5',8-cyclo-2'-deoxynucleosides such as a 5',8-cyclo-dA or 5',8-cyclo-dG are common forms of oxidized DNA base lesions that are usually induced by hydroxyl radicals produced via endogenous and environmental oxidative stress as well as ionizing radiation.
M Xu +5 more
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DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates. [PDF]
Sarsenbayeva U +11 more
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Diastereomeric 5',8-cyclo-2'-deoxypurines: brief overview of synthetic strategies, modelling and in vitro biological activity. 5?,8-cyclo-2?-deoxypurines (cdPus) are typical DNA lesions resulting from endogenous and environmental free radical stress. The
Chryssostomos Chatgilialoglu +1 more
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Biomimetic Studies on the Reactivity of Sulfur-Centered Radicals with Purine Moieties of DNA. [PDF]
Masi A +2 more
europepmc +1 more source
Investigation of Oxidative DNA Damage Levels in Urine of Healthcare Workers Exposed to Ionizing Radiation. [PDF]
Yurt A +5 more
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Pioneering contribution of Professor Bruce Ames to early development in biochemical aspects of oxidatively generated damage to DNA. [PDF]
Cadet J, Wagner JR.
europepmc +1 more source
Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
The effects of 2-chloro-2'-deoxyadenosine (CdA, cladribine), an adenosine deaminase-resistant analogue toxic for both proliferating and resting lymphoid cells, were investigated in the human leukemia cell line EHEB, which was derived from a patient with ...
Delacauw, Anne +7 more
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Production, Isolation, and Characterization of Stable Isotope-Labeled Standards for Mass Spectrometric Measurements of Oxidatively-Damaged Nucleosides in RNA. [PDF]
Jaruga P, Kant M, Dizdaroglu M.
europepmc +1 more source
Protocol for the simultaneous quantification of oxidative purine lesions in DNA using LC-MS/MS analysis. [PDF]
Chatgilialoglu C +2 more
europepmc +1 more source
Aflatoxin B<sub>1</sub>-induced DNA adduct formation in murine kidney and liver. [PDF]
Jaruga P +4 more
europepmc +1 more source

