Results 101 to 110 of about 12,533,127 (227)

Phototherapy Strategies for Cancer Treatment: Mechanisms and Emerging Nanomaterials

Aggregate, Volume 7, Issue 10, October 2026.
Phototherapy offers spatiotemporally controlled cancer treatment by converting light into heat, reactive oxygen species, immune activation, and therapeutic gas release. This review summarizes the mechanisms and emerging nanomaterials for photothermal therapy, photodynamic therapy, photoimmunotherapy, and photo‐gas therapy, emphasizing structure ...
Fan Liu, Jun Huang
wiley   +1 more source

Development of Benzothiophene–Bearing Bis–oxadiazole Derivatives for Potential Anticancer Targets: Evaluation of DFT, ADME–Tox, and In Silico Docking

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Innovative synthesis of a novel benzothiophene–based bis–oxadiazole derivatives. The structural characterization was performed using experimental and theoretical methods. Significant anticancer activity against selected cancer cell lines. Three derivatives showed good activity 7b, 7g and 7i with IC50 values 7.5 ± 1.04 and 9.5 ± 1.01 µg/mL.
Nagaraju Madala, Vishal Sharma, Srilalitha Vinnakota   +2 more
wiley   +1 more source

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

Drug Design, Development and Therapy, 2018
Sobhi M Gomha,1 Mastoura M Edrees,2,3 Zeinab A Muhammad,2 Ahmed AM El-Reedy4 1Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt; 2Department of Organic Chemistry, National Organization for Drug Control and Research (NODCAR ...
Gomha SM, Edrees MM, Muhammad ZA, El-Reedy AA   +3 more
doaj  

Green Acid Mediated Synthesis of Imidazo[1,2‐a]Pyrimidine–Thiazole/1,3,4‐Thiadiazole Hybrids: Design, Characterization and In‐Vitro Biological Evaluation

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A new set of imidazo[1,2‐a]pyrimidine‐thiazole/thiadiazole hybrids were developed through the molecular hybridization concept. The thiazole and thiadiazole derivatives were synthesized using water as a solvent, and the final compounds were synthesized using citric acid as an eco‐friendly catalyst.
Dinesha P, Shivakumar Naik, Udayakumar D, Maithilee S. Dhekale, Sampat Parayya Vibhutimath, Rajkumar Reddy Rajula, Revanasiddappa B.C, Nanditha Bhat, Naveena S. Veeranagaiah   +8 more
wiley   +1 more source

Synthesis of 3-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-6- substituted-s-triazolo[ 3,4-b]-1,3,4- thiadiazoles

, 2002
1953-1956Several 3-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-6-substituted-1,3,4-triazolo[3,4-b]-1,3,4-thiadiazoles have been synthesized and their structures established by elemental analysis and spectral ...
Bin Quan, Jin‐Dong Luo, Dong, Heng-Shan, Heng‐Shan Dong, Luo, Jin-Dong, Quan, Bin   +5 more
core   +1 more source

PolarEyes with enhanced digital imaging, a high‐throughput solution for locating and grading crystals

Journal of Applied Crystallography, Volume 59, Issue 5, Page 1557-1569, October 2026.
An open‐source program for the calculation and visualization of polarization‐derived properties of crystalline material is described, alongside the integration of a polarizing image sensor into a home‐built high‐throughput imaging setup.The long‐range internal order of crystals enables them to exhibit a well known and long‐exploited phenomenon ...
Thomas D. Smith, Alexandra Longcake, Michael J. Hall, Michael R. Probert   +3 more
wiley   +1 more source

Synthesis of 2-(4-bromobenzoylamino)-5- 'aryloxymethyl-1,3 ,4-thiadiazoles

, 2001
422-425Reactions of 4-bromobenzoyl chloride with ammonium thiocyanate first, then with aryloxyacetic acid hydrazides under phase transfer catalysis give 1-aryloxyacetyl-4-(4- bromobenzoyl)-thiosemicarbazides 3a-k.
Li, Zheng, Wang, Xicun, Da, Yuxia, Wang, Xiuchun, Chen, Jichou   +4 more
core  

Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety

Molecules, 2011
2-(6,8-Dibromo-2-methylquinazolin-4-yloxy)-acetohydrazide (4) was prepared by the reaction of 6,8-dibromo-2-methylbenzo-[d][1,3]oxazin-4-one with formamide to afford quinazolinone 2, followed by alkylation with ethyl chloroacetate to give the ester 3 ...
Hosam A. Saad, Nermen A. Osman, Ahmed H. Moustafa   +2 more
doaj   +1 more source

Complex multitrophic species interactions and fitness costs: Intricate consequences of jasmonate and salicylate induced plant defences

Journal of Animal Ecology, Volume 95, Issue 10, Page 1859-1875, October 2026.
This study reveals how long‐term activation of jasmonic and salicylic acid signalling reshapes arthropod communities and plant fitness across seasons. By showing that induced defences generate contrasting outcomes and cascading trade‐offs across trophic levels, it challenges the assumption that induced resistance is uniformly beneficial in natural ...
Mônica F. Kersch‐Becker, Guilherme P. Pinheiro, Thaís S. Schweller, Martin Pareja, Victoria M. Pocius, José R. Trigo, Gustavo Q. Romero   +6 more
wiley   +1 more source

Novel isochroman-triazoles and thiadiazole hybrids: Design, synthesis and antimicrobial activity

Journal of Saudi Chemical Society, 2017
In this study, new isochroman-triazole (6a–e) and thiadiazole (7a–e) conjugates were obtained by heterocyclization of isochromanyl thiosemicarbazides (5a–e) under basic and acidic catalysis respectively.
Aamer Saeed, Amara Mumtaz
doaj   +1 more source