Results 41 to 50 of about 284,594 (312)

Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis

Frontiers in Pharmacology, 2013
Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT1A autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as ...
Naozumi eAraragi, Boris eMlinar, Gilda eBaccini, Lise eGutknecht, Klaus-Peter eLesch, Renato eCorradetti   +5 more
doaj   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu, Araki, Hiroaki, Gomita, Yutaka, Kawasaki, Hiromu, Kitamura, Yoshihisa, Suemaru, Katsuya, Umeda, Yuichi, Yamaguchi, Takumi   +7 more
core   +1 more source

Influences of 5-hydroxytriptamine on sperm hyperactivation and in vitro fertility in rats

The Journal of Reproduction and Development
The neurotransmitter, 5-hydroxytriptamine (5-HT), is well known. Furthermore, it enhances the acrosome reaction, hyperactivation, and in vitro fertilization (IVF) success in hamsters and mice.
Yuki KOYANO, Masakatsu FUJINOKI
doaj   +1 more source

Hippocampal 5-HT1A receptor and spatial learning and memory

Frontiers in Pharmacology, 2015
Spatial cognition is fundamental for survival in the topographically complex environments inhabited by humans and other animals. The hippocampus, which has a central role in spatial cognition, is characterized by high concentration of serotonin (5 ...
Yifat eGlikmann-Johnston, Yifat eGlikmann-Johnston, Michael Martin Saling, Michael Martin Saling, David C Reutens, Julie C Stout   +5 more
doaj   +1 more source

Serotonin regulates prostate growth through androgen receptor modulation [PDF]

, 2017
Serotonin regulates prostate growth through androgen receptor modulationAging and testosterone almost inexorably cause benign prostatic hyperplasia (BPH) in Human males. However, etiology of BPH is largely unknown.
A Morgentaler, AT Cockett, AV Pechersky, AV Sarma, BG Timms, CA Wilson, CL Dakin, CS Cooper, DJ Walther, EJ Siddiqui, G Bartsch, GR Cunha, GR Cunha, JE McNeal, JE McNeal, JE Morley, JF Murray, JH Lipschutz, K Izumi, KB Egan, L Aaron, L Santamaría, L Santamaría, M Krieg, M Matsuda, MA Haghsheno, MA Islam, N Dizeyi, P Zhang, R Deanesly, R Martín, RH Sayed, RO Roberts, SJ Berry, SJ Berry, SM Harman, TM Nicholson, X Zhang   +37 more
core   +3 more sources

Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster

Neural Plasticity, 2016
Serotonin modulates various physiological processes and behaviors. This study investigates the role of 5-HT in locomotion and feeding behaviors as well as in modulation of sensory-motor circuits.
Zana R. Majeed, Esraa Abdeljaber, Robin Soveland, Kristin Cornwell, Aubrey Bankemper, Felicitas Koch, Robin L. Cooper   +6 more
doaj   +1 more source

Serotonin augments gut pacemaker activity via 5-HT3 receptors. [PDF]

PLoS ONE, 2011
Serotonin (5-hydroxytryptamine: 5-HT) affects numerous functions in the gut, such as secretion, muscle contraction, and enteric nervous activity, and therefore to clarify details of 5-HT's actions leads to good therapeutic strategies for gut functional ...
Hong-Nian Liu, Susumu Ohya, Yuji Nishizawa, Kenta Sawamura, Satoshi Iino, Mohsin Md Syed, Kazunori Goto, Yuji Imaizumi, Shinsuke Nakayama   +8 more
doaj   +1 more source

Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose [PDF]

, 2010
Diabetes and stress stimulate hippocampal 5-HT synthesis, metabolism and release. The present study was carried out to find the effects of insulin, Aegle marmelose alone and in combination with pyridoxine on the hippocampal 5-HT, 5-HT2A receptor subtype,
Pretty Abraham, Korah P Kuruvilla, Jobin Mathew, Anitha Malat, Shilpa Joy, CS Paulose   +5 more
core   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Disturbed relationship between glucocorticoid receptor and 5-HT1AR/5-HT2AR in ADHD rats: A correlation study

Frontiers in Neuroscience, 2023
ObjectiveThis work is to investigate the alterations of the central 5-hydroxytryptamine (5-HT) system in spontaneously hypertensive rats (SHR) and the correlation with the behaviors of SHR, and to explore the effects of glucocorticoid intervention on the
Xiaoxia Lin, Liang Huang, Huifang Huang, Zhongling Ke, Yanhui Chen   +4 more
doaj   +1 more source