Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner. [PDF]
Toxics, 2019 As described elsewhere in this Special Issue on biomarkers, much progress has been made in the detection of modified DNA within organisms at endogenous and exogenous levels of exposure to chemical species, including putative carcinogens and ...
Bian K, Delaney JC, Zhou X, Li D.
europepmc +3 more sources
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
Biomimetic Radical Chemistry and Applications 2021 [PDF]
, 2022 The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level.
core +1 more source
Biomimetic Radical Chemistry and Applications [PDF]
, 2020 The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level.
Chatgilialoglu, Chryssostomos
core +1 more source
DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies [PDF]
, 2022 Computational fluid dynamics (CFD), which uses numerical analysis to predict and model complex flow behaviors and transport processes, has become a mainstream tool in engineering process research and development.
core +1 more source
Epigenetic Instability Induced by DNA Base Lesion via DNA Base Excision Repair [PDF]
, 2017 DNA damage can cause genome instability, which may lead to human cancer. The most common form of DNA damage is DNA base damage, which is efficiently repaired by DNA base excision repair (BER).
Zhongliang Jiang
semanticscholar +3 more sources
Radiobiology Textbook:Space Radiobiology [PDF]
, 2023 The study of the biologic effects of space radiation is considered a “hot topic,” with increased interest in the past years. In this chapter, the unique characteristics of the space radiation environment will be covered, from their history ...
Arena, Carmen +24 more
core +4 more sources
Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound [PDF]
, 2006 Fish living in contaminated environments accumulate toxic chemicals in their tissues. Biomarkers are needed to identify the resulting health effects, particularly focusing on early changes at a subcellular level.
Beer +98 more
core +5 more sources
Oxidative DNA damage modulates genome and epigenome integrity via base excision repair [PDF]
, 2021 Oxidative DNA damage is one of the leading causes of genome instability, cell death, and diseases. It is repaired by DNA base excision repair (BER), during which repair and translesion DNA polymerases may incorporate damaged nucleotides and mediate RNA ...
Tsegay, Pawlos S.
core +1 more source
A 5\u27, 8-cyclo-2\u27-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β. [PDF]
, 2014 5′,8-cyclo-2′-deoxypurines (cdPus) are common forms of oxidized DNA lesions resulting from endogenous and environmental oxidative stress such as ionizing radiation.
Chatgilialoglu, Chryssostomos +6 more
core +2 more sources