Results 211 to 220 of about 42,924 (245)
Some of the next articles are maybe not open access.
[5-alpha-reductase inhibitors in benign prostatic hyperplasia].
Khirurgiia, 1997Sixteen patients presenting benign prostate gland hyperplasia undergo conservative treatment with Finasterid over the period 1992 through 1995. Prior to treatment, in all patients the subjective complaints are assayed on the basis of the IPSS rating system for severity of complaints.
P, Panchev, K, Neĭkov
openaire +1 more source
5 alpha-reductase inhibitors and prostatic disease.
Clinical endocrinology, 19945 alpha-Reductase inhibitors are a new class of substances with very specific effects on type I and type II 5 alpha R which may be of use in the treatment of skin disease, such as male pattern baldness, male acne and hirsutism, as well as prostatic hyperplasia and prostate cancer.
openaire +1 more source
[5-alpha reductase inhibitors and prostate cancer prevention].
Zhonghua nan ke xue = National journal of andrology, 20135-alpha reductase inhibitors decrease the level of dihydrotestosterone (DHT) by inhibiting 5-alpha reductase. Trials on 5-alpha reductase inhibitors in prostate cancer prevention showed that they could significantly decrease the incidence of prostate cancer, but meanwhile increase high-grade cases as well.
openaire +1 more source
Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor.
Pharmacotherapy, 1995Finasteride is a 4-azasteroid inhibitor of one isoenzyme of 5 alpha-reductases that converts testosterone to dihydrotestosterone (DHT). We characterized the time course of DHT concentrations. The following model was used to assess DHT pharmacodynamics: [formula: see text] where joint fitting of three dose levels yielded kin0 = 28% change/hour, kout = 0.
H C, Ko, W J, Jusko
openaire +1 more source
Treatment of hirsutism with 5 alpha-reductase inhibitors.
Clinics in endocrinology and metabolism, 1986Much os the evidence gathered from studies of 5 alpha-reductase activity levels and androgen metabolism in the skin of hirsute women and the excretion of androgen metabolites by hirsute women indicates that 5 alpha-reduced androgens are probably of primary importance in hirsutism.
openaire +1 more source
5-alpha reductase inhibitors and PSA screening for prostate cancer
Pathology, 2014Paul R, McKenzie +3 more
openaire +4 more sources