Results 211 to 220 of about 345,197 (240)

Transcriptional and epigenetic changes associated with lead exposure in spermatozoa. [PDF]

Asian J Androl
Zhang X, Shen XR, Wu B, Wang XM, Shi HJ, Zhang TC.   +5 more
europepmc   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, Volume 13, Issue 37, 3 July 2026.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Genome-wide ribosome profiling reveals a dynamic translational landscape in Arabidopsis seedling roots under simulated microgravity. [PDF]

Commun Biol
Zhang T, Zhang L, Yang Y, Hu J, Zheng H, Cai W, Xu P.   +6 more
europepmc   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, Volume 100, Issue 1, Page 48-58, July 2026.
[Color figure can be viewed at www.annalsofneurology.org] Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1 ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Beyond the vaccine baseline: Optimizing mRNA stability and translation via regulatory element engineering. [PDF]

Mol Ther Nucleic Acids
Cagnin S.
europepmc   +1 more source

Exploring Genetic Contributions to Prostate Cancer Risk in an Asian Population‐Based Study

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Genetic susceptibility to prostate cancer (PCa) varies across populations, yet East Asian men remain underrepresented in genome‐wide association studies (GWAS). This study aimed to identify genetic variants associated with PCa in a Taiwanese cohort and to explore their potential biological relevance using integrative annotation ...
Jiun‐Hung Geng, Chia‐Cheng Yu, Chao‐Yuan Huang, Victor C. Lin, Chia‐Yang Li, Ming‐Tsang Wu, Szu‐Chia Chen, Bo‐Ying Bao, Shu‐Pin Huang   +8 more
wiley   +1 more source

CRISPR-Cas9-mediated targeted gene deletion in <i>Aspergillus calidoustus</i>, a non-model environmental mold. [PDF]

Microbiol Spectr
Hollomon JM, Dahlstrom KM.
europepmc   +1 more source

Identification of Wheat Sulfotransferase Genes and Functional Analysis of TaSOT48 Regulatory Responses to Biotic and Abiotic Stress Conditions

Food and Energy Security, Volume 15, Issue 4, July/August 2026.
ABSTRACT Sulfotransferases (SOTs) catalyze sulfate conjugation and contribute to diverse biochemical processes in plants. In this study, 112 wheat SOT genes were identified and characterized through genome‐wide analyses. The TaSOT genes were unevenly distributed across 21 chromosomes, and duplication analysis revealed 35 duplicated gene pairs that have
Daniel Bimpong, Youning Wang, Ye Dong, Tian Yang, Wenqi Shi, Peter Mensah, Mawuli Korsi Amenyogbe, Dongfang Ma, Zhengwu Fang   +8 more
wiley   +1 more source

Development of an HRM-qRT-PCR platform for fast and cost-effective genotyping of infectious bronchitis virus in Egypt. [PDF]

Sci Rep
Ali A, Prince A, Aljuaydi SH, Yassin AM, Khalifa R, Dardir S, Moussa SZ.   +6 more
europepmc   +1 more source

The specific features of the thyroid hormone receptor gene <i>THRB</i> polymorphism in indigenous populations of Siberia. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Malyarchuk BA, Pokhilyuk NV, Denisova GA, Litvinov AN.   +3 more
europepmc   +1 more source