Advancements and Challenges in Salivary Metabolomics for Early Detection and Monitoring of Systemic Diseases. [PDF]
Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Zhao X +8 more
europepmc +2 more sources
Photodynamic therapy in the treatment of extramammary paget’s disease
Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on the effectiveness of different methods, there is no single therapeutic approach to the treatment of patients ...
E. V. Filonenko, V. Ivanova-Radkevich
doaj +1 more source
Clinical implementation and scientific development of photodynamic therapy in Russia in 2010-2020
In recent years, the development of methods of photodynamic therapy (PDT) and photodynamic photodiagnostics (PD) in Russia is characterized by an intensive rise, steadily growing interest of specialists from various medical specialties in the method of ...
E. V. Filonenko
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Fluorescent diagnostics of non-melanoma skin cancer
Fluorescent diagnostics is a promising method for diagnosing non-melanocytic skin tumors, which makes it possible to identify clinically undetectable skin cancer foci and clarify the margin of the tumor lesion. The main drugs for fluorescent diagnostics
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
Photodynamic therapy opportunities for the treatment of erythroplasia of Queyrat
The review is dedicated to the analysis of the effectiveness of the treatment of erythroplasia of Queyrat (EQ) using photodynamic therapy (PDT). Particular attention is paid to the relationship between EQ and human papillomavirus (HPV) infection.
A. D. Kaprin +7 more
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Menthol and Its Derivatives: Exploring the Medical Application Potential. [PDF]
ABSTRACT Menthol, a natural organic compound and the primary component of mint, exhibits diverse biological activities, including analgesic, anti‐inflammatory, antibacterial, neuroprotective, and anticancer effects. The chemical modification of menthol, through processes such as esterification and amination, further enhances these activities, expanding
Zhang J, Hu Y, Wang Z.
europepmc +2 more sources
The time-dependent accumulation of protoporphyrin IX fluorescence in nodular basal cell carcinoma following application of methyl aminolevulinate with an oxygen pressure injection device [PDF]
Clinical TrialJournal ArticleAuthor's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseTopical protoporphyrin (PpIX)-induced photodynamic therapy (PDT) relies on the penetration of the prodrug into the skin ...
Allen, James +5 more
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Topical photodynamic therapy using different porphyrin precursors leads to differences in vascular photosensitization and vascular damage in normal mouse skin [PDF]
Different distributions of hexyl aminolevulinate (HAL), aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) in the superficial vasculature are not well studied but they are hypothesized to play an important role in topical photodynamic therapy ...
Bruijn, H.S. (Riette) de +6 more
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Molecular Simulations of Polymer-based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release. [PDF]
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Gao P +4 more
europepmc +2 more sources
The importance of iron chelation and iron availability during PpIX-induced photodynamic therapy [PDF]
This is the accepted version of the article. Please cite the published version which is available via the DOI link in this record.Background: Protoporphyrin IX (PpIX)-induced photodynamic therapy (PDT) is being utilised as a topical method of localised ...
Curnow, Alison, Pye, Andrew
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