The search for new 4-amino-5-methyl-4H-1,2,4-triasole-3-thion derivatives with diuretic activity
1,2,4-Triazole derivatives have been widely used in medical practice due to their wide spectrum of biological activities and low toxicity, as they have 1,2,4-triazole cycle in their structure.
T. V. Kravchenko
doaj +1 more source
Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
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The large interest in the plan of search biologically of active agents is caused by the heterocyclic system of 1,2,4-triazole, due to high biological activity, and by the low indexes of toxicness, that inherent it to the structural analogues.
Т. М. Kaplaushenko+2 more
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Unraveling the dynamics of protein-protein interactions in the Gcn2 signal transduction pathway : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology and Genetics, Massey University, Albany, New Zealand [PDF]
Content removed from Publications section due to copyright reasons: Cridge, A. G., Viswewaraiah, J., Ramesh, R., & Sattlegger, E. (2014). Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae
Ramesh, Rashmi
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Novel Syntheses of Some 1, 2, 4‐Triazoles as Potent Bacteriocidal Agents [PDF]
A facile syntheses of 4‐aryl‐5‐(isomeric pyridoyl)‐3H‐1, 2, 4‐triazoles as potent bacteriocidal agents are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P.aeruginosa. All compounds carrying 1, 2,
Ram Janam Singh, Dharmendra Kumar Singh
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Synthesis of some novel Schiff bases containing 1,2,4-triazole ring [PDF]
4-Allyl-5-piridine-4-yl-4H-1,2,4-triazole-3-thiol was prepared under facile condition via the formation of 2-isonicotinoyl-N-allylhydrazinecarbothioamide. In addition, ethyl[(4-allyl-5-pyridine-4-yl-4H-1¸2¸4-triazole-3-yl)thio]acetate was synthesized via
Ebrahimi, Sattar+3 more
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Syntheses, Characterization and Biological Activity of Some 1, 2, 4‐Triazole Derivatives [PDF]
Syntheses of a series of 3‐alkyl‐4‐ amino‐5‐ cyanomethyl‐4H‐1, 2, 4‐triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa.
R. J. Singh, D. K. Singh
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Synthesis of [(1,2,3-Triazol-1-yl)methyl]boronic Acids Through Click Chemistry: Easy Access to a Potential Scaffold for Protease Inhibitors [PDF]
Stereoselective synthesis of previously unreported [(1,2,3-triazol-1-yl)methyl]boronic acids has been achieved from azidomethylboronates by copper-catalyzed azide–alkyne cycloaddition reaction.
CASELLI, Emilia+2 more
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Chemical investigation of light induced DNA bipyrimidine damage and repair [PDF]
In all organisms, genetic information is stored in DNA and RNA. Both of these macromolecules are damaged by many exogenous and endogenous events, with UV irradiation being one of the major sources of damage.
Carell, Thomas+2 more
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Cobalt has been applied as liners in current Cu interconnect and even as interconnect conductors in next-generation interconnect. In this work, effects of corrosion inhibitors 1, 2, 4-triazole (TAZ) on Co chemical corrosion, galvanic corrosion between Cu
P. He+5 more
semanticscholar +1 more source