Results 171 to 180 of about 167,641 (233)

Altered brain serotonin 5-HT_1A receptor expression and function in juvenile Fmr1 knockout mice. [PDF]

Neuropharmacology
Saraf TS, Chen Y, Tyagi R, Canal CE.
europepmc   +1 more source

Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT_1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid. [PDF]

Neuropsychopharmacology
Kurahashi H, Kunisawa K, Tanaka KF, Kubota H, Hasegawa M, Miyachi M, Moriya Y, Hasegawa Y, Nagai T, Saito K, Nabeshima T, Mouri A.   +11 more
europepmc   +1 more source

Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm [PDF]

J Psychiatry Neurosci, 2019
Albert PR, Le François B, Vahid-Ansari F.   +2 more
europepmc   +1 more source

5-HT1A receptor, 5-HT2A receptor and serotonin transporter binding in the human auditory cortex in depression [PDF]

J Psychiatry Neurosci, 2019
Steinberg LJ, Underwood MD, Bakalian MJ, Kassir SA, Mann JJ, Arango V.   +5 more
europepmc   +1 more source

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Reduction in 5-HT1A receptor density, 5-HT1A mRNA expression, and functional correlates for 5-HT1A receptors in genetically defined aggressive rats

Journal of Neuroscience Research, 2005
The present experiments tested the hypothesis that one of the critical mechanisms underlying genetically defined aggressiveness involves brain serotonin 5-HT1A receptors. 5-HT1A receptor density, the receptor mRNA expression in brain structures, and functional correlates for 5-HT1A receptors identified as 8-OH-DPAT-induced hypothermia and lower lip ...
N K Popova, Vladimir S Naumenko, Alexander V Kulikov   +2 more
exaly   +3 more sources

Endocytosis and signaling of 5-HT1A receptor

2023
The neurotransmitter serotonin (also known as 5-hydroxytryptamine, 5-HT) regulates many important physiological as well as pathological functions in the body like psychoemotional, sensation, blood circulation, food intake, autonomic, memory, sleep, pain, etc.
, Ragini, , Sakshi, Ashok, Saini, Indra, Mani   +3 more
openaire   +2 more sources

5-HT1A Receptors in major depression

Journal of Psychopharmacology, 1990
The 5-HT 1A receptor has been studied using quantitative tritium film auto radiography in post-mortem frontal cortex of 15 cases suffering from major depression and controls matched for age, sex, post-mortem delay and storage time.
M, Yates, I N, Ferrier
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The 5-HT1A receptor: Signaling to behavior

Biochimie, 2019
The 5-HT1A receptor is highly expressed both in 5-HT neurons as a presynaptic inhibitory autoreceptor, and in many brain regions innervated by 5-HT as a post-synaptic heteroreceptor. This review examines the signaling of 5-HT1A receptors to regulate 5-HT activity and behavior. Initial findings in heterologous cell systems, neuronal cell lines, neurons,
Paul R. Albert, Faranak Vahid-Ansari
openaire   +2 more sources

5-HT1A receptor activation

NeuroReport, 1997
Systemic administration of the 5-HT1A receptor agonist 8-OH-2-(di-n-propylamino)-tetralin (8-OH-DPAT; 0.3 mg/kg, s.c.) was used to explore the effects of activation of 5-HT1A receptors on expression of mRNA coding for 5-HT1A receptor, tryptophan hydroxylase (TPH) and galanin in the ascending raphe nuclei. 8-OH-DPAT increased the hybridization signal of
H, Razani, P B, Hedlund, A C, Hansson, K, Fuxe, S O, Ogren   +4 more
openaire   +2 more sources