Results 61 to 70 of about 134,788,912 (103)

Ne-22 Ion-Beam Radiation Damage to DNA: From Initial Free Radical Formation to Resulting DNA-Base Damage. [PDF]

ACS Omega, 2021
Kant M, Jaruga P, Coskun E, Ward S, Stark AD, Baumann T, Becker D, Adhikary A, Sevilla MD, Dizdaroglu M.   +9 more
europepmc   +1 more source

Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.

, 2001
The effects of 2-chloro-2'-deoxyadenosine (CdA, cladribine), an adenosine deaminase-resistant analogue toxic for both proliferating and resting lymphoid cells, were investigated in the human leukemia cell line EHEB, which was derived from a patient with ...
Delacauw, Anne, Rosier, Jean-François, Bontemps, Françoise, Ferrant, Augustin, Smal, Caroline, Cardoen, Sabine, Van den Berghe, Georges, Van Den Neste, Eric   +7 more
core  

Understanding APE1 cellular functions by the structural preference of exonuclease activities. [PDF]

Comput Struct Biotechnol J, 2021
Liu TC, Guo KW, Chu JW, Hsiao YY.
europepmc   +1 more source

Biochemical Pharmacology and Resistance to 2-Chloro-2′-arabino-fluoro-2′-deoxyadenosine, a Novel Analogue of Cladribine in Human Leukemic Cells

, 1999
The objective of the present study was to investigate the biochemical pharmacology of 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine (CAFdA) — a fluorinated analogue of cladribine [2-chloro-2′-deoxyadenosine, Leustatin (CdA)] with improved acid and ...
Peterson, Curt,, Spasokoukotskaja, Tatjana,, Pettersson, Birgitta,, Liliemark, Jan,, Lotfi, Kourosh,, Eriksson, Staffan,   +5 more
core  

For the Better or for the Worse? The Effect of Manganese on the Activity of Eukaryotic DNA Polymerases. [PDF]

Int J Mol Sci, 2023
Balint E, Unk I.
europepmc   +1 more source

Triple helix binding of oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine

Formation of a triple helix between an oligodeoxyribonucleotide contg. 8-oxo-2'-deoxyadenosine and a DNA duplex target was studied as a function of pH. Above pH 7.4, the triple helix with the 8-oxo-2'-deoxyadenosine was more stable than the complex with ...
Johnsson, Kai, Davison, Edwin C.
core   +1 more source

DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates. [PDF]

Biomolecules
Sarsenbayeva U, Gasparutto D, Geacintov N, Ishchenko AA, Zhamanbayeva G, Sharipov KO, Trasviña-Arenas CH, David SS, Zharkov DO, Matkarimov BT, Saparbaev M, Taipakova S.   +11 more
europepmc   +1 more source

Biomimetic Studies on the Reactivity of Sulfur-Centered Radicals with Purine Moieties of DNA. [PDF]

Biomolecules
Masi A, Barata-Vallejo S, Chatgilialoglu C.   +2 more
europepmc   +1 more source

Diastereomeric 5',8-cyclo-2'-deoxypurines: brief overview of synthetic strategies, modelling and in vitro biological activity

, 2015
Diastereomeric 5',8-cyclo-2'-deoxypurines: brief overview of synthetic strategies, modelling and in vitro biological activity. 5?,8-cyclo-2?-deoxypurines (cdPus) are typical DNA lesions resulting from endogenous and environmental free radical stress. The
Chryssostomos Chatgilialoglu, Annalisa Masi   +1 more
core  

Investigation of Oxidative DNA Damage Levels in Urine of Healthcare Workers Exposed to Ionizing Radiation. [PDF]

Toxics
Yurt A, Beyan AC, Tuna G, Manisalıgil YA, Özcan S, Oğuzhan H.   +5 more
europepmc   +1 more source