Results 11 to 20 of about 5,174,697 (237)

Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]

Frontiers in Microbiology
Introduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang, Peng Yang, Peng Yang, Yutian Fan, Yajuan Zhao, Yan Yu, Xinping Yan, Lu Han, Xinqiang Song, An-dong Gong, An-dong Gong, An-dong Gong   +11 more
doaj   +2 more sources

Effect of extending the oral administration period of 5‐aminolevulinic acid on diagnostic accuracy and treatment outcomes for non–muscle‐invasive bladder cancer [PDF]

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives To evaluate the treatment outcomes of 5‐aminolevulinic acid hydrochloride (5‐ALA) photodynamic diagnosis (PDD)‐assisted transurethral resection of bladder tumour (TURBT) (ALA PDD‐TURBT, hereinafter referred to as ‘ALA‐PDD’) exceeding 4 h after ALA administration for non–muscle‐invasive bladder cancer (NMIBC).
Hideo Fukuhara, Ryu Shigehisa, Shinkuro Yamamoto, Satoshi Fukata, Kenta Saito, Yasuhiko Shibanaka, Keiji Inoue   +6 more
wiley   +2 more sources

Advances in 5-Aminolevulinic Acid Priming to Enhance Plant Tolerance to Abiotic Stress

International Journal of Molecular Sciences, 2022
Priming is an adaptive strategy that improves plant defenses against biotic and abiotic stresses. Stimuli from chemicals, abiotic cues, and pathogens can trigger the establishment of priming state.
Shuya Tan, Jie Cao, X. Xia, Zhonghai Li
semanticscholar   +1 more source

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +1 more source

Clinical guidelines and expediency of using 5-aminolevulinic acid for intraoperative visualization of margins of malignant tumors of the oral cavity

Опухоли головы и шеи, 2022
Introduction. Treatment of the oral cavity is an important problem of current oncology due to high morbidity and mortality reaching 43 % in 5-year period after diagnosis.
Yu. V. Alymov, A. V. Ignatova, I. S. Romanov   +2 more
doaj   +1 more source

Turning on the light for brain tumor surgery: A 5-aminolevulinic acid story

Neuro-Oncology, 2022
To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies have been developed to improve visualization of target tissue.
D. McCracken, A. Schupper, N. Lakomkin, J. Malcolm, David Painton Bray, C. Hadjipanayis   +5 more
semanticscholar   +1 more source

MeJA-mediated enhancement of salt-tolerance of Populus wutunensis by 5-aminolevulinic acid

BMC Plant Biology, 2023
Background 5-Aminolevulinic acid (ALA) is a natural and environmentally benign multifunctional plant growth regulator involved in the regulation of plant tolerance to various environmental stresses. This research aimed to explore the molecular mechanisms
Huan Liu, Jingliang Sun, Jixiang Zou, Baisheng Li, Huanxiao Jin   +4 more
semanticscholar   +1 more source

Effect of 5-Aminolevulinic Acid and Sodium Fluorescein on the Extent of Resection in High-Grade Gliomas and Brain Metastasis

Cancers, 2022
Simple Summary Complete surgical removal of high-grade gliomas (HGG) is known to increase the overall survival and progression-free survival. Several studies have shown that fluorescence-guided surgery with 5-aminolevulinic acid (5-ALA) increases gross ...
Lasse Cramer Ahrens, Mathias Green Krabbenhøft, R. W. Hansen, N. Mikic, C. B. Pedersen, F. Poulsen, A. Korshoej   +6 more
semanticscholar   +1 more source

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

Gels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini   +8 more
doaj   +1 more source

Molecular and Metabolic Mechanisms Underlying Selective 5-Aminolevulinic Acid-Induced Fluorescence in Gliomas

Cancers, 2021
Simple Summary 5-aminolevulinic acid (5-ALA) is a medication that produces fluorescence in certain cancers, which enables surgeons to visualize tumor margins during surgery.
Jeffrey I. Traylor, M. Pernik, Alex C Sternisha, S. McBrayer, K. Abdullah   +4 more
semanticscholar   +1 more source