amino-, 5-amino-3- arylamino-, 3,5-bis(arylamino)-, 4- aryl-3-arylamino-5-imino-4,5-dihydro-, and 3-alkyl(or aryl)amino-4- aryl-5-arylimino-4,5-dihydro-1,2,4-thiadiazoles and ...
KN Rajasekharan, CP Joshua
core   +1 more source

Synthesis and In Vitro Antibacterial Activity of New 2-(1-Methyl-4-nitro-1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles

E-Journal of Chemistry, 2011
In the present study we report the synthesis and antibacterial activity of a new series 2-(1-methyl-4-nitro-1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles (6a-c).
Bahram Letafat, Negar Mohammadhosseini, Ali Asadipour, Alireza Foroumadi   +3 more
doaj   +1 more source

Synthesis and Biological Activity of 3-(2-Furanyl)-6-Aryl-1,2,4-Triazolo[3,4-b]-1,3,4 –Thiadiazoles

Molecules, 2002
3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]
Zi-Yi Zhang, Dong-Yong Chen, Xiang-Yun Nan, Xin-Xiang Lei, Xian-Xing Chen, An-Jiang Zhang, Li-Xue Zhang   +6 more
doaj   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

Analysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi, Jacob T. Theismann, Michael A. Johnson   +2 more
wiley   +1 more source