Results 21 to 30 of about 14,205,288 (205)

Evolutionary Trend Analysis of Research on 5-ALA Delivery and Theranostic Applications Based on a Scientometrics Study

Pharmaceutics, 2022
5-aminolevulinic acid (5-ALA) has been extensively studied for its sustainability and broad-spectrum applications in medical research and theranostics, as well as other areas.
You Zhou, Mulan Mo, Dexu Luo, Yi Yang, Jialin Hu, Chenqing Ye, Longxiang Lin, Chuanshan Xu, Wenjie Chen   +8 more
doaj   +1 more source

Does pattern of 5-aminolevulinic acid (5-ALA) residual intra-operatively predict worse outcome in glioblastoma? [PDF]

Brain Spine
Manik V, Fayez F, Shyam G, Kalaitzoglou D, Sathali A, Chowdhury Y, Sim V, MacDonald M, Mannava A, Soumpasis C, Ghimire P, Mirza AB, Chia K, Main S, Ashkan K, Bhangoo R, Gullan R, Brazil L, Al-Salihi O, Vergani F, Swampillai A, Lavrador JP.   +21 more
europepmc   +2 more sources

Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy

Nature Communications, 2022
5-Aminolevulinic acid-based photodynamic therapy heavily depends on the biological transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an effective delivery system and imaging navigation are major hurdles in ...
Gang He, Yashi Li, Muhammad Rizwan Younis, Lian-Hua Fu, Ting He, Shan Lei, Jing Lin, Peng Huang   +7 more
doaj   +1 more source

5-aminolevulinic Acid and Surgical Margin Analysis in Calvarial Metastasis with Pericranium or Dural Extension: Technical Note

Brazilian Neurosurgery, 2020
Metastasis to the calvarium with direct pericranium or dural infiltration may be treated with radical surgical removal in selected cases. We describe microsurgical resection of calvarial metastases with fluorescence-guided technique using 5 ...
Erasmo Barros da Silva Junior, Joseph Franklin Chenisz da Silva, Maurício Coelho Neto, Marcella Santos Cavalcanti, Ricardo Ramina   +4 more
doaj   +1 more source

Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]

, 2002
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Bergner, Albrecht, Maier, Irmgard, Gamarra, Fernando, Al-Batran, Salah, Baumgartner, Reinhold, Wagner, Simon, Castro, Mirna, Hautmann, Hubert, Huber, Rudolf M.   +8 more
core   +1 more source

Neuroprotective effects of 5-aminolevulinic acid against neurodegeneration in rat models of Parkinson's disease and stroke

Journal of Pharmacological Sciences, 2020
Oxidative stress is associated with the progression of the neurodegenerative diseases Parkinson's disease (PD) and cerebral ischemia. Recently, 5-aminolevulinic acid (5-ALA), an intermediate in the porphyrin synthesis pathway, was reported to exert ...
Masanori Hijioka, Kanori Kitamura, Daijiro Yanagisawa, Kaneyasu Nishimura, Kazuyuki Takata, Masatoshi Inden, Yoshihisa Kitamura   +6 more
doaj   +1 more source

Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]

, 1999
Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Kriegmair, Martin, Knüchel, Ruth, Stepp, Helmut, Zaak, Dirk, Stepp, Herbert, Hofstetter, Alfons, Baumgartner, Reinhold, Dirk Zaak, Helmut Stepp, Reinhold Baumgartner, Martin Kriegmair, Alfons Hofstetter, Herbert Stepp, Ruth Knuechel   +13 more
core   +1 more source

PP40. SPECIFICITY AND TOXICITY OF 5-AMINOLEVULINIC ACID (5-ALA – GLIOLAN TM) ON CORE AND INVASIVE GLIOBLASTOMA CELL POPULATIONS [PDF]

Neuro Oncol, 2017
Wood M, Estevez-Cebrero D, Smith D.
europepmc   +3 more sources

Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - In vivo experiments on the dunning rat tumor model [PDF]

, 2004
Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX ( PPIX) in an in vivo tumor ...
Schneede, Peter, Lein, Michael, Bise, Karl, Zaak, Dirk, Baumgartner, Reinhold, Stocker, Susanne, Höppner, Michael, Kriegmair, Martin, Knüchel, Ruth, Hofstetter, Alfons, Frimberger, Dominic, Sroka, Ronald, Reich, Oliver   +12 more
core   +1 more source

5-Aminolevulinic Acid (5-ALA): Analysis of Preclinical and Safety Literature

Food and Nutrition Sciences, 2013
Problem: 5-ALA has been used for many years at relatively high dose amounts in single doses for photodynamic therapy and immunofluorescence of tumors. An analysis of compiled data relating to safety and any side-effects about the use of 5-ALA at low doses has not yet been published.
Michael H. Perez, Beatriz L. Rodriguez, Terry T. Shintani, Keitaro Watanabe, Setsuko Miyanari, Rosanne C. Harrigan   +5 more
openaire   +2 more sources