Results 21 to 30 of about 46,668 (286)

Antimicrobial and antifungal activity of new fluorophenyl-containing 1,2,4-triazoles

Фармацевтичний журнал, 2021
The achievements of the world organic chemistry are most clearly represented by scientific publications that prove the promising nature of heterocyclic substances.
O. A. Bihdan
doaj   +1 more source

Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety

Hacettepe University Journal of the Faculty of Pharmacy, 2022
The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman, PRUHLO, Yevhen, DUCHENKO, Maryna, KULAGİNA, Mariia, KUDRİA, Victoriia, VALENTYNA, Vashchuk   +5 more
openaire   +2 more sources

Synthesis of substituted 1, 2, 4-triazole derivatives by Microwave irradiation [PDF]

IOSR Journal of Applied Chemistry, 2013
Various substituted Triazole-Thiol containing different functional group have been synthesized by microwave method. The title product 1-((3H-indol-2-ylamino) methyl)-4-phenyl-4, 5-dihydro-1H-1, 2, 4- triazole-3-thiol is synthesized by using amino benzothiazole.
Ashish Asrondkar, Vrushali Patil, Shantanu Pande   +2 more
openaire   +1 more source

Synthesis and Characterization of Carbazole-Benzothiadiazole-Based Conjugated Polymers for Organic Photovoltaic Cells with Triazole in the Main Chain

International Journal of Photoenergy, 2013
We have synthesized a series of carbazole-benzothiadiazole-triazole based copolymers, poly[(N-9′-heptadecanyl-2,7-carbazole)-co-(5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole))-co-((4-(4-butylphenyl)-3,5-diphenyl-4H-1,2,4]triazole))] (PCz3TBTz) by ...
Eunhee Lim
doaj   +1 more source

Antibacterial and antifungal activity of derivatives 3-(alkylthio)-4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The amount of antibiotics has increased over the past decade. This also resulted in increase of microorganisms’ resistance to this class of drugs. Therefore, the synthesis of new compounds that have exhibited antimicrobial and antifungal activity and low
O. A. Suhak, O. І. Panasenko, Ye. G. Knysh, O. M. Kamyshny   +3 more
doaj   +1 more source

Synthesis of novel 3-(2-bromophenyl)-4-substituted-1H-1,2,4-triazole-5(4H)-thiones derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
A wide range of biological activity of 1,2,4-triazole derivatives (anti-inflammatory, antiviral, antitumor, immunostimulating, etc.) and the availability of sources for their preparation determine the prospects of using compounds of this class to create ...
A. A. Safonov , A. V. Nevmyvaka
doaj   +1 more source

Diuretic activity of 3-(5-bromfuran-2-yl)-4-r-(4h)-1,2,4-triazole-5-thione, their S-derivatives and 2-(5-bromfuran-2-yl)-5-r'-thiazolo[3,2-b][1,2,4]triazole-6(5h)-ones

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of study was to investigate diuretic activity of 1,2,4-triazole derivatives which contain С5 atom 5-bromfuran-2-yl substituent in the 1,2,4-triazole nucleus, and to establish interrelation between chemical structure and diuretic action of 1,2,4 ...
Ye. S. Pruglo, A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh   +3 more
doaj   +1 more source

Antioxidant agents in wartime: prospects for the development of new biologically active compounds based on 1,2,4-triazole derivatives

Український журнал військової медицини
Introduction. This article presents an analysis of the antioxidant activity of 4-amino-5-(2-, 3-, 4-nitrophenyl)-1H-1,2,4-triazole-3-thiones and their synthetic analogues, 5-(4-methoxyphenyl, 3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-thiones and their ...
K. K. Isaycheva, A. G. Kaplaushenko, Yu. G. Sameliuk, O. P. Shmatenko, A. M. Solomennyi   +4 more
doaj   +1 more source

Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
One of the most important tasks of modern pharmaceutical science is the search for new biologically active substances, which have high efficacy and low toxicity.
A. S. Gotsulya
doaj   +1 more source

Syntheses of Some 3,5-Diaryl-4H-1,2,4-triazole Derivatives and their Antifungal Activity

E-Journal of Chemistry, 2009
Syntheses of a series of 3, 5-diaryl-4H-1, 2, 4-triazole derivatives are described. In this present work, 4-amino-3-phenyl-5-p-tolyl-4H-1,2,4-triazole(1) was converted to N,N’-bis[3-phenyl-5-p-tolyl-4H-1,2,4-triazolyl]-1,4-xylenediimine(2) and 3-Phenyl-5-
Ram Janam Singh, Dharmendra Kumar Singh
doaj   +1 more source