Results 101 to 110 of about 9,296,901 (229)

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

open access: yesDrug Design, Development and Therapy, 2018
Sobhi M Gomha,1 Mastoura M Edrees,2,3 Zeinab A Muhammad,2 Ahmed AM El-Reedy4 1Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt; 2Department of Organic Chemistry, National Organization for Drug Control and Research (NODCAR ...
Gomha SM   +3 more
doaj  

Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety

open access: yesMolecules, 2011
2-(6,8-Dibromo-2-methylquinazolin-4-yloxy)-acetohydrazide (4) was prepared by the reaction of 6,8-dibromo-2-methylbenzo-[d][1,3]oxazin-4-one with formamide to afford quinazolinone 2, followed by alkylation with ethyl chloroacetate to give the ester 3 ...
Hosam A. Saad   +2 more
doaj   +1 more source

Optimization of synthesis of thiadiazoles from 4,4-dimethylthiosemicarbazide

open access: yes, 2022
V sklopu diplomskega dela sem načrtovala sintezo 1,3,4-tiadizolov z uporabo modelnih substratov. Sinteza je potekla z reakcijo med ketonom in 4,4-dimetiltiosemikarbazidom.
Kužnik, Lana
core  

Novel isochroman-triazoles and thiadiazole hybrids: Design, synthesis and antimicrobial activity

open access: yesJournal of Saudi Chemical Society, 2017
In this study, new isochroman-triazole (6a–e) and thiadiazole (7a–e) conjugates were obtained by heterocyclization of isochromanyl thiosemicarbazides (5a–e) under basic and acidic catalysis respectively.
Aamer Saeed, Amara Mumtaz
doaj   +1 more source

Unfused Heterobicycles as Amplifiers of Phleomycin. VII> Some Bithiazoles; Thienyl-, Furanyl- and Thiazolyl-thiadiazoles and Related Oxadiazoles

open access: yes, 1985
Syntheses are described for several unfused heterobicycles including 4,5′- and 2,4′-bithiazoles, 5-(thiazol-4′ and 5′-yl)-1,3,4- thiadiazoles , 5-(thien-2′-yl)-, 5-(furan-2′ and 3′-yl)-, thiadiazoles and related oxadiazoles, all with side chains ...
SJ Sullivan, DJ Brown, WB Cowden
core   +1 more source

Synthesis of new 1, 2, 4-triazolo-thiadiazoles and its 2-oxoazetidines as antimicrobial, anticonvulsant and antiinflammatory agents

open access: yes, 2002
2357-2363Several 2-arylidenylamino-5-(N 1-1,2, 4-triazolomethyl)-1, 3, 4-thiadiazoles 4 and 1-[5'-(N1-1, 2, 4-triazolomethyl) -1', 3', 4'-thiadiazol-2'-yl]-4-(substituted phenyl) -3-chloro-2-oxo-azetidines 5 have been synthesised and evaluated for ...
S. D. Srivastava   +5 more
core   +1 more source

Synthesis and Antimicrobial Activity of New 5-(2-Thienyl)-1,2,4-triazoles and 5-(2-Thienyl)-1,3,4-oxadiazoles and Related Derivatives

open access: yesMolecules, 2010
New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
doaj   +1 more source

Synthesis of newer selenadiazoles and thiadiazoles from their chroman-4-one precursors

open access: yes, 2003
189-191A newer series of 13 compounds viz. 2-aryl-3,4-dihydrobenzopyrano [3,4-d]-1, 2, 3-selenadiazoles 3 and 2-aryl-3,4-dihydrobenzopyrano [3,4-d]-1, 2, 3-thiadiazoles 4 have been synthesized from their chroman-4-one ...
Gaikwad, M S   +4 more
core  

Synthesis and properties of nitrogen-containing 1,2,3-thiadiazoles [PDF]

open access: yes, 2013
Одно из наиболее перспективных направлений в развитии химии гетероциклических соединений представляет собой синтез и изучение химических свойств и биологической активности моно- и бициклических систем на основе 1,2,3-тиадиазолов.
Kalinina, T. A.   +1 more
core  

Recent Advances in the Denitrogenative Annulation Reactions of 1,2,3-Thiadiazoles

open access: yes
1,2,3-Thiadiazoles exhibit versatile reactivity due to their ability to undergo ring cleavage, forming α-diazothione species through a Dimroth-type equilibrium.
Sinead T Keaveney (20250621)   +2 more
core  

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