Results 31 to 40 of about 11,748,335 (151)

COMPARISON BETWEEN THE URINARY ALCOHOL MARKERS EtG, EtS, AND GTOL/5-HIAA IN A CONTROLLED DRINKING EXPERIMENT [PDF]

, 2008
5-hydroxyindole-3-acetic acid (GTOL/5-HIAA) are all suggested as biomarkers for recent alcohol ingestion with longer detection times than measurement of ethanol itself. The aim of this controlled study was to compare the sensitivities and detection times
Asbjørg S, Jørg Mørland, Per T. Normann, Nicolai Stephanson, A. S. Christophersen, P. T. Normann, Anders Helander, J. Morland, Jean Paul Bernard, G. Hoiseth, A. Helander, N. Stephanson, Gudrun Høiseth, J. P. Bernard   +13 more
core   +1 more source

P03-294 - Cholesterol And Csf 5-Hiaa In Attempted Suicide

, 2010
IntroductionLow serum cholesterol has been linked to suicide and violent behaviour. The same kind of associations has been reported regarding low levels of 5-hydroxyindolacetic acid (5-HIAA) in the cerebrospinal fluid (CSF) and suicidal behaviour.
J. Jokinen, P. Asellus, P. Nordström
core   +1 more source

Inhibition of 5-hydroxyindoleacetic acid to reduce neutrophil extracellular trap production improves lung condition in chronic obstructive pulmonary disease mice

Annals of Medicine
Background Neutrophil extracellular trap (NET) correlate with chronic obstructive pulmonary disease (COPD) severity. Platelets can promote NET generation. However, serotonin alone or serotonin-deficient platelets do not adequately promote NET production.
Qiang Zeng, Lei Xue, Wu Li, Cheng Liang, Weijia Zhou, Wei Xiong, Xiaotian Dai   +6 more
doaj   +1 more source

Assessment of Serotonin Metabolite 5-hydroxyindoleacetic Acid Levels in Urine Sample for Diagnosis and Treatment Efficacy in Children with Dysfunctional Voiding and Their Interaction with Biofeedback Therapy

Journal of Urological Surgery, 2018
Objective:Dysfunctional voiding (DV), which is explained as an incoordination between the external urethral sphincter and the bladder, is a situation developing in neurologically normal children.
Bahadır Topuz, Giray Ergin, Burak Köprü, Turgay Ebiloğlu, Hasan Cem Irkılata, Yusuf Kibar, Musa Murat Dayanç   +6 more
doaj   +1 more source

Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid

Pharmaceuticals, 2022
The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ) and may contribute to cognitive ...
Korrapati V. Sathyasaikumar, Francesca M. Notarangelo, Deanna L. Kelly, Laura M. Rowland, Stephanie M. Hare, Shuo Chen, Chen Mo, Robert W. Buchanan, Robert Schwarcz   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The mediating effects of 5-HIAA on DBP and MBP.

, 2016
*: the standard coefficients relating the independent variable to the dependent variable after adjusting for 5-HIAA and potential covariates with ...
Jingli Chen (600614), Yarui Yang (3117546), Xiumei Xing (3117540), Xiaolin Su (295559), Biling Shen (3117543), Zhiqiang Zhao (201543), Yi Sun (118759), Jun Jiang (149215), Yun He (40953), Xinxia Liu (3117534), Yao Lu (185912), Xiaoyan Ou (3117537)   +11 more
core   +1 more source

Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study. [PDF]

PLoS ONE, 2017
Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are the two most common causes of dementia. Both pathologies often coexist, and AD patients with concomitant neocortical LB pathology (referred to as the Lewy body variant of AD) generally show
Satoru Morimoto, Masaki Takao, Hiroyuki Hatsuta, Yasushi Nishina, Tadashi Komiya, Renpei Sengoku, Yuta Nakano, Akiko Uchino, Hiroyuki Sumikura, Yuko Saito, Kazutomi Kanemaru, Shigeo Murayama   +11 more
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Early Experience With Evoque Transcatheter Tricuspid Valve Replacement in Carcinoid Heart Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Tricuspid regurgitation (TR) is nearly universal in carcinoid heart disease (CHD), but surgical replacement carries significant risk, and CHD was excluded from the landmark TRISCEND II trial. We present seven patients with CHD undergoing Evoque transcatheter tricuspid valve replacement (TTVR) at two tertiary centers.
Jackson S. Burton, Ben Peterson, Brian Whisenant, Anwar Tandar   +3 more
wiley   +1 more source