Results 21 to 30 of about 3,781 (252)

Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana) [PDF]

, 2017
Infectious diseases remain a significant threat to human health, contributing to more than 17 million deaths, annually. With the worsening trends of drug resistance, there is a need for newer and more powerful antimicrobial agents.
A Brüning, A Fodor, A Husain, A Idhayadhulla, A Kaplan, A Nemeikaitė-Čėnienė, A Pantosti, A Pawellek, A Rauf, A Richters, A Rico, A Sakunphueak, AJ Alanis, AM Alanazi, AM Carvalho, AM Griggs, AS Mayhoub, Ayaz Anwar, B Combourieu, B Sadek, B Villemagne, B Zarzycka, BE Bilich, BE Brown, BL Ginsborg, BV Le, C Amutha, C Rademacher, C Shiota, CA Morgan, CH Yen, CL Yuan, CMM Gómez, CT Makowski, D Duś, D Mehetre, D Raffa, D Vergara, DA Pisanenko, DJ Hardick, DT Youssef, E Braud, E Clynen, E Oberbauer, E Pery, E Rosatelli, EA Musad, EC Kormann, EM Flefel, EV Verbitskiy, F Puig-Basagoiti, FN Alvarez, FT Hatch, FZ Mharti, G Devasahayam, G Engelsma, G Liu, G Ramdani, G Ren, G Schlewer, G Şahin, GN Vassilev, H Chikhale, H Hatano, H Hussain, H Istanbullu, H Li, H Niaz, H Smetana, H Wang, HB Shin, HY Chen, I Karakaya, I Orhan, IC Zampini, J Győrfi, J Han, J La, J Mareddy, JD Guzman, JF Sun, JL Vennerstrom, JM Ontoria, JP Rappai, JR Bauquier, JW Weaver, JY Yang, K Iwasa, K Philip, K Tangdenpaisal, K Wada, KW Leal, KW Park, L Sun, LJ Huang, M Akhter, M al-Rashida, M Amiche, M Brunskole Švegelj, M Gökce, M Jahangir, M Ma, M Miyazawa, M Pawelczap, M Sagheer, M Salzet, M Zhu, MA Aziz-ur-Rehman Abbasi, MA Orabi, MC Enright, MD Bachi, MH Metz-Boutigue, MIC De Troconis, MJ Arrowood, MJ Frederico, MM Alam, MM Khafagy, MN Zemtsova, MT Mackmull, Muhammad Raza Shah, N Desplaces, N Mashhoon, N Sunduru, N Özbek, NA Khan, NA Khan, NA Lack, Naveed Ahmed Khan, ND Eddington, NG Anthony, NK Roy, NR Gonewar, O Perwitasari, OO Ajani, OO Peter, P Armati, P Bulet, P Chen, P Deprez, P Funk, P Kumar, P Nordmann, P Samadhiya, PB Savage, Peter J. Heard, PL Taylor, Q Zheng, QC Fu, R Bonnett, R Bonnett, R De Simone, R Ruckli, R Wilson, RA Tapia, RL Groves, Ruqaiyyah Siddiqui, S Antoniou, S Bondock, S Celikler, S Cesarini, S Elliott, S Ganguli, S George, S Indumathi, S Kasai, S Lee, S Minami, S Nagarajan, S Wirth, S Yang, SA Lujan, Salwa Mansur Ali, SC Bang, SC Basak, Seng-Kai Ong, SF Liou, SM Capitosti, T Antonucci, T Ellendorff, T Ishikawa, TB Emran, TC Lima, TC Yang, TES Ali, TP Yin, TR Burke, TS Tiuman, TT Cushnie, TW Sanchez, U Guzzi, U Singh, V Bhardwaj, V Exarchou, V Facchinetti, V Mihailovic, V Miliukienė, VK Bajpai, VV Kouznetsov, VV Kouznetsov, W He, X He, XD Wang, XJ Gao, XN Wang, XP Sun, Y Dai, Y Fang, Y Girard, Y Take, Y Tang, Y Zhao, Y Özkay, YH Seo, YLN Murthy, YM Sinam, Z Su   +215 more
core   +1 more source

NOVEL HETEROCYCLES BASED ON 1, 3, 4-THIADIAZOLE SCAFFOLD AS INSECTICIDES [PDF]

Journal of Environmental Science, 2017
The crop plants are the major source of human nutrition, but insects and pests cause huge economic losses every year. The authors were interested in developing novel insecticidal agents with low toxicity and an acceptable impact on the environment. Thus, 2-amino-5-(substituted)-1, 3, 4-thiadiazoles (1a, b) were used as versatile materials to synthesize
Madkour, H. F, Azab, M. E, Aly, A. F, Khamees, M. S. M   +3 more
openaire   +1 more source

Biological activity of heterocyclic systems based on functionally substituted 1,3,4-thia(oxa)diazoles (a review)

Фармацевтичний журнал, 2019
1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj   +1 more source

2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses

Acta Pharmaceutica, 2020
Parasitic diseases are a serious public health problem affecting hundreds of millions of people worldwide. African trypanosomiasis, American trypanosomiasis, leishmaniasis, malaria and toxoplasmosis are the main parasitic infections caused by protozoan ...
Serban Georgeta
doaj   +1 more source

4-Bromobenzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)

Molbank, 2022
Bromoderivatives of benzofused 1,2,5-thiadiazoles are important precursors for the synthesis of dyes, which are widely used to design effective photovoltaic materials.
Timofey N. Chmovzh, Daria A. Alekhina, Timofey A. Kudryashev, Oleg A. Rakitin   +3 more
doaj   +1 more source

A Systematic Review of In vitro and In vivo Activities of Anti-Toxoplasma Drugs and Compounds (2006–2016) [PDF]

, 2017
The currently available anti-Toxoplasma agents have serious limitations. This systematic review was performed to evaluate drugs and new compounds used for the treatment of toxoplasmosis.
Ahmad Daryani, Ehsan Ahmadpour, Mahbobeh Montazeri, Mehdi Sharif, Saeed Mehrzadi, Shahabeddin Sarvi   +5 more
core   +1 more source

Syntheses of Diheterocyclic Compounds Based on 2-Thioacetohydrazide-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine

Molecules, 2008
The syntheses of some diheterocyclic compounds from 2-thioacetohydrazide- 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (1) are described. Compound 1 can be converted into triazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles.
Guang-Fu Yang, Hai-Yang Tu, Chao-Nan Chen, Qiong Chen, Zu-Ming Liu   +4 more
doaj   +1 more source

Synthesis under Microwave Irradiation of [1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazoles and Other Diazoles Bearing Indole Moieties and Their Antimicrobial Evaluation

Molecules, 2011
Microwave-assisted synthesis of some novel compounds, namely, 3-(2-methyl-1H-indol-3-yl)-6-aryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 5a,b was accomplished via bromination of 2-methyl-3-[4-(arylideneamino)-5-mercapto-4H-[1,2,4]triazol-3-yl]-1H ...
Sobhi M. Gomha, Sayed M. Riyadh
doaj   +1 more source

I2/DMSO-Catalyzed Transformation of N-tosylhydrazones to 1,2,3-thiadiazoles

Frontiers in Chemistry, 2020
An iodine/DMSO catalyzed selective cyclization of N-tosylhydrazones with sulfur without adding external oxidant was developed for the synthesis of 4-aryl-1,2,3-thiadiazoles.
Weiwei Li, Jun Zhang, Jing He, Liang Xu, Luigi Vaccaro, Ping Liu, Yanlong Gu   +6 more
doaj   +1 more source

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, EarlyView.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources