Results 71 to 80 of about 79,681,589 (222)

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Spiroxatrine derivatives towards 5-HT1A receptor selectivity

, 2020
Background: In our previous work, spiroxatrine was taken as reference compound to develop selective NOP ligands. Therefore, several triazaspirodecanone derivatives were synthesized.
Battisti U. M., Brasili L., Tait, Annalisa, Battisti, Umberto M., Tait A., Sorbi C., Sorbi, Claudia, Brasili, Livio   +7 more
core   +1 more source

Lateralization of the 5-HT1A receptors in the basolateral amygdala in metabolic and anxiety responses to chronic restraint stress

Amino Acids
Behavioral and functional studies describe hemispheric asymmetry in anxiety and metabolic behaviors in responses to stress. However, no study has reported serotonergic receptor (the 5-HT1A receptor) lateralization in the basolateral amygdala (BLA) in ...
Habib Valipour, Gholam Hossein Meftahi, Gila Pirzad Jahromi, Alireza Mohammadi   +3 more
doaj   +1 more source

Comparison of High and Low Affinity Serotonin 1A Receptors by PET In Vivo in Nonhuman Primates

Journal of Pharmacological Sciences, 2012
Serotonin (5-HT) 1A receptors exist in high and low affinity states. Agonist ligands bind preferentially to the high affinity state receptors, providing a more functionally relevant measure than antagonist binding.
J.S. Dileep Kumar, Matthew S. Milak, Vattoly J. Majo, Jaya Prabhakaran, Pratap Mali, Lyudmila Savenkova, J. John Mann, Ramin V. Parsey   +7 more
doaj   +1 more source

A physiologic role for serotonergic transmission in adult rat taste buds. [PDF]

PLoS ONE, 2014
Of the multiple neurotransmitters and neuropeptides expressed in the mammalian taste bud, serotonin remains both the most studied and least understood.
Luc Jaber, Fang-li Zhao, Tamara Kolli, Scott Herness   +3 more
doaj   +1 more source

Dreaming conundrum

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti, Francesca Siclari, Ivana Rosenzweig   +2 more
wiley   +1 more source

In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice [PDF]

, 2003
In the dorsal raphe nucleus (DR), extracellular serotonin (5-HT) regulates serotonergic transmission through 5-HT1A autoreceptors. In this work we used in vivo microdialysis to examine the effects of stressful and pharmacological challenges on DR 5-HT ...
Analía Bortolozzi, Miklos Toth, Adell, Albert, Mercè Amargós-Bosch, Artigas, Francesc, Toth, Miklos, Albert Adell, Francesc Artigas, Bortolozzi, Analía, Amargós-Bosch, Mercè   +9 more
core   +1 more source

Dual role of endogenous serotonin in 2,4,6-trinitrobenzene sulfonic acid-induced colitis

Frontiers in Pharmacology, 2016
Background and Aims: Changes in gut serotonin content have been described in Inflammatory Bowel Disease and in different experimental models of colitis: the critical role of this monoamine in the pathogenesis of chronic gastrointestinal inflammation is ...
Alberto eRapalli, Simona eBertoni, Valentina eArcaro, Francesca eSaccani, Andrea eGrandi, Valentina eVivo, Anna Maria eCantoni, Elisabetta eBarocelli   +7 more
doaj   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Receptor 5-HT1A i ISRS : escurçament de la resposta antidepressiva [PDF]

, 2018
Els fàrmacs antidepressius necessiten unes quantes setmanes per aconseguir una resposta clínica (Trivedi et al., 2006). Una possible explicació és que l'augment de la concentració de serotonina (5-HT) extracel·lular produïda pels inhibidors de la ...
Oller Canet, Silvia, Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal   +1 more
core   +1 more source