Results 51 to 60 of about 35,270,628 (98)

Bypass of a 5',8-cyclo-2'-deoxynucleoside by DNA polymerase beta leads to trinucleotide repeat deletion.

open access: yes, 2014
5',8-cyclo-2'-deoxynucleosides such as a 5',8-cyclo-dA or 5',8-cyclo-dG are common forms of oxidized DNA base lesions that are usually induced by hydroxyl radicals produced via endogenous and environmental oxidative stress as well as ionizing radiation.
M Xu   +5 more
core  

DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates. [PDF]

open access: yesBiomolecules
Sarsenbayeva U   +11 more
europepmc   +1 more source

Diastereomeric 5',8-cyclo-2'-deoxypurines: brief overview of synthetic strategies, modelling and in vitro biological activity

open access: yes, 2015
Diastereomeric 5',8-cyclo-2'-deoxypurines: brief overview of synthetic strategies, modelling and in vitro biological activity. 5?,8-cyclo-2?-deoxypurines (cdPus) are typical DNA lesions resulting from endogenous and environmental free radical stress. The
Chryssostomos Chatgilialoglu   +1 more
core  

Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.

open access: yes, 2001
The effects of 2-chloro-2'-deoxyadenosine (CdA, cladribine), an adenosine deaminase-resistant analogue toxic for both proliferating and resting lymphoid cells, were investigated in the human leukemia cell line EHEB, which was derived from a patient with ...
Delacauw, Anne   +7 more
core  

Aflatoxin B<sub>1</sub>-induced DNA adduct formation in murine kidney and liver. [PDF]

open access: yesEnviron Toxicol Pharmacol
Jaruga P   +4 more
europepmc   +1 more source

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