Directional Macrocycle Transport, Release, and Recapture Enabled by a Rotaxane Transporter
This study represents a bistable rotaxane that enables the directional shuttling, release, and recapture of a dibenzo‐24‐crown‐8 macrocycle upon addition of suitable chemical stimuli. This two‐step molecular transport and release can be followed by NMR and distinct changes in the molecular fluorescence. Based on rational molecular design, the liberated
Sohom Kundu+3 more
wiley +1 more source
Synthesis and Biological Activities of Some 2‐(Substituted‐phenyl)‐2‐methyl‐4‐ (1,2,4‐triazole‐1‐yl)methane‐1,3‐dioxolane Derivatives. [PDF]
Fang‐Fang Jian+3 more
openalex +1 more source
Core‐Twisted, Cationic Perylene Diimides; Homochiral Dimerization and Chiroptical Anion Sensing
The installation of two 3‐methyl‐1,2,3‐triazolium heterocycles on the aromatic core of a perylene diimide (PDI) generates a twisted and cationic organic dye. As potent hydrogen bond donors, these groups enable the PDI to self‐assemble into discrete and robust homochiral dimers in solution.
Denis Hartmann+3 more
wiley +1 more source
Moving beyond multi-triazole to multi-fungicide resistance: Broader selection of drug resistance in the human fungal pathogen Aspergillus fumigatus. [PDF]
Kanellopoulos SG, Snelders E.
europepmc +1 more source
Synthetic Studies Toward Aryl‐(4‐aryl‐4H‐[1,2,4]triazole‐3‐yl)‐amine from 1,3‐Diarylthiourea as Urea Mimetics. [PDF]
Amarnath Natarajan+5 more
openalex +1 more source
Non‐ionic detergents are key reagents for the characterization of membrane protein drug targets. Suitable detergents are commonly identified by trial and error, which leads to failed preparations and raising costs. Recent findings suggest that not only the chemistry of detergents but also the strategy with which detergents and proteins are brought ...
Katharina Alker+2 more
wiley +1 more source
Cuprous iodide implanted in hot-water-soluble-starch coating of ferrite nanoparticles: efficient catalysts for on-water click synthesis of 1,2,3-triazoles. [PDF]
Rezapour Mousavi SM, Rad-Moghadam K.
europepmc +1 more source
Is Mycobacterial InhA a Suitable Target for Rational Drug Design?
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet+7 more
wiley +1 more source
Development of Transiently Strainable Benzocycloheptenes for Catalyst-Free, Visible-Light-Mediated [3 + 2]-Cycloadditions. [PDF]
Kharbanda S+3 more
europepmc +1 more source