Results 241 to 250 of about 199,847 (309)

Ventrolateral orbital cortex as a functional hub in chronic pain and comorbid depression. [PDF]

Front Neurosci
Sheng HY, Song HN, Hu MX, Shi RL, Jiang LH.   +4 more
europepmc   +1 more source

Special Issue "Serotonin in Health and Diseases". [PDF]

Int J Mol Sci
Voronezhskaya EE.
europepmc   +1 more source

Roles of synaptic cell adhesion molecules in the neuromodulatory systems. [PDF]

Mol Cells
Li J, Kawasawa YI, Uchigashima M, Futai K.   +3 more
europepmc   +1 more source

Review of Structural Modification and Development of Novel Tramadol Derivatives. [PDF]

Molecules
Wang N, Zhou X, Wang J, Sun L, Liu B, Yin L.   +5 more
europepmc   +1 more source

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5-HT₃receptor antagonists

Expert Opinion on Investigational Drugs, 1999
The 5-HT(3) receptor is a ligand-gated ion channel widely distributed in the central and peripheral nervous systems. Many selective 5-HT(3) receptor antagonists have been developed; animal studies with such compounds suggested their potential therapeutic value in combating emesis and a wide range of CNS diseases including anxiety, schizophrenia, drug ...
, Higgins, , Kilpatrick
openaire   +2 more sources

Molecular biology of 5-HT receptors

Behavioural Brain Research, 2008
Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family which includes the monoamine receptors and a combination of ligand-gated ion channels (5-HT3) of the Cys loop family which constitutes heteropentamers.
Jason, Hannon, Daniel, Hoyer
openaire   +2 more sources

Quinpirole — A 5-HT receptor antagonist?

Neuroscience Letters, 1991
The rate of brain monoamine synthesis was estimated in the rat by measuring the accumulation of dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) following inhibition of cerebral aromatic amino acid decarboxylase by NSD-1015 (475 mumol/kg, i.p., 30 min before decapitation).
S, Ahlenius, V, Hillegaart, A, Wijkström   +2 more
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Molecular biology of 5-HT receptors

Neuropharmacology, 1994
The receptors through which serotonin (5-hydroxytryptamine, 5-HT) produces its effects have been the subject of intense investigation, initially using both in vivo and in vitro pharmacological methods, and later radioligand binding. These approaches allowed a preliminary classification of 5-HT receptors, but the identification on subtypes was limited ...
F G, Boess, I L, Martin
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Molecular biology of 5-HT receptors

Trends in Pharmacological Sciences, 1989
Within the past six months, isolation of cDNA or genomic clones has been reported for three 5-HT receptors, the 5-HT1C, 5-HT1A and 5-HT2 subtypes. As members of the G protein receptor superfamily, all three 5-HT receptor clones encode single-subunit proteins containing approximately 450 amino acids arrayed as seven interconnected transmembrane segments.
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