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Metabolic shifts driven by host-microbial interactions. [PDF]
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Quinpirole — A 5-HT receptor antagonist?
Neuroscience Letters, 1991The rate of brain monoamine synthesis was estimated in the rat by measuring the accumulation of dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) following inhibition of cerebral aromatic amino acid decarboxylase by NSD-1015 (475 mumol/kg, i.p., 30 min before decapitation).
S, Ahlenius +2 more
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Molecular biology of 5-HT receptors
Neuropharmacology, 1994The receptors through which serotonin (5-hydroxytryptamine, 5-HT) produces its effects have been the subject of intense investigation, initially using both in vivo and in vitro pharmacological methods, and later radioligand binding. These approaches allowed a preliminary classification of 5-HT receptors, but the identification on subtypes was limited ...
F G, Boess, I L, Martin
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Molecular Neuroanatomy of 5-HT Receptors
1991Serotoninergic terminals are found throughout the brain, suggesting an involvement of 5-HT in many brain functions. The effects of 5-HT on a given neuron are dependent on the different types of receptors expressed by this neuron, their location on the neuron and the signal transduction mechanism used. In order to provide information on the localization
PALACIOS J. M +3 more
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Neuronal 5-HT receptors in the periphery
Neuropharmacology, 19845-Hydroxytryptamine (5-HT) induces responses in neurones from all branches of the mammalian peripheral nervous system. Responses may be excitatory or inhibitory and are mediated through at least four distinct receptor sites. One receptor mediates excitation in motoneurones and preganglionic sympathetic neurones and can be designated a D (or possibly 5 ...
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Heart 5-HT Receptors. A Novel 5-HT Receptor in Human Atrium
1990Receptors for 5-hydroxytryptamine (5-HT) on myocardial cells differ among species and even among different heart regions of the same species. In molluscs 5-HT enhances heart force and cyclic AMP, and lysergic acid diethylamide (LSD) is a potent agonist. In human atria 5-HT, but not LSD, increases contractile force through unknown receptors (not blocked
Alberto J. Kaumann +5 more
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5-HT antagonists and blockade of neuronal (5-HT) receptors on ganglion cells
General Pharmacology: The Vascular System, 1984Potential changes in superior cervical ganglion cells evoked by 5-HT or the nicotinic agonist, dimethyl-phenyl piperazinium (DMPP), were recorded using the sucrose-gap method and a number of putative 5-HT antagonists tested for potency and selectivity. Selective blockade of 5-HT responses was produced by 5-HT itself and, in increasing order of potency,
H L, Nash, D I, Wallis, G, Ash
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