Results 1 to 10 of about 126,000 (168)
Genome-Wide Identification of 5-HT Receptor Gene Family in Razor Clam Sinonovacula constricta and Their Circadian Rhythm Expression Analysis [PDF]
Animals, 2023 Serotonin (5-HT) is primarily distributed in the gastrointestinal and central nervous systems, where it plays a crucial role in regulating various physiological functions such as digestion, reproduction and establishing animal emotions.
Qiyi You +5 more
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5-HT Receptors and Temperature Homeostasis [PDF]
Biomolecules, 2021 The present review summarizes the data concerning the influence of serotonin (5-HT) receptors on body temperature in warm-blooded animals and on processes associated with its maintenance.
Irina P. Voronova
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The serotonergic system dysfunction in diabetes mellitus
Frontiers in Cellular Neuroscience, 2022 Most peripheral serotonin (5-HT) is synthesized in enterochromaffin cells, and most circulating 5-HT is stored in platelets. As a monoamine, 5-HT has several functions in various non-neuronal and neuronal systems.
Yan Cai +3 more
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Serotonergic signals enhanced hamster sperm hyperactivation
The Journal of Reproduction and Development, 2021 In the present study, we investigated the regulatory mechanisms underlying sperm hyperactivation enhanced by 5-hydroxytryptamine (5-HT) in hamsters. First, we examined the types of 5-HT receptors that regulate hyperactivation.
Chiyori SAKAMOTO +3 more
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Serotonin: A Potent Immune Cell Modulator in Autoimmune Diseases
Frontiers in Immunology, 2020 Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT in the central nervous system (CNS).
Minjie Wan +7 more
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Effects of 5‐HT₃ receptor antagonists on cisplatin‐induced kidney injury
Clinical and Translational Science, 2021 Nausea, vomiting, and renal injury are the common adverse effects associated with cisplatin. Cisplatin is excreted via the multidrug and toxin release (MATE) transporter, and the involvement of the MATE transporter in cisplatin‐induced kidney injury has ...
Mitsuhiro Goda +13 more
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Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood.
Melinda A. Engevik +18 more
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Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
International Journal of Molecular Sciences, 2023 Serotonin acts solely via 5-HT4-receptors to control human cardiac contractile function. The effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as well as arrhythmias, in the human heart. In addition, 5-HT4-receptors may play a role in sepsis, ischaemia, and reperfusion.
Joachim Neumann +3 more
openaire +4 more sources
Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes
Cells, 2022 Serotonin receptor 5-HT2A and tropomyosin receptor kinase B (TrkB) strongly contribute to neuroplasticity regulation and are implicated in numerous neuronal disorders.
Tatiana Ilchibaeva +7 more
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Dynamic 5-HT2C receptor editing in a mouse model of obesity.
PLoS ONE, 2012 The central serotonergic signalling system has been shown to play an important role in appetite control and the regulation of food intake. Serotonin exerts its anorectic effects mainly through the 5-HT(1B), 5-HT(2C) and 5-HT(6) receptors and these are ...
Harriët Schellekens +4 more
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