Results 201 to 210 of about 321,714 (246)

CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate. [PDF]

Cancers (Basel)
Okechukwu CC, Ma X, Li W, D'Agostino R, Rees MG, Ronan MM, Roth JA, Gmeiner WH.   +7 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer. [PDF]

J Biol Chem
Tanihara T, Yoshida Y, Ogino T, Terada Y, Tsurusaki F, Hamasaki K, Otsuki K, Fukuoka K, Oyama K, Tsuruta A, Hamamura K, Mayanagi K, Koyanagi S, Murakami Y, Ono M, Kuwano M, Ohdo S, Matsunaga N.   +17 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Verbascoside restores gastrointestinal integrity and attenuates inflammation in a rat model of 5-FU-induced mucositis. [PDF]

Med Oncol
Chukwunyere U, Sayıner S, Mercan M, Çetinel Ş, Çaliş İ, Sehirli AÖ.   +5 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Targeting DKC1/NF-κB axis suppresses tumorigenesis and enhances 5-FU sensitivity in gastric cancer. [PDF]

Cancer Cell Int
Wang T, Zhang H, Feng Y, Yang Y.
europepmc   +1 more source

Warfarin–5-FU interactions

Annals of Oncology, 2006
openaire   +1 more source

Correction: Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis. [PDF]

Front Pharmacol
Siegel R, Schlosser-Hupf S, Müller-Schilling M, Kharroubi SA, Gessner A, El-Najjar N.   +5 more
europepmc   +1 more source