Results 11 to 20 of about 14,205,288 (205)

The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2018
5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
doaj   +4 more sources

The Role of 5-Aminolevulinic Acid (5-ALA) and Sleep [PDF]

International Journal of Clinical Medicine, 2013
Objective: To determine if there is a relationship between the administration of the dietary supplement containing 5-Aminolevulinic Acid (5-ALA) and sleep. Methods: A double-blind, randomized parallel-group study was conducted. It was a 4-month study of 40 participants between the ages of 40 and 70. Males and females were recruited equally.
Michael H. Perez, Terry T. Shintani, Beatriz L. Rodriguez, James Davis, Rosanne C. Harrigan   +4 more
core   +4 more sources

In vitro evaluation of cytotoxic properties of 5-Aminolevulinic acid (5-ALA) on bladder cancer cells [PDF]

Photodiagnosis and Photodynamic Therapy, 2020
5-Aminolevulinic (5-ALA) may be used as a photo diagnostic agent in bladder cancer. The aim of this study was to investigate the cytotoxic effect of 5-ALA on bladder cancer cells.T24 cells treated with various concentrations of mitomycin (MC), 5-ALA and an MC/5-ALA mixture were evaluated to determine the role of 5-ALA on MC cytotoxicity.
Usama A, Fahmy, Omar, Fahmy
openaire   +4 more sources

miR-145 mediates the anti-cancer stemness effect of photodynamic therapy with 5-aminolevulinic acid (ALA) in oral cancer cells

Journal of the Formosan Medical Association, 2018
5-Aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) has been used in the treatment of various precancerous and malignant lesions. Our previous work has demonstrated that ALA-PDT possesses the potential to serve as an adjuvant therapy against ...
Chih-Yuan Fang, Pei-Yin Chen, Dennis Chun-Yu Ho, Lo-Lin Tsai, Pei-Ling Hsieh, Ming-Yi Lu, Cheng-Chia Yu, Chuan-Hang Yu   +7 more
doaj   +2 more sources

P18.53.A USING THE PATTERN OF 5-AMINOLEVULINIC ACID (5-ALA) POSITIVE RESIDUE TO PREDICT THE OUTCOME OF GLIOBLASTOMA PATIENTS [PDF]

Neuro Oncol
Abstract BACKGROUND Glioblastoma multiforme (GBM) portends poor prognosis despite multiple attempts at finding newer therapies. The current standard of care remains maximal safe resection. 5-ALA guidance helps to maximise the resection extent but complete removal is not always possible. It is unclear,
Manik, V, Sim, V, MacDonald, M, Mannava, A, Soumpasis, C, Kalaitzoglou, D, Ashkan, K, Bhangoo, R, Gullan, R, Brazil, L, Al-Salihi, O, Vergani, F, Chia, K, Swampillai*, A, Lavrador*, J P   +14 more
europepmc   +3 more sources

Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model

International Journal of Nanomedicine, 2015
Xiaojie Wang,1,2,* Lei Shi,2,* Qingfeng Tu,2 Hongwei Wang,3 Haiyan Zhang,2 Peiru Wang,2 Linglin Zhang,2 Zheng Huang,4 Feng Zhao,5 Hansen Luan,5 Xiuli Wang2 1Shanghai Skin Diseases Clinical College of Anhui Medical University, 2Shanghai Skin Disease ...
Wang X, Shi L, Tu Q, Wang H, Zhang H, Wang P, Zhang L, Huang Z, Zhao F, Luan H, Wang X   +10 more
doaj   +1 more source

Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT)

Scientific Reports
Photodynamic therapy (PDT) is a minimally invasive treatment approved for many types of cancers. PDT involves the administration of photoactive substances called photosensitizers (PS) that selectively accumulate in cancer cells and are subsequently ...
Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa   +3 more
doaj   +3 more sources

In vitro evaluation of 5-aminolevulinic acid (ALA) loaded PLGA nanoparticles

International Journal of Nanomedicine, 2013
Lei Shi,1 Xiuli Wang,1 Feng Zhao,2 Hansen Luan,2 Qingfeng Tu,1 Zheng Huang,3 Hao Wang,2 Hongwei Wang1,41Shanghai Skin Disease Hospital, Shanghai, People's Republic of China; 2National Pharmaceutical Engineering Research Center, China State Institute ...
Shi L, Wang XL, Zhao F, Luan HS, Tu QF, Huang Z, Wang H, Wang HW   +7 more
doaj   +1 more source

5-aminolevulinic acid-incorporated poly(vinyl alcohol) nanofiber-coated metal stent for application in photodynamic therapy

International Journal of Nanomedicine, 2012
Jin Ju Yoo*, Chan Kim*, Chung-Wook Chung, Young-Il Jeong, Dae Hwan KangNational Research and Development Center for Hepatibiliary Disease, Pusan National University Yangsan Hospital, Gyeongnam 626-770, Korea *These authors contributed equally to this ...
Kang DH, Jeong YI, Chung CW, Kim C, Yoo JJ   +4 more
doaj   +1 more source

The Potential of 5-aminolevulinic Acid as a Contrast Agent in MR Imaging: Challenges and Opportunities [PDF]

Journal of Sciences, Islamic Republic of Iran, 2021
Nowadays, 5-aminolevulinic acid (5-ALA) plays an influential role in the detection of malignant tumors as a photodynamic diagnosis tool. Nevertheless, an outlook regarding 5-ALA applicability in magnetic resonance imaging (MRI) has recently emerged. Many
anita Ebrahimpour, Nader Riahi Alam, Mehdi Khoobi   +2 more
doaj   +1 more source