Results 71 to 80 of about 167,641 (233)

Receptores 5-HT1B/1D presentes no hipotálamo posterior medial e núcleo paraventricular envolvidos no controle serotonérgico da ingestão de alimento em pombos (Columba livia) [PDF]

, 2005
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em NeurociênciasNo presente estudo, investigou-se a presença de receptores serotonérgicos no hipotálamo posterior medial (PMH) e no ...
Poffo, Marine Josiane
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Serotonergic Modulation of Absence-Like Seizures in Groggy Rats: a Novel Rat Model of Absence Epilepsy

Journal of Pharmacological Sciences, 2010
To explore the role of the serotonergic system in modulating absence seizures, we examined the effects of 5-HT1A and 5-HT2 agonists on the incidence of spike-and-wave discharges (SWD) in Groogy (GRY) rats, a novel rat model of absence-like epilepsy.
Yukihiro Ohno, Nobumasa Sofue, Takuji Imaoku, Eri Morishita, Kenta Kumafuji, Masashi Sasa, Tadao Serikawa   +6 more
doaj   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Efeitos da administração sistêmica de 5-HT e 8-OH-DPAT sobre os estados de vigília e sono de pombos (Columba livia) [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasInvestigar a participação dos mecanismos serotonérgicos sobre a regulação dos estados de sono e vigília em pombos ...
Hoeller, Alexandre Ademar
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The 5-HT1A receptor and the stimulus effects of LSD in the rat [PDF]

Psychopharmacology, 2005
It has been suggested that the 5-HT1A receptor plays a significant modulatory role in the stimulus effects of the indoleamine hallucinogen lysergic acid diethylamide (LSD).The present study sought to characterize the effects of several compounds with known affinity for the 5-HT1A receptor on the discriminative stimulus effects of LSD.Twelve male ...
C J, Reissig, J R, Eckler, R A, Rabin, J C, Winter   +3 more
openaire   +2 more sources

Efeitos ingestivos e coportamentais de microinjeção de metergolina ou 8-OH-DPAT no núcleo arqueado do hipotálamo e no hipotálamo lateral em ratos [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasO presente trabalho descreve uma série de experimentos realizados com o objetivo de identificar efeitos ingestivos e
Araújo, Bruno Blanco
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Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression

, 1993
Using in situ hybridization techniques, the expression of 5-HT1A receptor mRNA was measured within the hippocampal formation after bilateral adrenalectomy (ADX).
SJ Watson, DT Chalmers, SP Kwak, H Akil, A Mansour   +4 more
core   +1 more source

Lateralization of the 5-HT1A receptors in the basolateral amygdala in metabolic and anxiety responses to chronic restraint stress

Amino Acids
Behavioral and functional studies describe hemispheric asymmetry in anxiety and metabolic behaviors in responses to stress. However, no study has reported serotonergic receptor (the 5-HT1A receptor) lateralization in the basolateral amygdala (BLA) in ...
Habib Valipour, Gholam Hossein Meftahi, Gila Pirzad Jahromi, Alireza Mohammadi   +3 more
doaj   +1 more source

Comparison of High and Low Affinity Serotonin 1A Receptors by PET In Vivo in Nonhuman Primates

Journal of Pharmacological Sciences, 2012
Serotonin (5-HT) 1A receptors exist in high and low affinity states. Agonist ligands bind preferentially to the high affinity state receptors, providing a more functionally relevant measure than antagonist binding.
J.S. Dileep Kumar, Matthew S. Milak, Vattoly J. Majo, Jaya Prabhakaran, Pratap Mali, Lyudmila Savenkova, J. John Mann, Ramin V. Parsey   +7 more
doaj   +1 more source