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Molecular biology of 5-HT receptors

Trends in Pharmacological Sciences, 1989
Within the past six months, isolation of cDNA or genomic clones has been reported for three 5-HT receptors, the 5-HT1C, 5-HT1A and 5-HT2 subtypes. As members of the G protein receptor superfamily, all three 5-HT receptor clones encode single-subunit proteins containing approximately 450 amino acids arrayed as seven interconnected transmembrane segments.
openaire   +2 more sources

The behavioural response to 5-HT receptor agonists and subtypes of the central 5-HT receptor

Trends in Pharmacological Sciences, 1985
Abstract The analysis of the role of 5-hydroxytryptamine (5-HT)-containing neurons in the control of behaviour is complicated by the diverse functional effects that may follow the activation of the multiple types of recognition site for 5-HT that have recently been identified in the CNS, and the lack of specificity inherent in many of the 5-HT ...
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MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors?

International journal of immunopharmacology, 2000
A possible interaction of immunomodulator muramyl dipeptide (MDP) with 5-HT(7) (5-hydroxytryptamine) receptors was investigated. The activation of 5-HT(7) receptors relaxes the guinea-pig distal ileum. The whole ileum segments were, therefore, cut and placed into the bath.
J, Sevcík   +3 more
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5-HT receptors and migraine

1990
Migraine is a vascular headache but its pathophysiology is complex and multifactorial. Of the many pathophysiological factors that are implicated in migraine, changes in the metabolism of 5-hydroxytryptamine (5-HT) are the best documented. During the headache phase of migraine, urinary excretion of 5-hydroxyindoleacetic acid increases, whereas the ...
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Electrophysiology of 5-HT Receptors

2000
Within the past decade, molecular cloning techniques have confirmed that 5-hydroxytryptamine (5-HT) receptor subtypes, originally predicted from radioligand binding and functional studies (e.g., 5-HT1, 5-HT2, 5-HT3, 5-HT4), represent separate and distinct gene products. This knowledge has had a crucial impact on electrophysiological approaches to the 5-
G. K. Aghajanian, R. Andrade
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Cloning of new 5-HT receptors

International Clinical Psychopharmacology, 1993
T W, Lovenberg   +3 more
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5-HT Receptors

2020
Kerry Layne, Albert Ferro
openaire   +1 more source

Transcriptional control of energy metabolism by nuclear receptors

Nature Reviews Molecular Cell Biology, 2022
Vincent Giguere, Charlotte Scholtes
exaly  

Interactions between the 5-HT Transporter and 5-HT Receptors.

A53. VASCULAR SMOOTH MUSCLE CELLS, 2009
W Ren, BL Fanburg
openaire   +1 more source

Mutual potentiation of plant immunity by cell-surface and intracellular receptors

Nature, 2021
Pok Man Ngou   +2 more
exaly  

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