Results 11 to 20 of about 155,151 (257)

Structural and Biochemical Characterization of BdsA from Bacillus subtilis WU-S2B, a Key Enzyme in the “4S” Desulfurization Pathway [PDF]

Frontiers in Microbiology, 2018
Dibenzothiophene (DBT) and their derivatives, accounting for the major part of the sulfur components in crude oil, make one of the most significant pollution sources.
Tiantian Su, Jing Su, Jing Su, Shiheng Liu, Conggang Zhang, Jing He, Yan Huang, Sujuan Xu, Lichuan Gu   +8 more
doaj   +3 more sources

Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies. [PDF]

Lancet Diabetes Endocrinol
Treating older people with diabetes is challenging due to multiple medical comorbidities that might interfere with patients' ability to perform self-care. Most diabetes guidelines focus on improving glycaemia through addition of medications, but few address strategies to reduce medication burden for older adults-a concept known as deprescribing ...
Munshi M, Kahkoska AR, Neumiller JJ, Alexopoulos AS, Allen NA, Cukierman-Yaffe T, Huang ES, Lee SJ, Lipska KJ, McCarthy LM, Meneilly GS, Pandya N, Pratley RE, Rodriguez-Mañas L, Sinclair AJ, Sy SL, Toschi E, Weinstock RS.   +17 more
europepmc   +3 more sources

A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway

Frontiers in Microbiology, 2023
The recent discovery of the archaeal modified mevalonate pathway revealed that the fundamental units for isoprenoid biosynthesis (isopentenyl diphosphate and dimethylallyl diphosphate) are biosynthesized via a specific intermediate, trans ...
Mutsumi Komeyama, Kohsuke Kanno, Hiroyuki Mino, Yoko Yasuno, Tetsuro Shinada, Tomokazu Ito, Hisashi Hemmi   +6 more
doaj   +3 more sources

Resonance Raman Spectroscopic Study of the Unusual [4Fe-4S]²⁺ Cluster of IspH, the Last Enzyme of the Methylerythritol Phosphate Pathway for Terpenoid Biosynthesis. [PDF]

Chembiochem
IspH is the last enzyme of the methylerythritol phosphate pathway. It catalyzes the reductive dehydroxylation of (E)‐4‐hydroxy‐3‐methyl‐but‐2‐en‐1‐yl diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), which are precursors for the biosynthesis of terpenoids, essential molecules for the survival of all living organisms.
Jobelius H, Chaignon P, Bianchino GI, Wandzig J, Hellwig P, Seemann M, Melin F.   +6 more
europepmc   +3 more sources

The Study of Biodesulfurization Activity in Recombinant E. coli Strain by Cloning the dsz Genes Involve in 4S Pathway [PDF]

Journal of Sciences, Islamic Republic of Iran, 2011
Several research groups have attempted to make recombinant bacteria capable of efficient desulfurization of oil fraction. The main aim of this study was to design a recombinant strain in order to desulfurize dibenzothiophen (DBT) and its components found
Jamshid Raheb
doaj   +2 more sources

SLIT3-mediated intratumoral crosstalk induces neuroblastoma differentiation via a spontaneous regression-like program [PDF]

Journal of Translational Medicine
Background Neuroblastoma, the most common pediatric extracranial solid tumor, has heterogeneous clinical outcomes ranging from malignant progression to spontaneous regression.
Meiling Liu, Dekang Lv, Wenjing Yan, Yi Wu, Shulan Wang, Luoxuan Wang, Jie Lei, Deshun Zeng, Zifeng Wang, Fang Liu, Bing Deng, Quentin Liu, Bin He, Min Yan   +13 more
doaj   +2 more sources

Characteristics of dibenzothiophene desulfurization by Rhodococcus erythropolis R1 and its Dsz-negative mutant [PDF]

Biological Journal of Microorganism, 2014
Introduction: Biodesulfurization is used as a selective method for lowering the sulfur content of petroleum products. Materials and methods: A sulfur-oxidation bacterial strain named Rhodococcus erythropolis R1 (NCBI GenBank Accession No.
Zahra Etemadifar , Simone Cappello, Seyed Hamid Zarkesh-Esfahani   +2 more
doaj   +1 more source

4S‐AF scheme and ABC pathway guided management improves outcomes in atrial fibrillation patients [PDF]

European Journal of Clinical Investigation, 2022
AbstractBackgroundThe 4S‐AF scheme and the ABC pathway for integrated care have been proposed to better characterize and treat patients with atrial fibrillation (AF). We aimed to evaluate the assessment of the 4S‐AF scheme and ABC pathway in Chinese AF patients.MethodsThe ChiOTEAF is a prospective, observational, multicentre registry.
Guo, Yutao, Imberti, Jacopo F, Kotalczyk, Agnieszka, Wang, Yutang, Lip, Gregory Y H   +4 more
openaire   +3 more sources

Enhancing biodesulfurization by engineering a synthetic dibenzothiophene mineralization pathway

Frontiers in Microbiology, 2022
A synthetic dibenzothiophene (DBT) mineralization pathway has been engineered in recombinant cells of Pseudomonas azelaica Aramco J strain for its use in biodesulfurization of thiophenic compounds and crude oil.
Igor Martínez, Magdy El-Said Mohamed, José Luis García, Eduardo Díaz   +3 more
doaj   +1 more source

Biodesulfurizing Microbes in the Petroleum Refinery Areas of Saudi Arabia

Journal of Pure and Applied Microbiology, 2023
Gordonia sp., Rhodococcus, Paenibaccilus, Mycobacterium and many other desulfurizing strains have shown good potential for dibenzothiophene (DBT), 4, 6-Dimethyldibenzothiophene (4-6-Dimethyl dibenzothiophene) and other organosulfur biodesulfurization ...
Abrar Ahmad, Othman A. Baothman, Muhammad Shahid Nadeem, Varish Ahmad   +3 more
doaj   +1 more source