Results 21 to 30 of about 11,748,335 (151)

The Effect of Brain Serotonin on the Physiological Function

Psychiatry and Clinical Psychopharmacology, 2021
Serotonin (5-HT) is one of the newer neurotransmimmetrs to be recognized for physiological importance. 5-HT is involved in a variety of central nervous system function, such as control of the cardiovascular system, emotional behaviour, cerebral blood ...
Baria ÖZTAŞ
doaj  

Urinary 5-HIAA Excretion is not Increased in Patients with Head and Neck Paragangliomas

The International Journal of Biological Markers, 2012
Background Case reports have documented carcinoid-like features in head and neck paragangliomas (HNPGLs), which, in addition to catecholamine storing granules, may also contain granules with serotonin.
Leonie T. Van Hulsteijn, Nicolette Van Duinen, Johannes A. Romijn, Johannes W.A. Smit, Eleonora P.M. Corssmit   +4 more
doaj   +1 more source

Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit

Reproductive Biology and Endocrinology, 2023
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental functions, fetal development ...
Frantisek Staud, Xin Pan, Rona Karahoda, Xiaojing Dong, Petr Kastner, Hana Horackova, Veronika Vachalova, Udo R. Markert, Cilia Abad   +8 more
doaj   +1 more source

Human platelet 5-hydroxyindoleacetic acid concentrations are meager and unlikely to be physiologically active or play a role in inflammation

Hematology
Objectives A crucial role for platelet 5-hydroxyindoleacetic acid (5-HIAA, the principal serotonin metabolite) in human immune response and inflammation has been claimed. We have attempted to assess the likelihood of such a role for platelet 5-HAA.
George M. Anderson, Martijn Van Faassen, Ido P. Kema   +2 more
doaj   +1 more source

Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels

Frontiers in Surgery, 2022
IntroductionCarcinoid heart disease (CHD) is a consequence of neuroendocrine tumors releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart valves, causing fibrosis, and eventually right heart failure.
Husnain Abbas Shah, Vandana Sagar, Simon Hughes, Amardeep Khanna, Ivan Yim, Freya Lodge, Harjot Singh, Tessa Oelofse, Críostóir Ó'Súilleabháin, Hema Venkataraman, Shishir Shetty, Richard Steeds, Stephen Rooney, Tahir Shah   +13 more
doaj   +1 more source

Brain 5-HIAA.

, 2012
Brain 5-HIAA content in ng/mg tissue in (a) prefrontal cortex (b) frontal cortex and (c) hippocampus. Animals were treated as described in Figure 2. Only vehicle treated animals are shown. N = 5–6/group.
Andrew Arrant (163092), Florian Daniel Zepf (163102), Caroline Sarah Biskup (163085), Amanda E. D. Van Swearingen (163095), Cristina L. Sánchez (163088), Cynthia Kuhn (163099)   +5 more
core   +1 more source

Increase of Urinary 5-Hydroxyindoleacetic Acid Excretion but Not Serum Chromogranin a Following Over-The-Counter 5-Hydroxytryptophan Intake

Canadian Journal of Gastroenterology, 2008
BACKGROUND: 5-hydroxyindoleacetic acid (5-HIAA) excretion is commonly measured for biochemical detection of carcinoid tumours. A 77-year-old woman was referred for elevated 24 h urine 5-HIAA excretion (510 μmol/day; normal is less than 45 μmol/day) and ...
Tisha Joy, Grace Walsh, Sonya Tokmakejian, Stan HM Van Uum   +3 more
doaj   +1 more source

Concentrations of 5-HT and 5-HIAA in brain tissue.

, 2013
Using the HPLC system, we measured the tissue levels of serotonin (5-HT) and its metabolite 5-hydroxyindolacetic acid (5-HIAA) in several brain areas. Both 5-HT and 5-HIAA concentrations were decreased in the hippocampus (A/B), the cortex (C/D) and the ...
Michelle S. Zajac (348573), Terence Y. Pang (348574), Laurence Lanfumey (142164), Thibault Renoir (348572), Xin Du (208780), Leah Leang (348575), Caroline Chevarin (348576), Anthony J. Hannan (348577)   +7 more
core   +1 more source

The effect of continuous ELF-MFs on the level of 5-HIAA in the raphe nucleus of the rat. [PDF]

J Radiat Res, 2016
The aim of this study was to investigate the effect of continuous extremely low frequency magnetic fields (ELF-MFs) with a frequency of 10 Hz and an intensity of 690-720 mu T on the level of 5-hydroxyindolacetic acid (5-HIAA) in adult male Wistar rats. A
Shahbazi-Gahrouei D, Shiri L, Alaei H, Naghdi N.   +3 more
europepmc   +2 more sources

Elevated Cerebrospinal fluid 5-hydroxyindoleacetic acid in Macaques Following Early Life Stress (ELS) and Inverse Association with Hippocampal Volume: Preliminary Implications for Serotonin-Related Function in Mood and Anxiety Disorders

Frontiers in Behavioral Neuroscience, 2014
Background: Early life stress (ELS) is cited as a risk for mood and anxiety disorders, potentially through altered serotonin neurotransmission. We examined the effects of ELS, utilizing the variable foraging demand (VFD) macaque model, on adolescent ...
Jeremy D Coplan, Sasha L Fulton, Wade eReiner, Andrea eJackowski, Venkatesh ePanthangi, Tarique D Perera, Jack M Gorman, Yung-Yu eHuang, Cheuk Y Tang, Patrick R Hof, Arie eKaffman, Andrew eDwork, Sanjay J Mathew, Joan eKaufman, John J Mann   +14 more
doaj   +1 more source