Results 1 to 10 of about 284,594 (312)
Genome-Wide Identification of 5-HT Receptor Gene Family in Razor Clam Sinonovacula constricta and Their Circadian Rhythm Expression Analysis [PDF]
Animals, 2023 Serotonin (5-HT) is primarily distributed in the gastrointestinal and central nervous systems, where it plays a crucial role in regulating various physiological functions such as digestion, reproduction and establishing animal emotions.
Qiyi You +5 more
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5-HT Receptors and Temperature Homeostasis [PDF]
Biomolecules, 2021 The present review summarizes the data concerning the influence of serotonin (5-HT) receptors on body temperature in warm-blooded animals and on processes associated with its maintenance.
Irina P. Voronova
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Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors [PDF]
Frontiers in Immunology, 2019 Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory ...
Sandra Sacre +4 more
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The serotonergic system dysfunction in diabetes mellitus
Frontiers in Cellular Neuroscience, 2022 Most peripheral serotonin (5-HT) is synthesized in enterochromaffin cells, and most circulating 5-HT is stored in platelets. As a monoamine, 5-HT has several functions in various non-neuronal and neuronal systems.
Yan Cai +3 more
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Serotonergic signals enhanced hamster sperm hyperactivation
The Journal of Reproduction and Development, 2021 In the present study, we investigated the regulatory mechanisms underlying sperm hyperactivation enhanced by 5-hydroxytryptamine (5-HT) in hamsters. First, we examined the types of 5-HT receptors that regulate hyperactivation.
Chiyori SAKAMOTO +3 more
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Serotonin: A Potent Immune Cell Modulator in Autoimmune Diseases
Frontiers in Immunology, 2020 Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT in the central nervous system (CNS).
Minjie Wan +7 more
doaj +1 more source
Effects of 5‐HT₃ receptor antagonists on cisplatin‐induced kidney injury
Clinical and Translational Science, 2021 Nausea, vomiting, and renal injury are the common adverse effects associated with cisplatin. Cisplatin is excreted via the multidrug and toxin release (MATE) transporter, and the involvement of the MATE transporter in cisplatin‐induced kidney injury has ...
Mitsuhiro Goda +13 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood.
Melinda A. Engevik +18 more
doaj +1 more source
Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone [PDF]
, 2015 The psychoactive effects of mephedrone are commonly compared to those of 3,4-methylenedioxymethamphetamine, but because of a shorter duration of action users often employ repeated administration to maintain its psychoactive actions.
Ebling, Francis J.P. +5 more
core +4 more sources
Journal of Biological Chemistry, 2012 5-Hydroxytryptamine type 3 (5-HT(3)) receptors are cation-selective Cys loop receptors found in both the central and peripheral nervous systems. There are five 5-HT(3) receptor subunits (A-E), and all functional receptors require at least one A subunit. Regions from noncontiguous parts of the subunit sequence contribute to the agonist-binding site, and
openaire +2 more sources