The time-dependent accumulation of protoporphyrin IX fluorescence in nodular basal cell carcinoma following application of methyl aminolevulinate with an oxygen pressure injection device [PDF]
Clinical TrialJournal ArticleAuthor's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseTopical protoporphyrin (PpIX)-induced photodynamic therapy (PDT) relies on the penetration of the prodrug into the skin ...
Allen, James +5 more
core +1 more source
Acute Intermittent Porphyria: Pathophysiology and Treatment [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90337/1/j.1875-9114.1984.tb03340.x ...
Anderson +76 more
core +1 more source
5-Aminolevulinic acid-based fluorescence diagnostics of cervical preinvasive changes
The purpose of this article is to review the diagnostic possibilities of 5-aminolevulinic acid (5-ALA)-based fluorescence diagnosis of preinvasive cervical changes.
Rasa Vansevičiūtė +2 more
doaj +1 more source
Evaluation of a commercially available rapid urinary porphobilinogen test [PDF]
Background: Demonstration of substantially increased urinary excretion of porphobilinogen is the cornerstone of diagnosing acute porphyria crisis. Because porphobilinogen testing is not implemented on clinical chemistry analysers, respective analyses are
Buttery JE +4 more
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Photodynamic therapy of cutaneous squamous cell carcinoma
Photodynamic therapy has traditionally been used and approved in many countries for the treatment of intraepithelial forms of cutaneous squamous cell carcinoma and precancer – actinic keratosis and Bowen’s disease.
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines [PDF]
BACKGROUND: Acute Intermittent Porphyria is a genetic disorder of heme metabolism, characterized by increased levels of porphyrin precursors, delta-aminolevulinic acid (ALA) and porphobilinogen (PBG).
Adriana De Siervi +31 more
core +4 more sources
Topical 5-aminolevulinic acid photodynamic therapy for genital vitiligo
Vitiligo is an acquired chronic depigmentary skin disorder which results from the destruction of melanocytes. The clinical characteristic of vitiligo is the development of white macules due to the loss of functioning melanocytes in the skin or hair ...
Tingting Gao +6 more
doaj +1 more source
Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R +6 more
core +1 more source
Effect of Oil-in-Water Emulsions on 5-Aminolevulinic Acid Uptake and Metabolism to PpIX in Cultured MCF-7 Cells [PDF]
No Heading: Purpose.: To identify the optimal vehicle for fast and efficient cellular production of the photosensitizer, protoporphyrin IX (PpIX), upon administration of 5-aminolevulinic acid (ALA).
Aemisegger, Caroline +4 more
core
Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification [PDF]
Author's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseBACKGROUND: Dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) is utilized to successfully treat dermatological conditions. This study
Campbell, Sandra M. +2 more
core +1 more source

