Results 21 to 30 of about 1,259,729 (236)

Biodesulfurization Induces Reprogramming of Sulfur Metabolism in Rhodococcus qingshengii IGTS8: Proteomics and Untargeted Metabolomics

Microbiology Spectrum, 2021
Sulfur metabolism in fuel-biodesulfurizing bacteria and the underlying physiological adaptations are not understood, which has impeded the development of a commercially viable bioprocess for fuel desulfurization.
Aurélie Hirschler, Christine Carapito, Loïc Maurer, Julie Zumsteg, Claire Villette, Dimitri Heintz, Christiane Dahl, Ashraf Al-Nayal, Vartul Sangal, Huda Mahmoud, Alain Van Dorsselaer, Wael Ismail   +11 more
doaj   +1 more source

A conserved motif liganding the [4Fe–4S] cluster in [4Fe–4S] fumarases prevents irreversible inactivation of the enzyme during hydrogen peroxide stress

Redox Biology, 2019
Organisms have evolved two different classes of the ubiquitous enzyme fumarase: the [4Fe–4S] cluster-containing class I enzymes are oxidant-sensitive, whereas the class II enzymes are iron-free and therefore oxidant-resistant.
Zheng Lu, James A. Imlay
doaj   +1 more source

The Radical SAM Heme Synthase AhbD from Methanosarcina barkeri Contains Two Auxiliary [4Fe-4S] Clusters

Biomolecules, 2023
In archaea and sulfate-reducing bacteria, heme is synthesized via the siroheme-dependent pathway. The last step of this route is catalyzed by the Radical SAM enzyme AhbD and consists of the conversion of iron-coproporphyrin III into heme. AhbD belongs to
Isabelle Fix, Lorenz Heidinger, Thorsten Friedrich, Gunhild Layer   +3 more
doaj   +1 more source

Cysteine Methylation Controls Radical Generation in the Cfr Radical AdoMet rRNA Methyltransferase [PDF]

, 2013
The 'radical S-adenosyl-L-methionine (AdoMet)' enzyme Cfr methylates adenosine 2503 of the 23S rRNA in the peptidyltransferase centre (P-site) of the bacterial ribosome.
Driesener, RC, Challand, MR, Christopher W M Kay, Salvadori, E, Peter L Roach, Driesener, Rebecca C., Roach, PL, Salvadori, Enrico, Challand, Martin R., Spencer, James, Roach, Peter L., Spencer, J, Rebecca C Driesener, Kay, CW, James Spencer, Martin R Challand, Enrico Salvadori, Kay, Christopher W. M.   +17 more
core   +2 more sources

Observation of Υ(4S)→η′Υ(1S) [PDF]

, 2018
We report the first observation of the hadronic transition Υ(4S)→η′Υ(1S), using 496 fb−1 data collected at the Υ(4S)resonance with the Belle detector at the KEKB asymmetric-energy e+e− collider.
Kulasiri, Ratnappuli L., et al., E. Guido   +1 more
core   +5 more sources

Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis.

PLoS Biology, 2015
Interhomolog crossovers promote proper chromosome segregation during meiosis and are formed by the regulated repair of programmed double-strand breaks. This regulation requires components of the synaptonemal complex (SC), a proteinaceous structure formed
Xiangyu Chen, Ray T Suhandynata, Rima Sandhu, Beth Rockmill, Neeman Mohibullah, Hengyao Niu, Jason Liang, Hsiao-Chi Lo, Danny E Miller, Huilin Zhou, G Valentin Börner, Nancy M Hollingsworth   +11 more
doaj   +1 more source

Bromination of endo-7-norbornene derivatives revisited: failure of a computational NMR method in elucidating the configuration of an organic structure

Beilstein Journal of Organic Chemistry, 2023
Previously we reported on the bromination of endo-7-bromonorbornene at different temperatures yielding mixtures of addition products. The structural elucidations of the formed compounds were achieved by NMR spectroscopy. Particularly, the γ-gauche effect
Demet Demirci Gültekin, Arif Daştan, Yavuz Taşkesenligil, Cavit Kazaz, Yunus Zorlu, Metin Balci   +5 more
doaj   +1 more source

Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme

Comptes Rendus. Chimie, 2023
Our previous research revealed that (E)-4-amino-3-methylbut-2-en-1-yl diphosphate (AMBPP) is one of the best inhibitors of IspH, a [4Fe–4S]-dependent enzyme involved in the methylerythritol phosphate pathway that is a valuable target for the discovery of
Petit, Benoît Eric, Jobelius, Hannah, Bianchino, Gabriella Ines, Guérin, Mélina, Borel, Franck, Chaignon, Philippe, Seemann, Myriam   +6 more
doaj   +1 more source

Microbial (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase (IspH) and its biotechnological potential: A mini review

Frontiers in Bioengineering and Biotechnology, 2022
(E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate (HMBPP) reductase (IspH) is a [4Fe-4S] cluster-containing enzyme, involved in isoprenoid biosynthesis as the final enzyme of the methylerythritol phosphate (MEP) pathway found in many bacteria and malaria ...
Shiyong Huang, Shiyong Huang, Yanfen Xue, Yanhe Ma, Cheng Zhou   +4 more
doaj   +1 more source

Exploring the potential targets of the Abrus cantoniensis Hance in the treatment of hepatitis E based on network pharmacology

Frontiers in Veterinary Science, 2023
Hepatitis E is a disease of public health significance caused by the cross-species transmission of zoonotic hepatitis E virus (HEV) infection. There are no specific drugs.
Ziheng Xu, Can Wang, Zuxiang Luan, Dapei Zhang, Baiqing Dong   +4 more
doaj   +1 more source