Results 151 to 160 of about 18,771 (284)

Directional Macrocycle Transport, Release, and Recapture Enabled by a Rotaxane Transporter

open access: yesChemistry – A European Journal, EarlyView.
This study represents a bistable rotaxane that enables the directional shuttling, release, and recapture of a dibenzo‐24‐crown‐8 macrocycle upon addition of suitable chemical stimuli. This two‐step molecular transport and release can be followed by NMR and distinct changes in the molecular fluorescence. Based on rational molecular design, the liberated
Sohom Kundu   +3 more
wiley   +1 more source

Core‐Twisted, Cationic Perylene Diimides; Homochiral Dimerization and Chiroptical Anion Sensing

open access: yesChemistry – A European Journal, EarlyView.
The installation of two 3‐methyl‐1,2,3‐triazolium heterocycles on the aromatic core of a perylene diimide (PDI) generates a twisted and cationic organic dye. As potent hydrogen bond donors, these groups enable the PDI to self‐assemble into discrete and robust homochiral dimers in solution.
Denis Hartmann   +3 more
wiley   +1 more source

Synthetic Studies Toward Aryl‐(4‐aryl‐4H‐[1,2,4]triazole‐3‐yl)‐amine from 1,3‐Diarylthiourea as Urea Mimetics. [PDF]

open access: green, 2005
Amarnath Natarajan   +5 more
openalex   +1 more source

Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions

open access: yesChemistry – A European Journal, Accepted Article.
Non‐ionic detergents are key reagents for the characterization of membrane protein drug targets. Suitable detergents are commonly identified by trial and error, which leads to failed preparations and raising costs. Recent findings suggest that not only the chemistry of detergents but also the strategy with which detergents and proteins are brought ...
Katharina Alker   +2 more
wiley   +1 more source

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

open access: yesChemMedChem, EarlyView.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet   +7 more
wiley   +1 more source

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