RNA variation as the driver of genomic efficiency and phenotypic complexity. [PDF]
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High prevalence of seronegative occult hepatitis C in high-risk individuals. [PDF]
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Overflow urinary incontinence as an early manifestation of neuronal intranuclear inclusion disease (NIID): a case report. [PDF]
Yang M, Wu Z, Ju G, Duan T.
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Characterization and evolution of 5′ and 3′ untranslated regions in eukaryotes
Untranslated regions (UTRs) in eukaryotes play a significant role in the regulation of translation and mRNA half-life, as well as interacting with specific RNA-binding proteins.
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The gene for CspA, the major cold-shock protein in Escherichia coli, is tightly regulated at both optimal and low temperatures. While CspA is drastically induced after temperature downshift, it is hardly detectable at 37 degrees C. Here we demonstrate that the deletion of parts of the 5'-untranslated region (5'-UTR) of the cspA mRNA results in ...
L, Fang, B, Xia, M, Inouye
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Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements [PDF]
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes.
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Structural and functional features of eukaryotic mRNA untranslated regions
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