Verbascoside restores gastrointestinal integrity and attenuates inflammation in a rat model of 5-FU-induced mucositis. [PDF]
Chukwunyere U +5 more
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Correction: Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis. [PDF]
Siegel R +5 more
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Synthesis of 5-Fluorouracil (5-FU) coated platinum nanoparticles and apoptotic effects on U87 human glioblastoma cells. [PDF]
Abed A +6 more
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Intergroup randomized phase III study of adjuvant FOLFIRI, FOLFOX, or 5-FU/leucovorin for stage II/III rectal cancer: ECOG-ACRIN E3201. [PDF]
Kam AE +18 more
europepmc +1 more source
PRMT1-catalyzed NUSAP1 methylation enhances Notch2 signaling and 5-FU resistance in gastric cancer. [PDF]
Jiang S +6 more
europepmc +1 more source
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Formulation and characterization of Paclitaxel, 5-FU and Paclitaxel + 5-FU microspheres
International Journal of Pharmaceutics, 2004The purpose of this study was to compare the combination (Paclitaxel + 5-FU microspheres) with a single drug chemotherapy (Paclitaxel and 5-FU microspheres) against metastatic breast cancer cell line (MDA-MB 435 S). The physicochemical characteristics of the microspheres (i.e.
Anshul, Gupte, Kadriye, Ciftci
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5-fluorouracil (5-FU) is a chemotherapeutical agent used to treat cancers including breast and colorectal. Working as an antimetabolite to prevent cell proliferation, it primarily inhibits the enzyme thymidylate synthase blocking the thymidine formation required for DNA synthesis.
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Conversion of a Nŏvel 5-Fluorouracil (5-FU) Derivative to 5-FU in Rats
Journal of Urology, 1983The converting efficiency of a novel 5-FU derivative, 1, 3-didecanoyl-2-[6-[(5-fluorouracil-l-yl) carbonylamino] hexanoyl]glyceride (DFUG), to 5-FU was investigated in rat plasma. The degradation half-life of DFUG was 4.04 min when DFUG was incubated in rat plasma at 37 degrees C, though DFUG was considerably stable in buffers having different pH ...
K, Takada, H, Yoshikawa, S, Muranishi
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