Use of 5-alpha-reductase inhibitors did not increase the risk of cardiovascular diseases in patients with benign prostate hyperplasia: a five-year follow-up study. [PDF]
PLoS ONE, 2015 This nationwide population-based study investigated the risk of cardiovascular diseases after 5-alpha-reductase inhibitor therapy for benign prostate hyperplasia (BPH) using the National Health Insurance Research Database (NHIRD) in Taiwan.In total, 1 ...
Teng-Fu Hsieh +8 more
doaj +2 more sources
Prostate Cancer Mortality and Use of 5-Alpha Reductase Inhibitors [PDF]
The World Journal of Men's Health, 2020 Cara A. Foldes +2 more
doaj +5 more sources
Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome [PDF]
Skin Appendage Disorders, 2016 Postfinasteride syndrome (PFS) is a term recently coined to characterize a constellation of reported undesirable side effects described in postmarketing reports and small uncontrolled studies that developed during or after stopping finasteride treatment, and persisted after drug discontinuation. Symptoms included decreased libido, erectile dysfunction,
Raymond Fertig +3 more
openaire +3 more sources
Management of patients with lower urinary tract symptoms due to benign prostatic enlargement at risk of progression treated with 5-alpha-reductase inhibitors: examining real-world clinical practice in Spain and Brazil [PDF]
BMC UrologyBackground For patients with lower urinary tract symptoms due to benign prostatic enlargement (LUTS/BPE), assessing patient risk of disease progression is important to determine if treatment with 5-alpha-reductase inhibitors (5ARIs) is warranted ...
Juan Manuel Palacios +7 more
doaj +2 more sources
Antipsychotic-Like Properties of 5-α-Reductase Inhibitors [PDF]
Neuropsychopharmacology, 2008 Recent evidence indicates that neuroactive steroids may participate in the pathogenesis of schizophrenia spectrum disorders, yet the mechanisms of this involvement are elusive. As 5-alpha-reductase (5AR) is the rate-limiting enzyme of one of the two major metabolic pathways in brain steroidogenesis, we investigated the effects of its blockade in ...
Bortolato M +7 more
openaire +6 more sources
The Long-Term Impact of 5-alpha Reductase Inhibitors on the Development of Bladder Cancer and the Need for Radical Cystectomy: A Nationwide Observational Study [PDF]
The World Journal of Men's HealthPurpose: To investigate the long-term effects of taking 5-alpha reductase inhibitors (5ARIs) on the development of bladder cancer (BC) and the implementation of radical cystectomy (RC), a standard procedure for advanced BC.
Jong Hyun Pyun +5 more
doaj +2 more sources
5-alpha Reductase inhibitors and risk of male breast cancer: a systematic review and meta-analysis [PDF]
International Brazilian Journal of Urology, 2018 Objective: To assess the relationship between 5α-reductase inhibitors (5ARIs) and the risk of male breast cancer (MBC). Material and Methods: We systematically searched Medline via PubMed, Embase and the Cochrane Library Central Register up to May 2017 ...
Jiamin Wang +5 more
doaj +2 more sources
May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications? [PDF]
Med Hypotheses, 2020 COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females.
Adamowicz J, Juszczak K, Drewa T.
europepmc +2 more sources
High Real-World Medication Adherence and Durable Clinical Benefit in Medicare Patients Treated with 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia [PDF]
Journal of Urology, 2020 Aria F. Olumi +2 more
exaly +2 more sources
Post-finasteride syndrome, [PDF]
Anais Brasileiros de Dermatologia, 2020 Finasteride is a 5α-reductase enzyme inhibitor that has been approved for the treatment of male androgenic alopecia since 1997. Over time, it has been considered a safe and well-tolerated drug with rare and reversible side effects.
Ana Francisca Junqueira Ribeiro Pereira +1 more
doaj +1 more source