A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao +6 more
wiley +1 more source
Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila [PDF]
Our understanding of the molecular mechanisms underlying sleep homeostasis is limited. We have taken a systematic approach to study neural signaling by the transmitter 5-hydroxytryptamine (5-HT) in drosophila. We have generated knockout and knockin lines
Cao, Y. +8 more
core +2 more sources
Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk +3 more
wiley +1 more source
5-HT1A receptor: its role in the regulation of different kinds of behavior
Brain serotonin (5-HT) is known to be involved in the control of a wide range of physiological functions as well as of different kinds of behavior. Such polyfunctionality of 5-HT is mediated by numerous 5-HT receptors.
V. S. Naumenko +2 more
doaj +1 more source
Serotonergic Modulation of Neurovascular Transmission: A Focus on Prejunctional 5-HT Receptors/Mechanisms. [PDF]
González-Hernández A +3 more
europepmc +1 more source
A corticostriatalis pálya szerepének vizsgálata schizoprénia modellben in vitro = The role of corticostrital neurons in schizophrenia model [PDF]
Kortikostriátális agyszeletkészítményt fejlesztettünk ki, mely lehetővé teszi a Gluerg, GABAerg, DAerg neurotranszmisszió kölcsönhatásainak vizsgálatát a striátum állományában.
Hársing, László Gábor +1 more
core
Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex [PDF]
El pdf del artículo es la versión post-print.The systemic administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists has been considered as a pharmacological model of schizophrenia.
Adell, Albert +2 more
core +2 more sources
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann +2 more
wiley +1 more source
Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease. [PDF]
Neumann J, Hofmann B, Dhein S, Gergs U.
europepmc +1 more source
Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives [PDF]
Aminoindanes, piperazines, and pipradrol derivatives are novel psychoactive substances found in "Ecstasy" tablets as replacements for 3,4-methylenedioxymethamphetamine (MDMA) or substances sold as "ivory wave." The pharmacology of these MDMA- and ...
Hoener, Marius C. +4 more
core +1 more source

