Results 31 to 40 of about 44,133 (142)
Bothersome Hematospermia Following Stereotactic Body Radiation Therapy for Prostate Cancer
Frontiers in Oncology, 2021 BackgroundHematospermia following prostate radiation therapy is a benign and often self-limiting side effect. However, it may be bothersome to some men and their partners with a negative impact on sexual quality of life (QOL).
Sarthak Shah +7 more
doaj +1 more source
5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection
The Journal of Sexual Medicine, 2008 ABSTRACT Introduction Benign prostatic hyperplasia (BPH) is a common problem affecting middle-aged and elderly men. First-line medical therapy includes α 1blockers and 5α-reductase inhibitors (5ARIs), such as finasteride and dutasteride.
Fikret, Erdemir +2 more
openaire +2 more sources
Inhibition of sterol biosynthesis in animal cells by 14 alpha-hydroxymethyl sterols.
Journal of Lipid Research, 1980 The chemical syntheses of a number of 14 alpha-hydroxymethyl sterols and 14 alpha -hydroxymethyl-15 alpha-hydroxysterols and their derivatives have been pursued to permit evaluation of their activity in the inhibition of sterol biosynthesis in animal ...
G J Schroepfer, Jr +3 more
doaj +1 more source
Revista Médica Clínica Las Condes, 2023 Resumen: Introducción: La alopecia frontal fibrosante (AFF) es una alopecia linfocítica primaria cicatricial, cuya patogenia se desconoce. Se han desarrollado distintos regímenes de tratamientos farmacológicos, siendo el finasteride por sí sólo o en ...
Néstor Carreño-Orellana +3 more
doaj +1 more source
Effects of 5-alpha reductase inhibitors
Current Opinion in Urology, 2018 The use of 5-alpha reductase inhibitors (5ARIs) for the treatment of benign prostatic hyperplasia (BPH) and other diseases has been proposed and studied. However, the controversy about its benefits and harms for other diseases has persisted. In this review, we will discuss the newly identified effects of 5ARIs based on recently published studies.These ...
Joo Yong, Lee, Kang Su, Cho
openaire +3 more sources
International Brazilian Journal of Urology, 2013 Objectives Five-alpha reductase inhibitors (5ARIs) are known as chemopreventive agents in prostate cancer with a risk of high-grade disease. This study evaluated the effects of 5ARI on androgen receptor (AR) and proteins involved in prostate cell growth ...
Chaeyong Jung +4 more
doaj +1 more source
Evaluation of apoptosis indexes in currently used oral alpha-blockers in prostate: a pilot study
International Brazilian Journal of UrologyObjectives: Apoptosis effect of oral alpha-blockers is known in the prostate. Apoptosis index of silodosin has not been proved, yet. Aims are to present apoptosis index of silodosin in prostate and to compare this with other currently used alpha-blocker ...
Mehmet Demir +6 more
doaj +1 more source
Diagnostics, 2021 Bladder cancer (BCa) is an endocrine-related tumour and the activation of androgen signalling pathways may promote bladder tumorigenesis. We summarized the available preclinical and clinical evidence on the implications of the manipulation of androgen ...
Massimiliano Creta +14 more
doaj +1 more source
The use of 5-alpha-reductase inhibitors for the prevention of prostate cancer [PDF]
Cancer Biology & Therapy, 2010 The use of 5-alpha-reductase inhibitors has been studied not only in benign prostatic hyperplasia, but as a chemopreventive strategy in prostate cancer. Both finasteride and dutasteride, 5 alpha-reductase inhibitors (5ARI), have been shown to decrease the risk of prostate cancer.
Eun-mi, Yu +2 more
openaire +2 more sources
Risk of Depression after 5 Alpha Reductase Inhibitor Medication: Meta-Analysis
The World Journal of Men's Health, 2020 Purpose: Although five-alpha reductase inhibitor (5-ARI) is one of standard treatment for benign prostatic hyperplasia (BPH) or alopecia, potential complications after 5-ARI have been issues recently.
Jae Heon Kim +5 more
doaj +1 more source