Results 31 to 40 of about 117,075 (151)
Beilstein Journal of Organic Chemistry, 2023 Previously we reported on the bromination of endo-7-bromonorbornene at different temperatures yielding mixtures of addition products. The structural elucidations of the formed compounds were achieved by NMR spectroscopy. Particularly, the γ-gauche effect
Demet Demirci Gültekin +5 more
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Comptes Rendus. Chimie, 2023 Our previous research revealed that (E)-4-amino-3-methylbut-2-en-1-yl diphosphate (AMBPP) is one of the best inhibitors of IspH, a [4Fe–4S]-dependent enzyme involved in the methylerythritol phosphate pathway that is a valuable target for the discovery of
Petit, Benoît Eric +6 more
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Frontiers in Bioengineering and Biotechnology, 2022 (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate (HMBPP) reductase (IspH) is a [4Fe-4S] cluster-containing enzyme, involved in isoprenoid biosynthesis as the final enzyme of the methylerythritol phosphate (MEP) pathway found in many bacteria and malaria ...
Shiyong Huang +4 more
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Frontiers in Veterinary Science, 2023 Hepatitis E is a disease of public health significance caused by the cross-species transmission of zoonotic hepatitis E virus (HEV) infection. There are no specific drugs.
Ziheng Xu +4 more
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Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)‐4‐hydroxy‐3‐methylbut‐2‐enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe–4S] protein [PDF]
FEBS Letters, 2003 The last enzyme (LytB) of the methylerythritol phosphate pathway for isoprenoid biosynthesis catalyzes the reduction of (E)‐4‐hydroxy‐3‐methylbut‐2‐enyl diphosphate into isopentenyl diphosphate and dimethylallyl diphosphate. This enzyme possesses a dioxygen‐sensitive [4Fe–4S] cluster.
Wolff, Murielle +9 more
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Genetic analysis of benzothiophene biodesulfurization pathway of Gordonia terrae strain C-6. [PDF]
PLoS ONE, 2013 Sulfur can be removed from benzothiophene (BT) by some bacteria without breaking carbon-carbon bonds. However, a clear mechanism for BT desulfurization and its genetic components have not been reported in literatures so far.
Wei Wang +6 more
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Ecotoxicology and Environmental SafetyDifenoconazole (DIF) is a typical chiral triazole fungicide extensively detected in the environment. This study aimed to explore the stereoselective cardiovascular toxicity of DIF and its four stereoisomers (2S,4S-, 2S,4R-, 2 R,4R-, and 2 R,4S-DIF) in ...
Jiansheng Zhu +5 more
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Biocatalytic desulfurization of thiophenic compounds and crude oil by newly isolated bacteria
Frontiers in Microbiology, 2015 Microorganisms possess enormous highly specific metabolic activities, which enable them to utilize and transform nearly every known chemical class present in crude oil.
Magdy El-Said Mohamed +2 more
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Exploring the electron transfer pathway in the oxidation of avermectin by CYP107Z13 in Streptomyces ahygroscopicus ZB01. [PDF]
PLoS ONE, 2014 Streptomyces ahygroscopicus ZB01 can effectively oxidize 4″-OH of avermectin to form 4″-oxo-avermectin. CYP107Z13 is responsible for this site-specific oxidation in ZB01.
Mei Li +4 more
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Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins
eLife, 2016 Assembly of mitochondrial iron-sulfur (Fe/S) proteins is a key process of cells, and defects cause many rare diseases. In the first phase of this pathway, ten Fe/S cluster (ISC) assembly components synthesize and insert [2Fe-2S] clusters.
Marta A Uzarska +9 more
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